FI20070041A - Improved vaccine for immunization against Flavivirus infections - Google Patents

Improved vaccine for immunization against Flavivirus infections Download PDF

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Publication number
FI20070041A
FI20070041A FI20070041A FI20070041A FI20070041A FI 20070041 A FI20070041 A FI 20070041A FI 20070041 A FI20070041 A FI 20070041A FI 20070041 A FI20070041 A FI 20070041A FI 20070041 A FI20070041 A FI 20070041A
Authority
FI
Finland
Prior art keywords
immunization against
flavivirus infections
improved vaccine
against flavivirus
flavivirus
Prior art date
Application number
FI20070041A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI118222B (en
Inventor
Franz Xaver Heinz
Steven Allison
Christian Mandl
Christian Kunz
Original Assignee
Baxter Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT0135294A external-priority patent/AT402897B/en
Priority claimed from AT0087195A external-priority patent/AT405607B/en
Application filed by Baxter Ag filed Critical Baxter Ag
Publication of FI20070041A publication Critical patent/FI20070041A/en
Application granted granted Critical
Publication of FI118222B publication Critical patent/FI118222B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5258—Virus-like particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24111—Flavivirus, e.g. yellow fever virus, dengue, JEV
    • C12N2770/24161—Methods of inactivation or attenuation
    • C12N2770/24162—Methods of inactivation or attenuation by genetic engineering
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Vaccine against flavivirus infections comprises nucleic acid encoding flavivirus proteins E and prM/M in full-length native form. Also claimed is a nucleic acid vector comprising the entire protein prM/M and E coding sequence of a flavivirus, provided that it is not an SV40-based plasmid vector.
FI20070041A 1994-07-08 2007-01-17 Improved vaccine for immunization against Flavivirus infections FI118222B (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
AT135294 1994-07-08
AT0135294A AT402897B (en) 1994-07-08 1994-07-08 Improved vaccine for immunization against tbe virus infections, and a process for its production
AT0087195A AT405607B (en) 1995-05-23 1995-05-23 Improved vaccine for immunizing against TBE virus infections, and a process for the preparation thereof
AT87195 1995-05-23

Publications (2)

Publication Number Publication Date
FI20070041A true FI20070041A (en) 2007-01-17
FI118222B FI118222B (en) 2007-08-31

Family

ID=25594155

Family Applications (2)

Application Number Title Priority Date Filing Date
FI953371A FI117974B (en) 1994-07-08 1995-07-07 An improved vaccine for immunization against TBE virus infections and a method for its preparation
FI20070041A FI118222B (en) 1994-07-08 2007-01-17 Improved vaccine for immunization against Flavivirus infections

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI953371A FI117974B (en) 1994-07-08 1995-07-07 An improved vaccine for immunization against TBE virus infections and a method for its preparation

Country Status (9)

Country Link
EP (2) EP0869184B1 (en)
AT (2) ATE206459T1 (en)
CZ (1) CZ282927B6 (en)
DE (2) DE59508988D1 (en)
DK (2) DK0869184T3 (en)
ES (2) ES2155510T3 (en)
FI (2) FI117974B (en)
HU (2) HU219503B (en)
RU (1) RU2150294C1 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE316796T1 (en) * 1997-11-20 2006-02-15 Us Army Medical Res And Materi DNA VACCINES AGAINST TICK FLAVEVATION
US7425437B2 (en) 1999-11-26 2008-09-16 Crucell Holland B.V. Vaccines against West Nile Virus
NZ535690A (en) 2002-02-26 2009-04-30 Maxygen Inc Novel flavivirus antigens
CA2591665C (en) 2004-12-20 2015-05-05 Crucell Holland B.V. Binding molecules capable of neutralizing west nile virus and uses thereof
ATE507242T1 (en) 2005-05-12 2011-05-15 Crucell Holland Bv HOST CELL-SPECIFIC BINDING MOLECULES CAPABILITY OF NEUTRALIZING VIRUSES AND APPLICATIONS THEREOF
MX2008014977A (en) 2006-06-06 2008-12-05 Crucell Holland Bv Human binding molecules having killing activity against staphylococci and uses thereof.
CA2960659C (en) 2007-11-09 2021-07-13 The Salk Institute For Biological Studies Use of tam receptor inhibitors as immunoenhancers and tam activators as immunosuppressors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE122055T1 (en) * 1987-03-20 1995-05-15 Immuno Ag DNA AND RNA MOLECULES OF THE WESTERN SUBTYPE OF TBE VIRUS, POLYPEPTIDES ENCODED BY THESE MOLECULES, AND THEIR USE.
MY109299A (en) * 1990-08-15 1996-12-31 Virogenetics Corp Recombinant pox virus encoding flaviviral structural proteins
WO1992003161A1 (en) 1990-08-27 1992-03-05 The United States Of America, Represented By The Secretary, United States Department Of Commerce Flavivirus envelope proteins with increased immunogenicity for use in immunization against virus infection
CA2102918C (en) 1992-03-11 2007-05-08 Joel R. Haynes Genetic vaccine for immunodeficiency viruses

Also Published As

Publication number Publication date
ATE198909T1 (en) 2001-02-15
ES2165109T3 (en) 2002-03-01
RU2150294C1 (en) 2000-06-10
HU219503B (en) 2001-04-28
EP0869184A2 (en) 1998-10-07
DK0691404T3 (en) 2001-03-19
EP0869184B1 (en) 2001-10-04
DE59509667D1 (en) 2001-11-08
EP0691404B1 (en) 2001-01-24
FI953371A0 (en) 1995-07-07
HU224199B1 (en) 2005-06-28
HU9903233D0 (en) 1999-11-29
FI118222B (en) 2007-08-31
CZ282927B6 (en) 1997-11-12
HUT72395A (en) 1996-04-29
EP0691404A2 (en) 1996-01-10
EP0869184A3 (en) 1999-05-12
DK0869184T3 (en) 2001-12-17
ES2155510T3 (en) 2001-05-16
CZ176995A3 (en) 1996-01-17
DE59508988D1 (en) 2001-03-01
ATE206459T1 (en) 2001-10-15
HU9501832D0 (en) 1995-08-28
FI953371A (en) 1996-01-09
EP0691404A3 (en) 1997-11-12
FI117974B (en) 2007-05-15

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