ES8700255A1 - Un procedimiento para la preparacion de 2-bencil-4-(4-piridil)-tiazoles. - Google Patents

Un procedimiento para la preparacion de 2-bencil-4-(4-piridil)-tiazoles.

Info

Publication number
ES8700255A1
ES8700255A1 ES545439A ES545439A ES8700255A1 ES 8700255 A1 ES8700255 A1 ES 8700255A1 ES 545439 A ES545439 A ES 545439A ES 545439 A ES545439 A ES 545439A ES 8700255 A1 ES8700255 A1 ES 8700255A1
Authority
ES
Spain
Prior art keywords
benzyl
thiazole
pyriol
morpholino
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES545439A
Other languages
English (en)
Spanish (es)
Other versions
ES545439A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES545439A0 publication Critical patent/ES545439A0/es
Publication of ES8700255A1 publication Critical patent/ES8700255A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
ES545439A 1984-07-25 1985-07-22 Un procedimiento para la preparacion de 2-bencil-4-(4-piridil)-tiazoles. Expired ES8700255A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/634,094 US4697012A (en) 1984-07-25 1984-07-25 Morpholino pyridyl thiazole compound

Publications (2)

Publication Number Publication Date
ES545439A0 ES545439A0 (es) 1986-10-01
ES8700255A1 true ES8700255A1 (es) 1986-10-01

Family

ID=24542414

Family Applications (1)

Application Number Title Priority Date Filing Date
ES545439A Expired ES8700255A1 (es) 1984-07-25 1985-07-22 Un procedimiento para la preparacion de 2-bencil-4-(4-piridil)-tiazoles.

Country Status (12)

Country Link
US (1) US4697012A (US20100223739A1-20100909-C00005.png)
EP (1) EP0169502B1 (US20100223739A1-20100909-C00005.png)
JP (1) JPS6137784A (US20100223739A1-20100909-C00005.png)
KR (1) KR860001105A (US20100223739A1-20100909-C00005.png)
AU (1) AU575666B2 (US20100223739A1-20100909-C00005.png)
DE (1) DE3580317D1 (US20100223739A1-20100909-C00005.png)
DK (1) DK336685A (US20100223739A1-20100909-C00005.png)
ES (1) ES8700255A1 (US20100223739A1-20100909-C00005.png)
GR (1) GR851809B (US20100223739A1-20100909-C00005.png)
IL (1) IL75823A0 (US20100223739A1-20100909-C00005.png)
PT (1) PT80833B (US20100223739A1-20100909-C00005.png)
ZA (1) ZA855581B (US20100223739A1-20100909-C00005.png)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0149884B1 (en) * 1983-09-09 1992-12-16 Takeda Chemical Industries, Ltd. 5-pyridyl-1,3-thiazole derivatives, their production and use
GB9201692D0 (en) * 1992-01-27 1992-03-11 Smithkline Beecham Intercredit Compounds
HUP9801057A3 (en) * 1995-05-26 2000-06-28 Bayer Ag Pyridyl-thiazoles and their use to protect plants against infections by micro-organisms
JP4662764B2 (ja) 2002-06-14 2011-03-30 メルク セローノ ソシエテ アノニム アゾールメチリデンシアニド誘導体およびそれらのタンパク質キナーゼモジュレーターとしての使用
SA04250288B1 (ar) * 2003-09-19 2008-07-19 سولفاي فارماسوتيكالز بي . في مشتقات ثيازول thiazole كمعدلات لمستقبل المكونات الكيميائية للقنب cannabinoid
US7294640B2 (en) 2004-02-06 2007-11-13 Merck & Co., Inc. Mitotic kinesin inhibitors
EP2616441B1 (en) * 2010-09-17 2019-08-07 Purdue Pharma L.P. Pyridine compounds and the uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1112128A (en) * 1965-12-22 1968-05-01 Bellon Labor Sa Roger New thiazolyl-diphenylmethane derivatives
IL28803A (en) * 1966-11-18 1974-05-16 Wyeth John & Brother Ltd Oxazole and thiazole compounds,their preparation and pharmaceutical compositions containing them
CA962269A (en) * 1971-05-05 1975-02-04 Robert E. Grahame (Jr.) Thiazoles, and their use as insecticides
US4153703A (en) * 1977-06-30 1979-05-08 Uniroyal, Inc. Method of controlling insects and acarids with certain aryl-substituted thiazoles
EP0149884B1 (en) * 1983-09-09 1992-12-16 Takeda Chemical Industries, Ltd. 5-pyridyl-1,3-thiazole derivatives, their production and use

Also Published As

Publication number Publication date
EP0169502B1 (en) 1990-10-31
DE3580317D1 (en) 1990-12-13
DK336685A (da) 1986-01-26
ZA855581B (en) 1986-03-26
IL75823A0 (en) 1985-11-29
EP0169502A3 (en) 1987-02-25
ES545439A0 (es) 1986-10-01
US4697012A (en) 1987-09-29
JPS6137784A (ja) 1986-02-22
AU575666B2 (en) 1988-08-04
PT80833B (en) 1987-05-27
DK336685D0 (da) 1985-07-24
AU4532085A (en) 1986-01-30
KR860001105A (ko) 1986-02-22
EP0169502A2 (en) 1986-01-29
GR851809B (US20100223739A1-20100909-C00005.png) 1985-11-26
PT80833A (en) 1985-08-01

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