ES8702790A1 - Un metodo para preparar una composicion de anticuerpos monoclonales estable termicamente. - Google Patents
Un metodo para preparar una composicion de anticuerpos monoclonales estable termicamente.Info
- Publication number
- ES8702790A1 ES8702790A1 ES545975A ES545975A ES8702790A1 ES 8702790 A1 ES8702790 A1 ES 8702790A1 ES 545975 A ES545975 A ES 545975A ES 545975 A ES545975 A ES 545975A ES 8702790 A1 ES8702790 A1 ES 8702790A1
- Authority
- ES
- Spain
- Prior art keywords
- monoclonal antibody
- antibody stabilization
- stabilization
- solution containing
- monoclonal antibodies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000006641 stabilisation Effects 0.000 title abstract 2
- 238000011105 stabilization Methods 0.000 title abstract 2
- 108010058846 Ovalbumin Proteins 0.000 abstract 1
- 229940092253 ovalbumin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5306—Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/639,156 US4650772A (en) | 1984-08-09 | 1984-08-09 | Monoclonal antibody stabilization |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8702790A1 true ES8702790A1 (es) | 1987-01-16 |
| ES545975A0 ES545975A0 (es) | 1987-01-16 |
Family
ID=24562959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES545975A Expired ES8702790A1 (es) | 1984-08-09 | 1985-08-07 | Un metodo para preparar una composicion de anticuerpos monoclonales estable termicamente. |
Country Status (15)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ217844A (en) * | 1985-10-11 | 1989-10-27 | Sumitomo Pharma | A sustained release pharmaceutical composition containing silicone elastomer and an albumin |
| US5237054A (en) * | 1987-02-20 | 1993-08-17 | Akzo Pharma | Stabilized aqueous composition containing antibodies |
| EP0280358B1 (en) * | 1987-02-20 | 1992-12-30 | Akzo N.V. | Stabilized aqueous composition containing antibodies |
| DE3825429C2 (de) * | 1988-07-27 | 1994-02-10 | Biotest Pharma Gmbh | Verfahren zur Herstellung eines intravenös verabreichbaren polyklonalen Immunglobulin-Präparates mit hohem IgM-Gehalt |
| JP2627681B2 (ja) * | 1990-07-18 | 1997-07-09 | 同仁医薬化工株式会社 | マイコプラズマ・ニューモニエ診断用試薬 |
| EP0539584B1 (en) * | 1990-07-18 | 1996-11-20 | Dojin Iyaku-Kako Co., Ltd. | Reagent for diagnosing mycoplasma pneumoniae |
| JPH0565233A (ja) * | 1991-03-08 | 1993-03-19 | Mitsui Toatsu Chem Inc | モノクローナル抗体含有凍結乾燥製剤 |
| JP2553445B2 (ja) * | 1992-12-17 | 1996-11-13 | 同仁医薬化工株式会社 | 抗体の安定化方法 |
| EP0852951A1 (de) | 1996-11-19 | 1998-07-15 | Roche Diagnostics GmbH | Stabile lyophilisierte pharmazeutische Zubereitungen von mono- oder polyklonalen Antikörpern |
| US8858935B2 (en) | 2005-05-19 | 2014-10-14 | Amgen Inc. | Compositions and methods for increasing the stability of antibodies |
| EP2529228A4 (en) * | 2010-01-26 | 2013-09-04 | Obschestvo S Ogranichennoi Otvetstvennostyu N Proizv Materia Medika Kholding Fa | METHOD FOR DETERMINING THE LEVEL OF AUTOANTIBODIES BY IMMUNOENZYMATIC TESTING |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5816471B2 (ja) * | 1977-11-29 | 1983-03-31 | 持田製薬株式会社 | 免疫化学的測定試薬の安定化剤 |
| US4444880A (en) * | 1982-07-27 | 1984-04-24 | Syva Company | Periodate removal of ascorbate interference in dipsticks for immunoassays |
| US4439421A (en) * | 1982-08-30 | 1984-03-27 | Baxter Travenol Laboratories, Inc. | Stabilized gamma globulin concentrate |
| US4482483A (en) * | 1983-04-06 | 1984-11-13 | Armour Pharmceutical Company | Composition of intravenous immune globulin |
-
1984
- 1984-08-09 US US06/639,156 patent/US4650772A/en not_active Expired - Fee Related
-
1985
- 1985-07-08 CA CA000486466A patent/CA1238284A/en not_active Expired
- 1985-07-09 NZ NZ212694A patent/NZ212694A/en unknown
- 1985-07-10 IL IL75762A patent/IL75762A/xx not_active IP Right Cessation
- 1985-07-11 ZA ZA855248A patent/ZA855248B/xx unknown
- 1985-07-22 DK DK333185A patent/DK333185A/da not_active Application Discontinuation
- 1985-07-25 AU AU45369/85A patent/AU592952B2/en not_active Ceased
- 1985-07-25 AT AT85109277T patent/ATE57021T1/de not_active IP Right Cessation
- 1985-07-25 EP EP85109277A patent/EP0170983B1/en not_active Expired - Lifetime
- 1985-07-25 DE DE8585109277T patent/DE3579868D1/de not_active Expired - Fee Related
- 1985-08-06 GR GR851926A patent/GR851926B/el unknown
- 1985-08-07 ES ES545975A patent/ES8702790A1/es not_active Expired
- 1985-08-08 IE IE196485A patent/IE58626B1/en not_active IP Right Cessation
- 1985-08-08 KR KR1019850005717A patent/KR900002652B1/ko not_active Expired
- 1985-08-08 JP JP60173351A patent/JPH0699325B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE3579868D1 (de) | 1990-10-31 |
| GR851926B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1985-12-09 |
| KR900002652B1 (ko) | 1990-04-21 |
| IE58626B1 (en) | 1993-10-20 |
| EP0170983B1 (en) | 1990-09-26 |
| JPS6176423A (ja) | 1986-04-18 |
| US4650772A (en) | 1987-03-17 |
| EP0170983A3 (en) | 1988-01-27 |
| IE851964L (en) | 1986-02-09 |
| IL75762A (en) | 1989-10-31 |
| ATE57021T1 (de) | 1990-10-15 |
| ES545975A0 (es) | 1987-01-16 |
| ZA855248B (en) | 1986-02-26 |
| AU4536985A (en) | 1986-02-13 |
| AU592952B2 (en) | 1990-02-01 |
| KR860001594A (ko) | 1986-03-20 |
| EP0170983A2 (en) | 1986-02-12 |
| CA1238284A (en) | 1988-06-21 |
| NZ212694A (en) | 1988-05-30 |
| IL75762A0 (en) | 1985-11-29 |
| DK333185D0 (da) | 1985-07-22 |
| DK333185A (da) | 1986-02-10 |
| JPH0699325B2 (ja) | 1994-12-07 |
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