ES8705896A1 - Un procedimiento para la preparacion de peptidos h-l4s-his-gly-nh y sus sales de adicion de acido farmaceuticamente aceptables. - Google Patents

Un procedimiento para la preparacion de peptidos h-l4s-his-gly-nh y sus sales de adicion de acido farmaceuticamente aceptables.

Info

Publication number
ES8705896A1
ES8705896A1 ES551399A ES551399A ES8705896A1 ES 8705896 A1 ES8705896 A1 ES 8705896A1 ES 551399 A ES551399 A ES 551399A ES 551399 A ES551399 A ES 551399A ES 8705896 A1 ES8705896 A1 ES 8705896A1
Authority
ES
Spain
Prior art keywords
bursopoietin
cells
mature
differentiation
possesses
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551399A
Other languages
English (en)
Other versions
ES551399A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Publication of ES551399A0 publication Critical patent/ES551399A0/es
Publication of ES8705896A1 publication Critical patent/ES8705896A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

METODO DE PREPARAR EL PEPTIDO H-LYS-HIS-GLY-NH2. CONSISTE EN: A) HACER REACCIONAR GLICINA PROTEGIDA EN SU GRUPO AMINO CON UNA RESINA, EN UN DISOLVENTE APROPIADO, QUEDANDO ASI ACOPLADA LA RESINA A LA GLICINA; B) FILTRAR EL PRODUCTO OBTENIDO EN LA ETAPA A), LAVARLO, SECARLO Y DESPROTEGER EL GRUPO AMINO DE LA GLICINA; C) HACER REACCIONAR EL GRUPO DE LA ETAPA B) CON L-HISTIDINA PROTEGIDA EN SU GRUPO AMINO; D) ELIMINAR EL GRUPO PROTECTOR DEL PRODUCTO DE LA ETAPA C); E) HACER REACCIONAR EL CONJUGADO PROCEDENTE DE LA ETAPA D) CON L-LISINA PROTEGIDA EN SUS DOS GRUPOS AMINO; Y F) INCIDIR EL PEPTIDO PROTEGIDO DE LA RESINA Y ELIMINAR LOS GRUPOS PROTECTORES PARA OBTENER EL PEPTIDO DESEADO. TIENE UTILIDAD EN LA PRODUCCION DE ANTICUERPOS.
ES551399A 1985-01-31 1986-01-29 Un procedimiento para la preparacion de peptidos h-l4s-his-gly-nh y sus sales de adicion de acido farmaceuticamente aceptables. Expired ES8705896A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/681,971 US4584284A (en) 1985-01-31 1985-01-31 Bursopoietin

Publications (2)

Publication Number Publication Date
ES551399A0 ES551399A0 (es) 1987-05-16
ES8705896A1 true ES8705896A1 (es) 1987-05-16

Family

ID=24737644

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551399A Expired ES8705896A1 (es) 1985-01-31 1986-01-29 Un procedimiento para la preparacion de peptidos h-l4s-his-gly-nh y sus sales de adicion de acido farmaceuticamente aceptables.

Country Status (13)

Country Link
US (2) US4584284A (es)
EP (1) EP0190048B1 (es)
JP (1) JPS61218598A (es)
AT (1) ATE71953T1 (es)
AU (1) AU593231B2 (es)
CA (1) CA1276398C (es)
DE (1) DE3683507D1 (es)
DK (1) DK47686A (es)
ES (1) ES8705896A1 (es)
GR (1) GR860231B (es)
IE (1) IE860271L (es)
PT (1) PT81941B (es)
ZA (1) ZA86702B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4584284A (en) * 1985-01-31 1986-04-22 Ortho Pharmaceutical Corporation Bursopoietin
US4866121A (en) * 1985-01-31 1989-09-12 Ortho Pharmaceutical Corporation B cell differentiating peptides and conjugates thereof
US5120831A (en) * 1985-02-08 1992-06-09 Procyte Corporation Metal-peptide compositions
US4994554A (en) * 1988-05-11 1991-02-19 Immunobiology Research Institute, Inc. Probursin
US5023237A (en) * 1989-08-30 1991-06-11 Procyte Corporation Methods and compositions for healing ulcers
US5386012A (en) * 1990-02-06 1995-01-31 Strid; Lars Growth factor in connection with artificial implants
AU6770794A (en) * 1993-04-23 1994-11-21 Herbert J. Evans Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5952465A (en) * 1993-04-23 1999-09-14 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5928896A (en) * 1993-04-23 1999-07-27 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US6258550B1 (en) 1993-04-23 2001-07-10 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein-protein interaction site
US5965698A (en) * 1993-04-23 1999-10-12 Virginia Commonwealth University Polypeptides that include conformation-constraining groups which flank a protein--protein interaction site
US6084066A (en) * 1993-10-29 2000-07-04 Virginia Commonwealth University Polypetides that include conformation-constraining groups which flank a protein-protein interaction site
AUPO161196A0 (en) * 1996-08-13 1996-09-05 Commonwealth Scientific And Industrial Research Organisation Novel compounds
WO2000018885A1 (en) 1998-09-29 2000-04-06 Gamida Cell Ltd. Methods of controlling proliferation and differentiation of stem and progenitor cells
US8466109B2 (en) * 1998-10-05 2013-06-18 Laboratoires Expanscience Cosmetic method for preventing and/or treating skin stretchmarks, and use in dermatology
RU2157234C1 (ru) * 1999-10-08 2000-10-10 Лебедев Василий Вячеславович Средство для лечения иммунодефицитных состояний
IL152904A0 (en) 2002-01-24 2003-06-24 Gamida Cell Ltd Utilization of retinoid and vitamin d receptor antagonists for expansion of renewable stem cell populations
CN100360552C (zh) * 2005-05-19 2008-01-09 四川键宇胚胎工程有限公司 一种法氏囊素三肽合成方法
CA2876021C (en) * 2012-07-10 2020-09-22 Xpd Holdings, Llc Stabilized multi-functional antioxidant compounds and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215112A (en) * 1979-03-14 1980-07-29 Ortho Pharmaceutical Corporation Tripeptides and methods
WO1986004334A1 (en) * 1985-01-18 1986-07-31 MERCK Patent Gesellschaft mit beschränkter Haftung Immunoregulatory peptides
US4584284A (en) * 1985-01-31 1986-04-22 Ortho Pharmaceutical Corporation Bursopoietin

Also Published As

Publication number Publication date
JPS61218598A (ja) 1986-09-29
CA1276398C (en) 1990-11-13
ZA86702B (en) 1987-08-26
PT81941A (en) 1986-02-01
ATE71953T1 (de) 1992-02-15
ES551399A0 (es) 1987-05-16
EP0190048A2 (en) 1986-08-06
PT81941B (pt) 1988-05-27
DK47686A (da) 1986-08-01
AU593231B2 (en) 1990-02-08
DE3683507D1 (de) 1992-03-05
US4584284A (en) 1986-04-22
IE860271L (en) 1986-07-31
AU5273786A (en) 1986-08-07
EP0190048A3 (en) 1988-08-03
EP0190048B1 (en) 1992-01-22
GR860231B (en) 1986-05-28
US4783442A (en) 1988-11-08
DK47686D0 (da) 1986-01-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203