ES8802330A1 - DNA synthesis - Google Patents
DNA synthesisInfo
- Publication number
- ES8802330A1 ES8802330A1 ES550390A ES550390A ES8802330A1 ES 8802330 A1 ES8802330 A1 ES 8802330A1 ES 550390 A ES550390 A ES 550390A ES 550390 A ES550390 A ES 550390A ES 8802330 A1 ES8802330 A1 ES 8802330A1
- Authority
- ES
- Spain
- Prior art keywords
- dna synthesis
- blocks
- carrier
- solid phase
- long chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
Abstract
A method of synthesizing long chain DNA, in which blocks having 4 to 8 base sequences are purely chemically ligated by a so-called solid phase method (triester method) using aminated CPG as a carrier.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59281645A JPS61152695A (en) | 1984-12-26 | 1984-12-26 | Synthesis of long-chain dna |
Publications (2)
Publication Number | Publication Date |
---|---|
ES550390A0 ES550390A0 (en) | 1988-05-01 |
ES8802330A1 true ES8802330A1 (en) | 1988-05-01 |
Family
ID=17641986
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES550390A Expired ES8802330A1 (en) | 1984-12-26 | 1985-12-24 | DNA synthesis |
Country Status (9)
Country | Link |
---|---|
JP (1) | JPS61152695A (en) |
KR (1) | KR940000543B1 (en) |
CA (1) | CA1295558C (en) |
CH (1) | CH672791A5 (en) |
DE (1) | DE3544459C2 (en) |
ES (1) | ES8802330A1 (en) |
FR (1) | FR2575162B1 (en) |
GB (1) | GB2169605B (en) |
IT (1) | IT1208725B (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1989011211A2 (en) * | 1988-05-24 | 1989-11-30 | Gesellschaft Für Biotechnologische Forschung Mbh ( | Oligonucleotide bank and process for dna sequencing |
CA2133554C (en) * | 1992-04-15 | 2009-07-14 | David R. Shortle | Synthesis of diverse and useful collections of oligonucleotides |
US5516664A (en) * | 1992-12-23 | 1996-05-14 | Hyman; Edward D. | Enzymatic synthesis of repeat regions of oligonucleotides |
US6479262B1 (en) * | 2000-05-16 | 2002-11-12 | Hercules, Incorporated | Solid phase enzymatic assembly of polynucleotides |
US7205399B1 (en) | 2001-07-06 | 2007-04-17 | Sirna Therapeutics, Inc. | Methods and reagents for oligonucleotide synthesis |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR7807288A (en) * | 1977-11-08 | 1979-06-12 | Genentech Inc | POLYNUCLEOTIDE SYNTHESIS PROCESS |
DE3163811D1 (en) * | 1980-02-29 | 1984-07-05 | University Patents Inc | Process for removing trityl blocking groups from 5'-o trityl nucleosides and oligonucleotides |
EP0102995A1 (en) * | 1982-03-08 | 1984-03-21 | Celltech Limited | Polynucleotide synthesis |
EP0090789A1 (en) * | 1982-03-26 | 1983-10-05 | Monsanto Company | Chemical DNA synthesis |
IL69196A0 (en) * | 1982-08-20 | 1983-11-30 | Genex Corp | Solid phase synthesis of oligonucleotides |
DE3301833A1 (en) * | 1983-01-20 | 1984-07-26 | Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig | METHOD FOR SIMULTANEOUS SYNTHESIS OF SEVERAL OLIGONOCLEOTIDES IN A SOLID PHASE |
JP2548112B2 (en) * | 1983-09-02 | 1996-10-30 | シンジェン,インコーポレイテッド | Carrier and oligonucleotide synthesis |
CA1297437C (en) * | 1983-11-21 | 1992-03-17 | Hans Rink | Process for the preparation of protease inhibitors |
-
1984
- 1984-12-26 JP JP59281645A patent/JPS61152695A/en active Granted
-
1985
- 1985-12-16 GB GB8530915A patent/GB2169605B/en not_active Expired
- 1985-12-16 DE DE3544459A patent/DE3544459C2/en not_active Expired - Fee Related
- 1985-12-18 IT IT8548954A patent/IT1208725B/en active
- 1985-12-20 CH CH5457/85A patent/CH672791A5/fr not_active IP Right Cessation
- 1985-12-20 FR FR858518965A patent/FR2575162B1/en not_active Expired
- 1985-12-23 CA CA000498535A patent/CA1295558C/en not_active Expired - Lifetime
- 1985-12-24 ES ES550390A patent/ES8802330A1/en not_active Expired
- 1985-12-26 KR KR1019850009935A patent/KR940000543B1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
KR860005025A (en) | 1986-07-16 |
FR2575162A1 (en) | 1986-06-27 |
JPH0586400B2 (en) | 1993-12-10 |
IT8548954A0 (en) | 1985-12-18 |
ES550390A0 (en) | 1988-05-01 |
DE3544459A1 (en) | 1986-07-03 |
CA1295558C (en) | 1992-02-11 |
IT1208725B (en) | 1989-07-10 |
GB2169605A (en) | 1986-07-16 |
CH672791A5 (en) | 1989-12-29 |
GB8530915D0 (en) | 1986-01-29 |
KR940000543B1 (en) | 1994-01-24 |
JPS61152695A (en) | 1986-07-11 |
GB2169605B (en) | 1989-06-07 |
DE3544459C2 (en) | 1993-12-16 |
FR2575162B1 (en) | 1989-05-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970401 |