FI102457B1 - Menetelmä probukolia sisältävän, parantuneen biosaatavuuden omaavan farmaseuttisen koostumuksen valmistamiseksi - Google Patents

Menetelmä probukolia sisältävän, parantuneen biosaatavuuden omaavan farmaseuttisen koostumuksen valmistamiseksi

Info

Publication number
FI102457B1
FI102457B1 FI932769A FI932769A FI102457B1 FI 102457 B1 FI102457 B1 FI 102457B1 FI 932769 A FI932769 A FI 932769A FI 932769 A FI932769 A FI 932769A FI 102457 B1 FI102457 B1 FI 102457B1
Authority
FI
Finland
Prior art keywords
pharmaceutical composition
probucol
preparing
composition containing
improved bioavailability
Prior art date
Application number
FI932769A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI932769A0 (fi
FI932769A (fi
FI102457B (fi
Inventor
Kenneth G Bassler
Deepak S Phadke
Melissa P Neddermeyer
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of FI932769A0 publication Critical patent/FI932769A0/fi
Publication of FI932769A publication Critical patent/FI932769A/fi
Application granted granted Critical
Publication of FI102457B publication Critical patent/FI102457B/fi
Publication of FI102457B1 publication Critical patent/FI102457B1/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
FI932769A 1990-12-18 1993-06-16 Menetelmä probukolia sisältävän, parantuneen biosaatavuuden omaavan farmaseuttisen koostumuksen valmistamiseksi FI102457B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US62954090A 1990-12-18 1990-12-18
US62954090 1990-12-18
US9108565 1991-11-15
PCT/US1991/008565 WO1992010996A1 (en) 1990-12-18 1991-11-15 Enhanced bioavailability pharmaceutical composition containing probucol

Publications (4)

Publication Number Publication Date
FI932769A0 FI932769A0 (fi) 1993-06-16
FI932769A FI932769A (fi) 1993-06-16
FI102457B FI102457B (fi) 1998-12-15
FI102457B1 true FI102457B1 (fi) 1998-12-15

Family

ID=24523438

Family Applications (1)

Application Number Title Priority Date Filing Date
FI932769A FI102457B1 (fi) 1990-12-18 1993-06-16 Menetelmä probukolia sisältävän, parantuneen biosaatavuuden omaavan farmaseuttisen koostumuksen valmistamiseksi

Country Status (17)

Country Link
EP (1) EP0563112B1 (no)
JP (1) JP3127998B2 (no)
KR (1) KR0177845B1 (no)
AT (1) ATE117200T1 (no)
AU (1) AU647563B2 (no)
CA (1) CA2097827C (no)
DE (1) DE69106892T2 (no)
DK (1) DK0563112T3 (no)
ES (1) ES2069987T3 (no)
FI (1) FI102457B1 (no)
GR (1) GR3015837T3 (no)
HU (1) HU210565B (no)
IE (1) IE65578B1 (no)
IL (1) IL100390A (no)
NO (1) NO303526B1 (no)
NZ (1) NZ240961A (no)
WO (1) WO1992010996A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995031979A1 (en) * 1994-05-19 1995-11-30 R.P. Scherer International Corporation Solutions of aryl or heteroaryl substituted alkanoic acids in lipophilic solvents and soft gelatin capsules containing such solutions
US5858401A (en) * 1996-01-22 1999-01-12 Sidmak Laboratories, Inc. Pharmaceutical composition for cyclosporines
US6814977B1 (en) 1998-12-18 2004-11-09 Abbott Laboratories Formulations comprising lipid-regulating agents
US7014864B1 (en) 1998-12-18 2006-03-21 Abbott Laboratories Formulations comprising lipid-regulating agents
CA2355820A1 (en) * 1998-12-18 2000-06-29 Abbott Laboratories Novel formulations comprising lipid-regulating agents
US6838091B2 (en) 1998-12-18 2005-01-04 Abbott Laboratories Formulations comprising lipid-regulating agents
EP1172104A4 (en) * 1999-02-23 2002-11-27 Chugai Pharmaceutical Co Ltd PREPARATIONS FROM SOFT POCKET CAPSULES CONTAINING DIHYDROBENZOFURANE DERIVATIVES
US6719999B2 (en) 1999-03-31 2004-04-13 Abbott Laboratories Formulations comprising lipid-regulating agents
US6372251B2 (en) 1999-06-11 2002-04-16 Abbott Laboratories Formulations comprising lipid-regulating agents
WO2005037251A1 (en) * 2003-10-17 2005-04-28 Amylin Pharmaceuticals, Inc. Self-emulsifying drug delivery systems for hydrophobic therapeutic compounds
WO2024006748A1 (en) * 2022-07-01 2024-01-04 Acrotech Biopharma Inc. Pharmaceutical compositions comprising isotretinoin and processes for preparation and uses thereof
CN116617179B (zh) * 2023-05-19 2024-03-29 齐鲁制药有限公司 一种普罗布考软胶囊及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3862332A (en) * 1967-05-11 1975-01-21 Dow Chemical Co Method of lowering serum cholesterol
US4902513A (en) * 1987-07-31 1990-02-20 Jean Carvais Oral sustained release medicament

Also Published As

Publication number Publication date
EP0563112A1 (en) 1993-10-06
AU647563B2 (en) 1994-03-24
ES2069987T3 (es) 1995-05-16
AU9067891A (en) 1992-07-22
NZ240961A (en) 1994-03-25
JP3127998B2 (ja) 2001-01-29
HU210565B (en) 1995-05-29
DE69106892T2 (de) 1995-05-18
DE69106892D1 (de) 1995-03-02
FI932769A0 (fi) 1993-06-16
FI932769A (fi) 1993-06-16
KR930702965A (ko) 1993-11-29
FI102457B (fi) 1998-12-15
ATE117200T1 (de) 1995-02-15
CA2097827C (en) 2002-07-23
IL100390A (en) 1996-12-05
GR3015837T3 (en) 1995-07-31
EP0563112B1 (en) 1995-01-18
DK0563112T3 (da) 1995-04-10
NO932236D0 (no) 1993-06-17
IE914401A1 (en) 1992-07-01
IL100390A0 (en) 1992-09-06
WO1992010996A1 (en) 1992-07-09
NO303526B1 (no) 1998-07-27
KR0177845B1 (ko) 1999-03-20
CA2097827A1 (en) 1992-06-19
NO932236L (no) 1993-06-17
HU9301769D0 (en) 1993-09-28
IE65578B1 (en) 1995-11-01
JPH06503340A (ja) 1994-04-14
HUT64218A (en) 1993-12-28

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Legal Events

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PC Transfer of assignment of patent

Owner name: AVENTIS INC.

Free format text: AVENTIS INC.

PC Transfer of assignment of patent

Owner name: AVENTISUB II INC.

Free format text: AVENTISUB II INC.

MA Patent expired