FI68792B - TILLSLUTNINGSKAPSYL FOER EN FLASKA MED FLYTANDE CEILING MODEL - Google Patents

Description

68792

Stopper for a bottle of liquid medicine Bottle cap for a bottle with liquid medicine

The invention relates to a stopper for a bottle of liquid medicament, which enables the medicament to be dispensed using a measuring syringe.

In particular, this stopper is used for mixed, current medications for young children, i.e. as a stopper for sales bottles of mixtures. The administration of these mixtures to children has proven to be a rather difficult task in terms of both the accuracy of the dose and the ingestion of a small child. With commonly used measuring spoons and cups, dosing is not very accurate, especially for small dosing volumes. In the oral administration phase, wounds often also occur as the child strikes or spouts, leaving the dosage even more vague.

To reduce these problems, measuring syringes have been introduced to draw a suitable amount of the mixture from the bottle with good accuracy. With such a syringe, the dose can also be delivered to the child's mouth quite effortlessly without any further loss of drug. However, this procedure still has its drawbacks.

Namely, the formulations are generally quite sparingly soluble or in which the drug forms a suspension with the carrier liquid, in which case the bottle must be shaken vigorously before administration in order to obtain the correct pharmaceutical composition in the dosing syringe. In this case, the entire inside of the bottle must inevitably sticky lääkeainepeitteen a cautious operating in smearing spray the outside of the aspirating medicament into the syringe. This causes harmful staining during the oral administration phase and 2 68792 Saxony drug is wasted, resulting in a lower total dose of the drug than intended.

Efforts have been made to find a solution to the problems with the dispensing device shown in the Finnish, revoked patent application 1630/74. This device utilizes a dosing syringe such as the one mentioned above, which is used to draw the medicine from the bottle and is equipped with a suitable measuring scale to determine the correct dose amount. To eliminate scaling and other similar problems, the dispensing device is provided with a plug-like attachment that is rotatable to replace the normal stopper of the bottle at the mouth of the bottle. In this case, the bottle can be turned upside down and the amount of medicine can be drawn into the syringe. This plug-in attachment is an integral part of the dosing syringe.

However, this dispensing device also has its own problems, although it can be considered a substantial improvement over previously used dispensing methods. First, this known dispensing apparatus requires opening the stopper of the vial, whereby the inside of the stopper is securely covered by a sticky mixture after the shaking step. This makes it difficult to handle a removed plug. In addition, the drug on the inner surface of the actual stopper, when the stopper is placed on a table or elsewhere during the dosing phase, flows with considerable certainty into the threads inside the stopper, from where it enters the mouth of the bottle when it closes. The direct consequence of this is the lack of hygiene.

Another problem is clearly related to the oral delivery phase of the drug, as the large, plug-in stopper portion of the syringe does not allow the syringe to be inserted 3 68792, even partially, into the patient's mouth. And even if the stopper part is inserted into the patient's mouth, it is a drug stain that is sure to result in the patient's mouth blisters being smeared from the drug. In order to overcome this disadvantage, the application in question therefore proposes the use of a disposable hose in a place intended to facilitate emptying of the syringe. However, the use of such a separate, flexible hose can be considered quite inconvenient, especially considering that it has to penetrate into the opening in the bottom of the dispensing plug, the inner part of which is covered with medicine, with each administration.

However, the real common problem with these medicines is their safety, especially since they are intended to be administered to young children. For this reason, the generally unpleasant taste of the drug is sought to be masked by various flavors and dyes, resulting in "lemonades" that some drugs have willingly ingested by children. In this case, it is understandable that the patient himself is willing to consume the extra doses on his own, or possibly the jealous party of the sibling series also wants to get the treat in his own mouth. Nothing in known mixing bottles prevents such extra enjoyment if the bottle falls into the hands of a slightly older child. The bottle stopper can be unscrewed with reasonable force.

In particular, a substantial improvement in the safety problem of the latter, known dispensing systems, has been achieved with the liquid medicine bottle cap according to the invention, which consists of a body substantially covering the mouth of the bottle and characterized in that the body is constructed to substantially to fasten that the body part has a dispensing opening for the dispensing syringe and that the closure plug includes a closure member for closing the dispensing opening.

With this structure, it is possible to make the stopper of the vial such that it is substantially fixed at the mouth of the vial from the time the bottle is filled until it is empty, whereby the drug is dispensed through a small opening in the stopper using a dosing syringe. The term "substantially solid" means that the stopper can be removed from the mouth of the bottle by an adult, if necessary, for example in a pharmacy, if it is necessary to add a liquid carrier to the medicament before selling the medicament. This, too, is not necessary, since the carrier can be added in the pharmacy by suitable means through the dispensing opening, so that the stopper can already be placed sufficiently tightly at the mouth of the bottle in the pharmaceutical factory.

This leaves only a small dispensing opening in the vial, from which the child has the opportunity to try to get an extra dose of medicine by removing the stopper. However, it is possible to make the orifice substantially small in diameter, so that the viscous mixture does not flow from the orifice, but a substantial suction force is required to extend it, which can only be obtained with a measuring syringe. However, the use of a measuring syringe is in practice a superior task for the child. And if a child were to seek medicine from a measuring orifice by sucking, even in the worst case, it would come from a narrow orifice, even over a long period of time, in small doses, making the company most likely to be detected.

In addition to facilitating the use of the measuring syringe, a special 68792 plug according to the invention is provided with an embodiment in which a cylindrical seat is made around the measuring opening, the inner dimension of which corresponds to the outer dimension of the measuring syringe with a suitable clearance. In this case, a small air opening can be made in the bottom area of the socket, opening outside the body of the socket, whereby the suction force is canceled by the air flowing from the opening when sucked from the mouth of the socket and does not affect the contents of the bottle.

Furthermore, the use of the plug according to the invention can be considered quite effortless and hygienic. The dosing accuracy of the drug is also good and it is as easy as possible to take the drug into the patient's mouth or mix it with the food dose.

Namely, it is possible to construct the closure member of the stopper according to the invention so as to close the entire length of the dispensing opening, so that during the shaking phase the bottle only comes into contact with the detachable parts of the bottle. . The dispensing opening itself, on the other hand, remains clean during the shaking phase due to the closing pin. Also during the suction phase of the drug, the walls of the dispensing opening do not get worse, as the dispensing opening and the tip of the syringe are dimensioned to each other so that the tip of the syringe extends substantially to the inner surface of the stopper body. when removing the syringe from the dispensing opening. The support seat of the syringe allows the shaking step only after the closing member has been removed and the tip of the syringe is in the measuring opening, which further improves hygiene.

6,68792

The invention is explained by means of the accompanying drawing, in which

Figure 1 shows an embodiment of the invention as a whole, with the closure member removed and

Figure 2 shows a top view of the body of the plug.

In the embodiment shown, the plug according to the invention consists of a body part 1, which may have a shape corresponding to a conventional screw plug. With this body part, the stopper is screwed into the correspondingly shaped mouthpiece of the vial. A small dispensing opening 2 is made in the middle of the body, which is shown in Fig. 2. The opening is covered by a plug closing member 3, which may be shaped like a conventional screw plug and preferably be provided with a pin-shaped closure 4 dimensioned to seal the dispensing opening 2. The dispensing opening 2 is preferably conically tapered inwards, the closing pin 4 being shaped accordingly. Likewise, it is advantageous to shape the tip of the measuring syringe accordingly.

In the embodiment described in the drawing, a cylindrically projecting seat sleeve 5 is made in the body 1 of the plug, the inside of which is dimensioned to surround the measuring syringe with a suitable clearance. In this case, the measuring syringe can be inserted into the stopper quite easily, whereby the seat guides the tip part of the syringe precisely into the dosing opening. Thanks to the seat, the syringe also remains firmly in the stopper when the medicine is sucked into it, which makes it possible to use an appropriate grip with the amount of medicine intended to fill the syringe. According to a preferred embodiment, the seat is provided with a notch 6 extending towards its bottom part, which makes it possible to list the drug surface in the syringe from its 0 point. Of course, there may be more of these notches within the limits dictated by the stability of the placenta. The seat casing can be provided with an air hole 7 still passing through its lower part to prevent an unintentional suction effect in the seat sleeve.

The body part 1 of the stopper itself can, of course, be shaped like a threaded stopper, as shown in the exemplary embodiment, but it can also be pressed against the mouth of the bottle. "Snap" infection. To ensure the safety of the body against unintentional opening, it can be dimensioned relative to the bottle so that the thread can be threaded to the mouth of the bottle so tight that it does not open except by explicit, reasonable force. In addition to or in addition to this, the lower edge of the body part may be provided with a separate, inwardly pivotable locking skirt with which the body part can be locked at the mouth of the bottle, either fixedly or with reasonably difficult to remove.

Claims (7)

8 68792 * A stopper for a bottle of liquid medicament comprising a body part (1) substantially covering the mouth of the bottle, characterized in that the body part (1) is designed to be attached to the mouth of the bottle substantially inseparably with respect to the dispensing of the medicament, the body part having a dispensing opening (2). ) for the dosing syringe and that the stopper includes a closure member (3) for closing the dosing opening (2). Stopper according to Claim 1, characterized in that the metering opening (2) is conically tapered inwards. Closure plug according to Claim 1 or 2, characterized in that the closure element (3) is provided with a pin (4) corresponding to the shape of the dispensing opening for sealing the dispensing opening tightly. Stopper according to one of the preceding claims 1 to 3, characterized in that the body part (1) is provided with a substantially cylindrical seat (5) projecting therefrom for a dosing syringe, the bottom of which has said dosing opening (2) for the tip part of the dosing syringe. Stopper according to Claim 4, characterized in that the seat (5) is provided with a notch (6) in its jacket surface for detecting the O-point of the measuring scale of the dosing syringe. Closure plug according to Claim 4 or 5, characterized in that the jacket of the seat (5) is provided with a through-going, small-diameter air opening (7) at the end connected to the body part (1). Stopper according to one of the preceding claims 1 to 6, characterized in that the body part (1) is provided with an inwardly directed locking skirt for tightly rotating the body part onto the mouth of the vial.