FI67851B - Foerfarande foer framstaellning av nya dopaminagonistiskt verkande benso(4,5)pyrano(2,3c)pyrrolderivat - Google Patents

Foerfarande foer framstaellning av nya dopaminagonistiskt verkande benso(4,5)pyrano(2,3c)pyrrolderivat Download PDF

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Publication number
FI67851B
FI67851B FI820749A FI820749A FI67851B FI 67851 B FI67851 B FI 67851B FI 820749 A FI820749 A FI 820749A FI 820749 A FI820749 A FI 820749A FI 67851 B FI67851 B FI 67851B
Authority
FI
Finland
Prior art keywords
compound
formula
hydrogen
pyrano
alkyl
Prior art date
Application number
FI820749A
Other languages
English (en)
Finnish (fi)
Other versions
FI820749L (fi
FI67851C (fi
Inventor
Hubert Jan Jozef Loozen
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of FI820749L publication Critical patent/FI820749L/fi
Publication of FI67851B publication Critical patent/FI67851B/fi
Application granted granted Critical
Publication of FI67851C publication Critical patent/FI67851C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C62/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C62/30—Unsaturated compounds
    • C07C62/34—Unsaturated compounds containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Claims (2)

1. Förfarande för framställning av nya dopaminagonis-tiskt verkande benso/4,5_/pyrano/2!, 3c7pyrrolderivat med for-5 mein I eller farmaceutiskt godtagbara syraadditionssalter därav, 'yJTJ' ’ , “ Li i VV'' R2 i vilken formel och betyder väte, C^-C^-alkyl, C^-C^-15 alkoxi, bensyloxi, hydroxi, metylendioxi eller acyloxi, som är härledd frän en alifatisk C^-C^-karboxylsyra eller bensoe-syra, och R^ betyder väte, C^-Cg-alkyl eller fenyl-C^-C^-alkyl, varvid fenylgruppen kan vara substituerad med C^-C4~ alkoxi eller hydroxi, kännetecknat därav, att 20 en förening med formeln II eller ett syraadditionssalt därav Rt Q H I · r4 -H, J
25 R2 I
2 O väri R och R har samma betydelse som ovan och R har samma betydelse som ovan definierade R^, men kan ytterligare vara 30 en acylgrupp eller alkoxikarbonylgrupp, och Q är väte (2H) eller syre, omvandlas termolytiskt tili en förening med formeln III eller tili ett syraadditionssalt därav,
FI820749A 1980-10-18 1982-03-03 Foerfarande foer framstaellning av nya dopaminagonistiskt verkande benso(4,5)pyrano(2,3c)pyrrolderivat FI67851C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
NL8005754 1980-10-18
NL8005754A NL8005754A (nl) 1980-10-18 1980-10-18 Benzo 4,5 pyrano 2,3-c pyrrool derivaten.
EP8100164 1981-10-12
PCT/EP1981/000164 WO1982001371A1 (en) 1980-10-18 1981-10-12 Benzo(4,5)pyrano(2,3c)pyrroles,processes for their preparation and pharmaceutical preparations containing same

Publications (3)

Publication Number Publication Date
FI820749L FI820749L (fi) 1982-03-03
FI67851B true FI67851B (fi) 1985-02-28
FI67851C FI67851C (fi) 1985-06-10

Family

ID=19836032

Family Applications (1)

Application Number Title Priority Date Filing Date
FI820749A FI67851C (fi) 1980-10-18 1982-03-03 Foerfarande foer framstaellning av nya dopaminagonistiskt verkande benso(4,5)pyrano(2,3c)pyrrolderivat

Country Status (17)

Country Link
US (1) US4385056A (sv)
EP (1) EP0050387B1 (sv)
JP (1) JPS57501628A (sv)
AT (1) ATE8996T1 (sv)
AU (1) AU545254B2 (sv)
CA (1) CA1164868A (sv)
DE (1) DE3165573D1 (sv)
DK (1) DK260382A (sv)
ES (1) ES8303418A1 (sv)
FI (1) FI67851C (sv)
GR (1) GR75827B (sv)
HU (1) HU185476B (sv)
IE (1) IE51648B1 (sv)
NL (1) NL8005754A (sv)
PT (1) PT73843B (sv)
WO (1) WO1982001371A1 (sv)
ZA (1) ZA817147B (sv)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4769367A (en) * 1984-04-24 1988-09-06 Glaxo Group Limited Heterocyclic amino compounds
DE3583307D1 (en) * 1984-05-10 1991-08-01 Ciba Geigy Ag Benzo-(pyrano und thiopyrano)-pyridine.
US4721787A (en) * 1984-05-10 1988-01-26 Ciba-Geigy Corporation Process for the preparation of benzo-(pyrano and thiopyrano)-pyridines
IT1243782B (it) * 1990-08-06 1994-06-28 Maria Francesca Devoto Composizione per il controllo della moltiplicazione di animali vertebrati per mezzo di mangimi od esche contenenti degli agonisti periferici di dopamina
US5891882A (en) * 1996-12-06 1999-04-06 Abbott Laboratories Benzopyranopyrrole and benzopyranopyridine α-1 adenergic compounds
TW200924752A (en) 2007-09-17 2009-06-16 Organon Nv Tricyclic heterocyclic derivatives
US9693993B1 (en) * 2013-12-17 2017-07-04 Robert L. Knobler Method for treatment of menopausal symptoms

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3888946A (en) * 1971-03-17 1975-06-10 Little Inc A Pyrano benzopyrans
US4132709A (en) * 1976-12-20 1979-01-02 Ayerst, Mckenna & Harrison, Ltd. [2]Benzopyrano[4,3-c]pyridine derivatives and process therefor

Also Published As

Publication number Publication date
AU7648681A (en) 1982-05-11
JPS57501628A (sv) 1982-09-09
DE3165573D1 (en) 1984-09-20
HU185476B (en) 1985-02-28
ES506313A0 (es) 1983-02-01
IE51648B1 (en) 1987-01-21
EP0050387A1 (en) 1982-04-28
FI820749L (fi) 1982-03-03
NL8005754A (nl) 1982-05-17
CA1164868A (en) 1984-04-03
AU545254B2 (en) 1985-07-04
IE812439L (en) 1982-04-18
EP0050387B1 (en) 1984-08-15
ATE8996T1 (de) 1984-09-15
FI67851C (fi) 1985-06-10
WO1982001371A1 (en) 1982-04-29
PT73843B (en) 1983-01-17
PT73843A (en) 1981-11-01
DK260382A (da) 1982-06-10
ES8303418A1 (es) 1983-02-01
GR75827B (sv) 1984-08-02
ZA817147B (en) 1982-09-29
US4385056A (en) 1983-05-24

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Legal Events

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MM Patent lapsed

Owner name: AKZO N.V.