ES8800887A1 - 5-Lipoxygenase inhibitors for treating asthma and inflammation - Google Patents

5-Lipoxygenase inhibitors for treating asthma and inflammation

Info

Publication number
ES8800887A1
ES8800887A1 ES557095A ES557095A ES8800887A1 ES 8800887 A1 ES8800887 A1 ES 8800887A1 ES 557095 A ES557095 A ES 557095A ES 557095 A ES557095 A ES 557095A ES 8800887 A1 ES8800887 A1 ES 8800887A1
Authority
ES
Spain
Prior art keywords
substd
lower alkoxy
inflammation
treating asthma
lipoxygenase inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557095A
Other languages
Spanish (es)
Other versions
ES557095A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP13349684A external-priority patent/JPS6112642A/en
Priority claimed from JP18325384A external-priority patent/JPS6160609A/en
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Publication of ES8800887A1 publication Critical patent/ES8800887A1/en
Publication of ES557095A0 publication Critical patent/ES557095A0/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Lipoxygenase inhibitor (LPI) comprises, as active ingredient, a styrene deriv. (A) having a radical of formula (I) and contg. at least 8C (pref. at least 12C). In (I), X=OH or lower alkoxy (pref. of 1-4C) q=2 or 3. Pref. styrene deriv. (A) is of formula (A1) where Z=COOR1, COZ1Ar, CONHCmH2m+1, CO(CH2)lR4 or CpH2pR5 R1=3-10C alkyl opt. substd. by halo(s) Z1=O(CH2)nCH=CH-, NH-(CH2)nCH=CH, or NH(CH2)n n=1-4 Ar=phenyl substd. by R2 and R3 R2 and R3=H, lower alkoxy or OH m=6-14, R4=phenyl opt. substd. by OH, lower alkoxy or halo, l=0-7, provided that it is not 0 when R4=Ph R5=H or phenyl substd. by R6 and R7 R6 and R7=H, OH, lower alkoxy or halo, p=1-8 when R5=H, p=0-5, when R5=C6H3R6R7.
ES557095A 1984-06-27 1986-09-30 5-Lipoxygenase inhibitors for treating asthma and inflammation Expired ES8800887A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13349684A JPS6112642A (en) 1984-06-27 1984-06-27 Aromatic unsaturated ketone derivative
JP18325384A JPS6160609A (en) 1984-08-31 1984-08-31 Lipoxygenase inhibitor

Publications (2)

Publication Number Publication Date
ES8800887A1 true ES8800887A1 (en) 1987-12-16
ES557095A0 ES557095A0 (en) 1987-12-16

Family

ID=26467838

Family Applications (1)

Application Number Title Priority Date Filing Date
ES557095A Expired ES8800887A1 (en) 1984-06-27 1986-09-30 5-Lipoxygenase inhibitors for treating asthma and inflammation

Country Status (1)

Country Link
ES (1) ES8800887A1 (en)

Also Published As

Publication number Publication date
ES557095A0 (en) 1987-12-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603