ES8800216A1 - New 3-oxadiazolyl-6-oxo-5,6-di:hydro-imidazo-benzodiazepine derivs. - Google Patents

New 3-oxadiazolyl-6-oxo-5,6-di:hydro-imidazo-benzodiazepine derivs.

Info

Publication number
ES8800216A1
ES8800216A1 ES552803A ES552803A ES8800216A1 ES 8800216 A1 ES8800216 A1 ES 8800216A1 ES 552803 A ES552803 A ES 552803A ES 552803 A ES552803 A ES 552803A ES 8800216 A1 ES8800216 A1 ES 8800216A1
Authority
ES
Spain
Prior art keywords
cpd
reacting
formula
alkyl
imidazo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES552803A
Other languages
Spanish (es)
Other versions
ES552803A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrosan ApS
Original Assignee
Ferrosan ApS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK108085A external-priority patent/DK108085A/en
Priority claimed from DK108185A external-priority patent/DK108185A/en
Priority claimed from DK220385A external-priority patent/DK220385D0/en
Priority claimed from DK220485A external-priority patent/DK220485D0/en
Application filed by Ferrosan ApS filed Critical Ferrosan ApS
Publication of ES552803A0 publication Critical patent/ES552803A0/en
Publication of ES8800216A1 publication Critical patent/ES8800216A1/en
Expired legal-status Critical Current

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Abstract

The derivs. of general formula (I), in which R3 is (II) or (III) or where R2 is H, 1-6C alkyl or alkoxy-methyl or 3-6C cyclo-alkyl, R4 is H and R5 is 1-6C alkyl, or R4 and R5 together form a 2-4C alkenyl chain, Ra is 1-6C alkyl or alkoxy, or trifluoro 1-3C alkyl, are made by (a) reacting a cpd. of formula (I), in which R3 is -COOH with a cpd. of general formula (V) to give a cpd. of formula (I) in which R3 is (II) or (b) reacting a cpd. of formula (I) in which R3 is -CONHc with a cpd. R2C(OCH3)2, and reacting the prod. with NH2OH or other aminating agent to give the same prod. as in (a) or (c) reacting a cpd. of formula (I) in which R3 is -CN with NH2OH, and reacting the prod. with a cpd. (R2CO)2O, to give (I( in which R3 is (III) or (d) reacting a cpd. of formula (XI) with a cpd. R3CH2CN to give (I).
ES552803A 1985-03-08 1986-03-07 New 3-oxadiazolyl-6-oxo-5,6-di:hydro-imidazo-benzodiazepine derivs. Expired ES8800216A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK108085A DK108085A (en) 1985-03-08 1985-03-08 NEW OXADIAZOLYLIMIDAZOBENZODIAZEPINE DERIVATIVES AND PROCEDURES FOR PREPARING IT
DK108185A DK108185A (en) 1985-03-08 1985-03-08 NEW OXADIAZOLYLIMIDAZOBENZODIAZEPINE DERIVATIVES AND PROCEDURES FOR PREPARING IT
DK220385A DK220385D0 (en) 1985-05-17 1985-05-17 PROCEDURE FOR THE PREPARATION OF OXADIAZOLYL DERIVATIVES OF IMIDAZOBENZODIAZEPINES AND INTERMEDIATES FOR USING THE PROCEDURE
DK220485A DK220485D0 (en) 1985-05-17 1985-05-17 NEW OXADIAZOLYLIMIDAZOBENZODIAZEPINE DERIVATIVES AND PROCEDURES PREPARED THEREOF

Publications (2)

Publication Number Publication Date
ES552803A0 ES552803A0 (en) 1987-10-16
ES8800216A1 true ES8800216A1 (en) 1987-10-16

Family

ID=27439429

Family Applications (1)

Application Number Title Priority Date Filing Date
ES552803A Expired ES8800216A1 (en) 1985-03-08 1986-03-07 New 3-oxadiazolyl-6-oxo-5,6-di:hydro-imidazo-benzodiazepine derivs.

Country Status (1)

Country Link
ES (1) ES8800216A1 (en)

Also Published As

Publication number Publication date
ES552803A0 (en) 1987-10-16

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