ES8702877A1 - Benzoic acid derivatives and process for their preparation - Google Patents

Benzoic acid derivatives and process for their preparation

Info

Publication number
ES8702877A1
ES8702877A1 ES548360A ES548360A ES8702877A1 ES 8702877 A1 ES8702877 A1 ES 8702877A1 ES 548360 A ES548360 A ES 548360A ES 548360 A ES548360 A ES 548360A ES 8702877 A1 ES8702877 A1 ES 8702877A1
Authority
ES
Spain
Prior art keywords
benzoic acid
acid derivatives
preparation
asthmatic
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES548360A
Other languages
Spanish (es)
Other versions
ES548360A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES548360A0 publication Critical patent/ES548360A0/en
Publication of ES8702877A1 publication Critical patent/ES8702877A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/03—Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
    • C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Benzoic acid derivatives represented by general formula (I) (wherein R<1> represents lower alkyl, R<2> represents optionally protected carboxy, and X represents halogen) or salts thereof, particularly those wherein R<2> represents a carboxy group protected by a group represented by formula (II) (wherein n represents an integer of 2 to 4, R<3> and R<4> may be the same or different and each represents hydrogen or alkyl or, when taken together with the adjacent nitrogen atom, R<3> and R<4> may form a heterocyclic group) or salts thereof, have excellent anti-asthmatic and anti-inflammatory effects, thus being utilized as anti-asthmatic and anti-inflammatory agents for mammals.
ES548360A 1984-10-30 1985-10-30 Benzoic acid derivatives and process for their preparation Expired ES8702877A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP1984/000520 WO1986002636A1 (en) 1984-10-30 1984-10-30 Benzoic acid derivatives and process for their preparation

Publications (2)

Publication Number Publication Date
ES548360A0 ES548360A0 (en) 1987-01-16
ES8702877A1 true ES8702877A1 (en) 1987-01-16

Family

ID=13818454

Family Applications (1)

Application Number Title Priority Date Filing Date
ES548360A Expired ES8702877A1 (en) 1984-10-30 1985-10-30 Benzoic acid derivatives and process for their preparation

Country Status (7)

Country Link
JP (1) JPS61267539A (en)
KR (1) KR870003047A (en)
AU (1) AU4900085A (en)
ES (1) ES8702877A1 (en)
SU (1) SU1454247A3 (en)
WO (1) WO1986002636A1 (en)
ZA (1) ZA858341B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683242A (en) * 1985-10-28 1987-07-28 A. H. Robins Company, Incorporated Transdermal treatment for pain and inflammation with 2-amino-3-aroylbenzeneacetic acids, salts and esters

Also Published As

Publication number Publication date
WO1986002636A1 (en) 1986-05-09
AU4900085A (en) 1986-05-08
SU1454247A3 (en) 1989-01-23
ES548360A0 (en) 1987-01-16
ZA858341B (en) 1987-06-24
JPS61267539A (en) 1986-11-27
KR870003047A (en) 1987-04-14

Similar Documents

Publication Publication Date Title
ES8506677A1 (en) Novel 8-chloro-1,5-benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions.
EP0163599A3 (en) Pyrimidopyrimidine derivatives, processes for producing them, pharmaceutical compositions containing them and their use as anti-allergic agents
ES8400737A1 (en) New herbicidal nicotinamide derivatives.
AU589427B2 (en) Pyridonecarboxylic acid derivatives and process for their preparation
AU537028B2 (en) Imidazole derivatives
ES8802148A1 (en) Quinolonecarboxylic acid derivatives.
ES8404360A1 (en) 7-Acylamino-3-cephem-4-carboxylic acid derivatives, processes for the preparation of the same and pharmaceutical composition comprising the same.
ES8800122A1 (en) Indene and naphthalene derivatives.
ES8604218A1 (en) Benzoquinolizines.
ES8702877A1 (en) Benzoic acid derivatives and process for their preparation
ES8607967A1 (en) Thiazolylacetic acid derivatives and their preparation.
ES8707963A1 (en) Antibacterial 7-oxo-4-thia-1-azabicyclo not 3,2,0 hept-2-ene derivatives
IE792067L (en) Azatricyclic compounds
ES464865A1 (en) Basically alkylated dithiosalicyclic acid amides and their use as medicaments
ES8704947A1 (en) Imidazopyridayine derivatives having antiviral activity
ES8307812A1 (en) Beta-lactam antibacterial agents, their preparation and use.