ES8608482A1 - Un procedimiento para preparar bisarilamidas de n,n'-di(1 aminoalquil-2) alquilendiaminas. - Google Patents
Un procedimiento para preparar bisarilamidas de n,n'-di(1 aminoalquil-2) alquilendiaminas.Info
- Publication number
- ES8608482A1 ES8608482A1 ES545622A ES545622A ES8608482A1 ES 8608482 A1 ES8608482 A1 ES 8608482A1 ES 545622 A ES545622 A ES 545622A ES 545622 A ES545622 A ES 545622A ES 8608482 A1 ES8608482 A1 ES 8608482A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- phenyl
- hydrogen
- optionally substituted
- polymethylene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000005792 cardiovascular activity Effects 0.000 title abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 title abstract 2
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 7
- 229910052739 hydrogen Inorganic materials 0.000 abstract 5
- 239000001257 hydrogen Substances 0.000 abstract 5
- -1 cyano, hydroxy Chemical group 0.000 abstract 4
- 150000002431 hydrogen Chemical group 0.000 abstract 3
- 125000000229 (C1-C4)alkoxy group Chemical group 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- 150000003573 thiols Chemical group 0.000 abstract 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 206010002383 Angina Pectoris Diseases 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000002213 calciumantagonistic effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000006413 ring segment Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/56—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having carbon atoms of carboxamide groups bound to carbon atoms of carboxyl groups, e.g. oxamides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB848419103A GB8419103D0 (en) | 1984-07-26 | 1984-07-26 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES545622A0 ES545622A0 (es) | 1986-06-16 |
| ES8608482A1 true ES8608482A1 (es) | 1986-06-16 |
Family
ID=10564506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES545622A Expired ES8608482A1 (es) | 1984-07-26 | 1985-07-26 | Un procedimiento para preparar bisarilamidas de n,n'-di(1 aminoalquil-2) alquilendiaminas. |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0174085A3 (en, 2012) |
| JP (1) | JPS6147452A (en, 2012) |
| AU (1) | AU4534285A (en, 2012) |
| DK (1) | DK340385A (en, 2012) |
| ES (1) | ES8608482A1 (en, 2012) |
| GB (1) | GB8419103D0 (en, 2012) |
| GR (1) | GR851834B (en, 2012) |
| PT (1) | PT80868A (en, 2012) |
| ZA (1) | ZA855579B (en, 2012) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ223340A (en) * | 1987-02-03 | 1991-03-26 | Merrell Dow Pharma | Polyamine derivatives and pharmaceutical compositions |
| ZA887410B (en) * | 1987-10-08 | 1989-06-28 | Merrell Dow Pharma | Polyamine derivatives as antineoplastic agents |
| WO1989007098A1 (en) * | 1988-02-08 | 1989-08-10 | The Trustees Of Columbia University In The City Of | Butyrl-tyrosinyl spermine, analogs thereof and methods of preparing and using same |
| GB8820442D0 (en) * | 1988-08-30 | 1988-09-28 | Usherwood P N R | Therapeutic polyamine amides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1470357A1 (de) * | 1964-01-28 | 1969-06-12 | Thomae Gmbh Dr K | Verfahren zur Herstellung von neuen acylierten Piperidin-(4)-aminen |
| JPS4939679B1 (en, 2012) * | 1969-06-30 | 1974-10-28 | ||
| JPS497134B1 (en, 2012) * | 1969-12-13 | 1974-02-19 | ||
| CA1183847A (en) * | 1981-10-01 | 1985-03-12 | Georges Van Daele | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
| DE3242344A1 (de) * | 1982-11-16 | 1984-05-17 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue alkylendiaminoderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel |
-
1984
- 1984-07-26 GB GB848419103A patent/GB8419103D0/en active Pending
-
1985
- 1985-07-24 ZA ZA855579A patent/ZA855579B/xx unknown
- 1985-07-24 GR GR851834A patent/GR851834B/el unknown
- 1985-07-25 DK DK340385A patent/DK340385A/da not_active Application Discontinuation
- 1985-07-25 EP EP85305285A patent/EP0174085A3/en not_active Withdrawn
- 1985-07-25 PT PT80868A patent/PT80868A/pt unknown
- 1985-07-25 AU AU45342/85A patent/AU4534285A/en not_active Abandoned
- 1985-07-26 ES ES545622A patent/ES8608482A1/es not_active Expired
- 1985-07-26 JP JP60165628A patent/JPS6147452A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| DK340385A (da) | 1986-01-27 |
| JPS6147452A (ja) | 1986-03-07 |
| DK340385D0 (da) | 1985-07-25 |
| EP0174085A2 (en) | 1986-03-12 |
| GR851834B (en, 2012) | 1985-12-02 |
| ES545622A0 (es) | 1986-06-16 |
| PT80868A (en) | 1985-08-01 |
| EP0174085A3 (en) | 1987-10-14 |
| AU4534285A (en) | 1986-01-30 |
| ZA855579B (en) | 1986-09-24 |
| GB8419103D0 (en) | 1984-08-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB8823731D0 (en) | Biologically active compounds | |
| HUP0002476A2 (hu) | Aminvegyületek, előállításuk és alkalmazásuk | |
| YU53700A (sh) | Biciklo(2.2.1.) heptani i srodna jedinjenja | |
| GR3036455T3 (en) | Atherosclerosis treatment | |
| IL112462A0 (en) | Substituted aromatic compounds | |
| IL113599A (en) | 5-aryl pyrimidines, their preparation and pharmaceutical compositions containing them | |
| ATE358122T1 (de) | Inhibitoren der tnf-alpha bildung zur behandlung von autoimmunerkrankungen | |
| PH25859A (en) | Composition for treatment of ischemic disorder | |
| MXPA05007494A (es) | Nuevos compuestos. | |
| EP0518819A3 (en) | Amidino compounds, their manufacture and use as medicament | |
| HRP20030778B1 (hr) | Bifenilkarboksamidi koji snižavaju lipide | |
| EP0368933A4 (en) | COMPOSITIONS COMPRISING AZACYCLOALCANES SUBSTITUTED BY 1-OXO-HYDROCARBYL OR THIOHYDROCARBYL. | |
| DK183789A (da) | 2-alkyl-3-benzoylbenzofuraner og laegemidler indeholdende disse | |
| ES8608482A1 (es) | Un procedimiento para preparar bisarilamidas de n,n'-di(1 aminoalquil-2) alquilendiaminas. | |
| ZA885241B (en) | Biologically active compounds | |
| NO961077L (no) | Substituerte benzoltienylpiperaziner, deres anvendelse som medikamenter og fremgangsmåter for fremstilling | |
| GR3002594T3 (en) | Aromatic thioethers | |
| TW366283B (en) | Compounds for treatment of arrhythmia | |
| JPS56103140A (en) | Novel ethers* manufacture and medicinal composition containing them | |
| DK60793D0 (da) | Kemiske forbindelser, deres fremstilling og anvendelse | |
| ES8802029A1 (es) | Procedimiento para preparar dihidropiridinas. |