ES8800885A1 - 5-Lipoxygenase inhibitors for treating asthma and inflammation - Google Patents
5-Lipoxygenase inhibitors for treating asthma and inflammationInfo
- Publication number
- ES8800885A1 ES8800885A1 ES557096A ES557096A ES8800885A1 ES 8800885 A1 ES8800885 A1 ES 8800885A1 ES 557096 A ES557096 A ES 557096A ES 557096 A ES557096 A ES 557096A ES 8800885 A1 ES8800885 A1 ES 8800885A1
- Authority
- ES
- Spain
- Prior art keywords
- substd
- lower alkoxy
- inflammation
- treating asthma
- lipoxygenase inhibitors
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Lipoxygenase inhibitor (LPI) comprises, as active ingredient, a styrene deriv. (A) having a radical of formula (I) and contg. at least 8C (pref. at least 12C). In (I), X=OH or lower alkoxy (pref. of 1-4C) q=2 or 3. Pref. styrene deriv. (A) is of formula (A1) where Z=COOR1, COZ1Ar, CONHCmH2m+1, CO(CH2)lR4 or CpH2pR5 R1=3-10C alkyl opt. substd. by halo(s) Z1=O(CH2)nCH=CH-, NH-(CH2)nCH=CH, or NH(CH2)n n=1-4 Ar=phenyl substd. by R2 and R3 R2 and R3=H, lower alkoxy or OH m=6-14, R4=phenyl opt. substd. by OH, lower alkoxy or halo, l=0-7, provided that it is not 0 when R4=Ph R5=H or phenyl substd. by R6 and R7 R6 and R7=H, OH, lower alkoxy or halo, p=1-8 when R5=H, p=0-5, when R5=C6H3R6R7.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16698184A JPS6144836A (en) | 1984-08-08 | 1984-08-08 | Substituted styrene derivative |
JP18325384A JPS6160609A (en) | 1984-08-31 | 1984-08-31 | Lipoxygenase inhibitor |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8800885A1 true ES8800885A1 (en) | 1987-12-16 |
ES557096A0 ES557096A0 (en) | 1987-12-16 |
Family
ID=26491165
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES557096A Expired ES8800885A1 (en) | 1984-08-08 | 1986-09-30 | 5-Lipoxygenase inhibitors for treating asthma and inflammation |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8800885A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2083891A1 (en) * | 1991-04-24 | 1996-04-16 | Univ Valencia Estudi General | Process for obtaining 2-(1-propenyl) phenol derivatives |
-
1986
- 1986-09-30 ES ES557096A patent/ES8800885A1/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2083891A1 (en) * | 1991-04-24 | 1996-04-16 | Univ Valencia Estudi General | Process for obtaining 2-(1-propenyl) phenol derivatives |
Also Published As
Publication number | Publication date |
---|---|
ES557096A0 (en) | 1987-12-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19960603 |