ES8703439A1 - Procedimiento para preparar nuevas 1-ariloxipropanolaminas - Google Patents

Procedimiento para preparar nuevas 1-ariloxipropanolaminas

Info

Publication number
ES8703439A1
ES8703439A1 ES553571A ES553571A ES8703439A1 ES 8703439 A1 ES8703439 A1 ES 8703439A1 ES 553571 A ES553571 A ES 553571A ES 553571 A ES553571 A ES 553571A ES 8703439 A1 ES8703439 A1 ES 8703439A1
Authority
ES
Spain
Prior art keywords
group
hydrogen
lower alkyl
halogen atom
lower alkoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES553571A
Other languages
English (en)
Other versions
ES553571A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES553571A0 publication Critical patent/ES553571A0/es
Publication of ES8703439A1 publication Critical patent/ES8703439A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/15—Six-membered rings
    • C07D285/16—Thiadiazines; Hydrogenated thiadiazines
    • C07D285/18—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines
    • C07D285/20—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems
    • C07D285/22—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D285/24—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom
    • C07D285/26—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals
    • C07D285/30—1,2,4-Thiadiazines; Hydrogenated 1,2,4-thiadiazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with oxygen atoms directly attached to the ring sulfur atom substituted in position 6 or 7 by sulfamoyl or substituted sulfamoyl radicals with hydrocarbon radicals, substituted by hetero atoms, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

PROCEDIMIENTO PARA OBTENER 1-ARILOXIPROPANOLAMINAS. CONSISTENTE EN: HACER REACCIONAR UN COMPUESTO DE FORMULA (IV) CON UN COMPUESTO DE FORMULA (V), A TEMPERATURAS ENTRE LA AMBIENTE Y LA DE EBULLICION DE LA MEZCLA DE REACCION, ESPECIALMENTE ENTRE 40 Y 80JC, EN DISOLVENTES POLARES MATNOL, PROPANOL Y OTROS, Y COMO FIJADORES DE ACIDOS SALES COMO EL BICARBONATO SODICO O POTASICO, PARA OBTENER LOS COMPUESTOS DE FORMULA (I). SIENDO: R1 F H O HALOGENO, UN GRUPO ALQUILO INFERIOR, ALCOXI INFERIOR U OTROS; R2 F H, HALOGENO, UN GRUPO CIANO Y OTROS; R3 F H, HALOGENO, UN GRUPO ALQUILO INFERIOR O ALCOXI INFERIOR; R4 F, H OUN GRUPO ALQUILO INFERIOR; R5, UN ATOMO DE CLORO O UN GRUPO TRIFLUOROMETILO; X, UN GRUPO ALQUILENO; E Y ES CL, BR O UN RADICAL DE ACIDO SULFONICO. APLICABLES EN MEDICINA EN EL TRATAMIENTO DE LA HIPERTENSION.
ES553571A 1984-07-25 1986-04-01 Procedimiento para preparar nuevas 1-ariloxipropanolaminas Expired ES8703439A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843427309 DE3427309A1 (de) 1984-07-25 1984-07-25 Neue 1-aryloxypropanolamine, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
ES553571A0 ES553571A0 (es) 1987-02-16
ES8703439A1 true ES8703439A1 (es) 1987-02-16

Family

ID=6241461

Family Applications (3)

Application Number Title Priority Date Filing Date
ES545533A Expired ES8609291A1 (es) 1984-07-25 1985-07-24 Procedimiento para preparar nuevas 1-ariloxipropanolaminas
ES553572A Expired ES8703440A1 (es) 1984-07-25 1986-04-01 Procedimiento para preparar nuevas 1-ariloxipropanolaminas
ES553571A Expired ES8703439A1 (es) 1984-07-25 1986-04-01 Procedimiento para preparar nuevas 1-ariloxipropanolaminas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES545533A Expired ES8609291A1 (es) 1984-07-25 1985-07-24 Procedimiento para preparar nuevas 1-ariloxipropanolaminas
ES553572A Expired ES8703440A1 (es) 1984-07-25 1986-04-01 Procedimiento para preparar nuevas 1-ariloxipropanolaminas

Country Status (5)

Country Link
US (1) US4594344A (es)
EP (1) EP0169495A3 (es)
JP (1) JPS6144885A (es)
DE (1) DE3427309A1 (es)
ES (3) ES8609291A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3632544A1 (de) * 1986-09-25 1988-04-07 Boehringer Ingelheim Kg Neue aryloxy-aminoalkane, ihre herstellung und verwendung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3110716A (en) * 1958-02-17 1963-11-12 Pfizer & Co C Derivatives of 3, 6-disubstituted-7-sulfamylbenzothiadiazine dioxides
GB1455116A (en) * 1972-12-15 1976-11-10 Ici Ltd Pharmaceutical compositions
EP0105732A3 (en) * 1982-10-01 1985-09-04 Beecham Group Plc Histamine h2 receptor antagonists of the benzisothiazole amino and benzthiadiazine amino series

Also Published As

Publication number Publication date
JPS6144885A (ja) 1986-03-04
US4594344A (en) 1986-06-10
EP0169495A3 (de) 1986-11-26
EP0169495A2 (de) 1986-01-29
ES8609291A1 (es) 1986-07-16
ES553571A0 (es) 1987-02-16
ES553572A0 (es) 1987-02-16
ES8703440A1 (es) 1987-02-16
DE3427309A1 (de) 1986-01-30
ES545533A0 (es) 1986-07-16

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