ES8606274A1 - Procedimiento para la obtencion de piperidinas sustituidas - Google Patents
Procedimiento para la obtencion de piperidinas sustituidasInfo
- Publication number
- ES8606274A1 ES8606274A1 ES548950A ES548950A ES8606274A1 ES 8606274 A1 ES8606274 A1 ES 8606274A1 ES 548950 A ES548950 A ES 548950A ES 548950 A ES548950 A ES 548950A ES 8606274 A1 ES8606274 A1 ES 8606274A1
- Authority
- ES
- Spain
- Prior art keywords
- preparation
- substituted piperidines
- substituted
- piperidines
- glutardialdehyde
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/023—Preparation; Separation; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/12—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with only hydrogen atoms attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE PIPERIDINAS SUSTITUIDAS. COMPRENDE: A) MEZCLAR AL GLUTARDIALDEHIDO SUSTITUIDO EN POSICION 2 Y 3 D.F. (II) CON DIOXANO O TETRAHIDRO-FURANO; B) DILUIR AL COMPONENTE DE AMINA D.F. (H2N-R3) EN ALCOHOL (METANOL O ETANOL) Y C) HACER REACCIONAR A LA MEZCLA DE A) CON LA DILUCION DE B) Y CON H2, EN PRESENCIA DE UN CATALIZADOR COMO NI RANEY, PLATINO, O RUTENIO, A UNA TEMPERATURA ENTRE 80 Y 110JC Y A UNA PRESION ENTRE 100 Y 300 BAR, PARA OBTENER PIPERIDINAS SUSTITUIDAS EN POSICION 3 Y 4 D.F. (I). SIENDO: D.F. DE FORMULA; R1 Y R2 IDENTICOS Y DIFERENTES Y SIGNIFICAN ALQUILO LINEAL O RAMIFICADO, CICLOALQUILO, ARILO, ARALQUILO Y OTROS Y R3 ALQUILO DE C 1 A 4 O HIDROGENO. SE UTILIZAN EN LAS SINTESIS DE PRINCIPIOS ACTIVOS FOTOSANITARIOS Y COMO INHIBIDORES DE LA AGREGACION DE TROMBOCITOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19843441929 DE3441929A1 (de) | 1984-11-16 | 1984-11-16 | Verfahren zur herstellung von substituierten piperidinen |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8606274A1 true ES8606274A1 (es) | 1986-04-01 |
ES548950A0 ES548950A0 (es) | 1986-04-01 |
Family
ID=6250470
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES548950A Expired ES8606274A1 (es) | 1984-11-16 | 1985-11-15 | Procedimiento para la obtencion de piperidinas sustituidas |
Country Status (11)
Country | Link |
---|---|
US (1) | US4656282A (es) |
EP (1) | EP0181618B1 (es) |
JP (1) | JPS61122268A (es) |
AT (1) | ATE74129T1 (es) |
CA (1) | CA1264752A (es) |
DE (2) | DE3441929A1 (es) |
DK (1) | DK173734B1 (es) |
ES (1) | ES8606274A1 (es) |
HU (1) | HU194169B (es) |
IL (1) | IL76957A (es) |
ZA (1) | ZA858770B (es) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE912759A1 (en) * | 1990-08-06 | 1992-02-12 | Smith Kline French Lab | Compounds |
GB9100505D0 (en) * | 1991-01-10 | 1991-02-20 | Shell Int Research | Piperidine derivatives |
CA2284732C (en) | 1997-04-07 | 2008-06-17 | Georgetown University | Analogs of cocaine |
JP2012512172A (ja) * | 2008-12-15 | 2012-05-31 | タイゲン バイオテクノロジー カンパニー,リミテッド | ピペリジン誘導体の立体選択的合成 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB726378A (en) * | 1952-07-03 | 1955-03-16 | Basf Ag | Improvements in the production of compounds of the pyridine series |
-
1984
- 1984-11-16 DE DE19843441929 patent/DE3441929A1/de not_active Withdrawn
-
1985
- 1985-11-01 CA CA000494392A patent/CA1264752A/en not_active Expired - Lifetime
- 1985-11-04 US US06/794,744 patent/US4656282A/en not_active Expired - Lifetime
- 1985-11-05 IL IL76957A patent/IL76957A/xx not_active IP Right Cessation
- 1985-11-08 DE DE8585114232T patent/DE3585721D1/de not_active Expired - Lifetime
- 1985-11-08 EP EP85114232A patent/EP0181618B1/de not_active Expired - Lifetime
- 1985-11-08 AT AT85114232T patent/ATE74129T1/de not_active IP Right Cessation
- 1985-11-14 JP JP60253897A patent/JPS61122268A/ja active Pending
- 1985-11-15 ES ES548950A patent/ES8606274A1/es not_active Expired
- 1985-11-15 ZA ZA858770A patent/ZA858770B/xx unknown
- 1985-11-15 DK DK198505278A patent/DK173734B1/da not_active IP Right Cessation
- 1985-11-15 HU HU854372A patent/HU194169B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US4656282A (en) | 1987-04-07 |
HU194169B (en) | 1988-01-28 |
DE3585721D1 (de) | 1992-04-30 |
DK527885A (da) | 1986-05-17 |
DE3441929A1 (de) | 1986-05-28 |
EP0181618A3 (en) | 1988-06-22 |
ES548950A0 (es) | 1986-04-01 |
ATE74129T1 (de) | 1992-04-15 |
EP0181618A2 (de) | 1986-05-21 |
DK527885D0 (da) | 1985-11-15 |
CA1264752A (en) | 1990-01-23 |
DK173734B1 (da) | 2001-08-13 |
HUT40078A (en) | 1986-11-28 |
ZA858770B (en) | 1986-08-27 |
EP0181618B1 (de) | 1992-03-25 |
IL76957A (en) | 1989-01-31 |
IL76957A0 (en) | 1986-04-29 |
JPS61122268A (ja) | 1986-06-10 |
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