FI48840C - Process for the preparation of 5-hydroxy-5-phenyl-2,3-dihydro-5H-imidazo [2,1-a] isoindoles useful as medicaments, with a particularly appetizing effect. - Google Patents

Process for the preparation of 5-hydroxy-5-phenyl-2,3-dihydro-5H-imidazo [2,1-a] isoindoles useful as medicaments, with a particularly appetizing effect.

Info

Publication number
FI48840C
FI48840C FI680807A FI80768A FI48840C FI 48840 C FI48840 C FI 48840C FI 680807 A FI680807 A FI 680807A FI 80768 A FI80768 A FI 80768A FI 48840 C FI48840 C FI 48840C
Authority
FI
Finland
Prior art keywords
isoindoles
imidazo
medicaments
dihydro
hydroxy
Prior art date
Application number
FI680807A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI48840B (en
Inventor
William J Houlihan
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI48840B publication Critical patent/FI48840B/fi
Application granted granted Critical
Publication of FI48840C publication Critical patent/FI48840C/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00—Preparation of halogenated hydrocarbons
    • C07C17/093—Preparation of halogenated hydrocarbons by replacement by halogens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/16—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation
    • C07C51/21—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen
    • C07C51/23—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups
    • C07C51/245—Preparation of carboxylic acids or their salts, halides or anhydrides by oxidation with molecular oxygen of oxygen-containing groups to carboxyl groups of keto groups or secondary alcohol groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/34—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI680807A 1967-03-23 1968-03-22 Process for the preparation of 5-hydroxy-5-phenyl-2,3-dihydro-5H-imidazo [2,1-a] isoindoles useful as medicaments, with a particularly appetizing effect. FI48840C (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62529967A 1967-03-23 1967-03-23

Publications (2)

Publication Number Publication Date
FI48840B FI48840B (en) 1974-09-30
FI48840C true FI48840C (en) 1975-01-10

Family

ID=24505431

Family Applications (1)

Application Number Title Priority Date Filing Date
FI680807A FI48840C (en) 1967-03-23 1968-03-22 Process for the preparation of 5-hydroxy-5-phenyl-2,3-dihydro-5H-imidazo [2,1-a] isoindoles useful as medicaments, with a particularly appetizing effect.

Country Status (12)

Country Link
AT (1) AT299187B (en)
BE (1) BE712596A (en)
DE (2) DE1795758A1 (en)
DK (1) DK136117B (en)
ES (3) ES351834A1 (en)
FI (1) FI48840C (en)
FR (1) FR7623M (en)
GB (1) GB1225411A (en)
MY (1) MY7300316A (en)
NL (1) NL6803799A (en)
NO (1) NO130826C (en)
SE (1) SE335349B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1770009C2 (en) * 1968-03-20 1987-04-16 American Home Products Corp., New York, N.Y. Process for the preparation of imidazolinyl compounds
CH531511A (en) * 1969-03-05 1972-12-15 Sandoz Ag Process for the preparation of the N, o-dilithium derivative of 2-phenyl-2-imidazoline
US4200759A (en) * 1978-07-20 1980-04-29 Delmar Chemicals, Limited Preparation of imidazo[2,1-a]isoindole compounds
DE19720859A1 (en) * 1997-05-13 1998-11-19 Inst Chemo Biosensorik Electrical connection arrangement for sensor to measurement device

Also Published As

Publication number Publication date
NO130826B (en) 1974-11-11
AT299187B (en) 1972-06-12
SE335349B (en) 1971-05-24
NO130826C (en) 1975-02-19
FI48840B (en) 1974-09-30
NL6803799A (en) 1968-09-24
GB1225411A (en) 1971-03-17
MY7300316A (en) 1973-12-31
ES357216A2 (en) 1971-01-16
DK136117B (en) 1977-08-15
DK136117C (en) 1978-01-16
DE1770030A1 (en) 1971-09-23
DE1795758A1 (en) 1974-10-10
ES368450A2 (en) 1971-07-16
ES351834A1 (en) 1969-12-01
BE712596A (en) 1968-09-23
FR7623M (en) 1970-01-26

Similar Documents

Publication Publication Date Title
FI49300C (en) Process for the preparation of therapeutically active 1,4-dihydropyridine derivatives.
CA984086A (en) Process for preparing improved plastic compositions and the resulting products
FI49716C (en) Process for the preparation of 2,4-diamino-5-benzyl-pyrimidines.
FI46166C (en) Process for the preparation of technically useful 2,4,6,8,9-penta-az α-bicyclo [3.3.1] non-2,6-dienes.
FI49971C (en) Process for the preparation of microbicide-2-nitrofurfurylidenindanone derivatives.
FI46374C (en) Process for the preparation of 2'-substituted steroid- (17alpha, 16alph a-d) -oxazolines.
FI47577C (en) Process for the preparation of 2,4,7-triamino-6-phenyl-pteridines.
FI50970C (en) Process for the preparation of antifibrinolytic aminomethyl-bisyclocarboxylic acids.
FI50977C (en) Process for the preparation of 7-chloro-5-phenyl-1,4-benzodiazepines.
FI48088C (en) Process for the preparation of 5-phenyl-1H-1,4-benzodiazepine derivatives
FI49417C (en) Process for the preparation of pharmacologically active 2,3-dihydro-benz ofuran-2-carboxylic acids.
FI52096C (en) Process for the preparation of analgesically active 2,3-dihydrotiazolo (3.2.a) pyrimidin-5-ones
FI48469C (en) Process for the preparation of 1,4-benzodiazepine derivatives.
FI46724C (en) Process for the preparation of 1,18-dimethyl-5-alpha-H-androst-1-enderivat.
FI44621C (en) Process for the preparation of hypertensive 3,4-dihydroxyphenylpropane derivatives.
FI48191C (en) Process for the preparation of 2-amino-5-phenyl-3H-1,4-benzodiazepine derivatives
FI51544C (en) Process for the preparation of sweetener mixtures.
FI48470C (en) Process for the preparation of 2-amino-2H-1,4-bentsodiazepine derivatives.
FI45173C (en) Process for the preparation of 11beta-hydroxy-pregn-4-ene-3,20-dione- [1,7-alpha, 16alpha-d] -oxazolines.
FI46620C (en) Process for the preparation of derivatives of 6,6-difluoro-17alpha-ethynyl-17beta-hydroxyestr-4-en-3-ol.
FI48459C (en) Process for the preparation of pharmacologically active 5-aminopropylide n-10-methyl-5H-dibenzo [a, d / cycloheptenes.
FI45321C (en) Process for the preparation of 4,6-chloro-16-methylidene-4,6-pregnadiene- (and -1,4,6-pregnatrien -) - 3,20-diones.
FI47988C (en) Process for the preparation of 1,4-benzodiazepines
NL149798B (en) PROCESS FOR PREPARING A MEDICINAL PRODUCT WITH TUMOR-INHIBITING AND ANTI-VIRAL ACTION, FORMED MEDICINAL PRODUCT, AND PROCESS FOR PREPARING THE ACTIVE COMPOUNDS.
CA749976A (en) 4,4-bis-hydroxyphenyl-butyronitrile and process for preparing the same