ES8800885A1 - 5-Lipoxygenase inhibitors for treating asthma and inflammation - Google Patents

5-Lipoxygenase inhibitors for treating asthma and inflammation

Info

Publication number
ES8800885A1
ES8800885A1 ES557096A ES557096A ES8800885A1 ES 8800885 A1 ES8800885 A1 ES 8800885A1 ES 557096 A ES557096 A ES 557096A ES 557096 A ES557096 A ES 557096A ES 8800885 A1 ES8800885 A1 ES 8800885A1
Authority
ES
Spain
Prior art keywords
substd
lower alkoxy
inflammation
treating asthma
lipoxygenase inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES557096A
Other languages
Spanish (es)
Other versions
ES557096A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Tanabe Pharma Corp
Original Assignee
Green Cross Corp Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP16698184A external-priority patent/JPS6144836A/en
Priority claimed from JP18325384A external-priority patent/JPS6160609A/en
Application filed by Green Cross Corp Japan filed Critical Green Cross Corp Japan
Publication of ES8800885A1 publication Critical patent/ES8800885A1/en
Publication of ES557096A0 publication Critical patent/ES557096A0/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Lipoxygenase inhibitor (LPI) comprises, as active ingredient, a styrene deriv. (A) having a radical of formula (I) and contg. at least 8C (pref. at least 12C). In (I), X=OH or lower alkoxy (pref. of 1-4C) q=2 or 3. Pref. styrene deriv. (A) is of formula (A1) where Z=COOR1, COZ1Ar, CONHCmH2m+1, CO(CH2)lR4 or CpH2pR5 R1=3-10C alkyl opt. substd. by halo(s) Z1=O(CH2)nCH=CH-, NH-(CH2)nCH=CH, or NH(CH2)n n=1-4 Ar=phenyl substd. by R2 and R3 R2 and R3=H, lower alkoxy or OH m=6-14, R4=phenyl opt. substd. by OH, lower alkoxy or halo, l=0-7, provided that it is not 0 when R4=Ph R5=H or phenyl substd. by R6 and R7 R6 and R7=H, OH, lower alkoxy or halo, p=1-8 when R5=H, p=0-5, when R5=C6H3R6R7.
ES557096A 1984-08-08 1986-09-30 5-Lipoxygenase inhibitors for treating asthma and inflammation Expired ES8800885A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16698184A JPS6144836A (en) 1984-08-08 1984-08-08 Substituted styrene derivative
JP18325384A JPS6160609A (en) 1984-08-31 1984-08-31 Lipoxygenase inhibitor

Publications (2)

Publication Number Publication Date
ES8800885A1 true ES8800885A1 (en) 1987-12-16
ES557096A0 ES557096A0 (en) 1987-12-16

Family

ID=26491165

Family Applications (1)

Application Number Title Priority Date Filing Date
ES557096A Expired ES8800885A1 (en) 1984-08-08 1986-09-30 5-Lipoxygenase inhibitors for treating asthma and inflammation

Country Status (1)

Country Link
ES (1) ES8800885A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2083891A1 (en) * 1991-04-24 1996-04-16 Univ Valencia Estudi General Process for obtaining 2-(1-propenyl) phenol derivatives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2083891A1 (en) * 1991-04-24 1996-04-16 Univ Valencia Estudi General Process for obtaining 2-(1-propenyl) phenol derivatives

Also Published As

Publication number Publication date
ES557096A0 (en) 1987-12-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603