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Laboratorios Salvat SA
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Laboratorios Salvat SA
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Publication date
Priority claimed from IT8320235Aexternal-prioritypatent/IT1212722B/en
Application filed by Laboratorios Salvat SAfiledCriticalLaboratorios Salvat SA
Priority to ES550380ApriorityCriticalpatent/ES8704923A3/en
Publication of ES550380A0publicationCriticalpatent/ES550380A0/en
Publication of ES8704923A3publicationCriticalpatent/ES8704923A3/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
The deriv. of formula (I) for use as an anti-inflammatory agent similar to aspirin but less gastro-lesive, is made by reacting thiophene 2-carboxylic acid chloride with salicylic acid in presence of an organic base, e.g. triethylamine or pyridine, and in an inert solvent.
2-ALKYL OR -ARALKYLTIO-1-CYCLOALKEN-1-CARBOXAMIDES AND THEIR SULPHOXIDES, SET FOR THEIR PREPARATION AND THEIR USE FOR THE SYNTHESIS OF TRI- AND 4,5-TETRAMETHYLENE-4-ISOTIAZE