ES8604588A1 - Antiviral purine derivs. esp. active against herpes viruses - Google Patents
Antiviral purine derivs. esp. active against herpes virusesInfo
- Publication number
- ES8604588A1 ES8604588A1 ES526433A ES526433A ES8604588A1 ES 8604588 A1 ES8604588 A1 ES 8604588A1 ES 526433 A ES526433 A ES 526433A ES 526433 A ES526433 A ES 526433A ES 8604588 A1 ES8604588 A1 ES 8604588A1
- Authority
- ES
- Spain
- Prior art keywords
- esp
- hydroxyalkyl
- alkyl
- treatment
- derivs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Cpds. of formula (I) and their physiologically acceptable salts and esters are new (where X is O, S or a bond R' is halogen, amino or azido R2 is H, OH, alkyl or hydroxyalkyl R3 is H or alkyl R4 is OH, hydroxyalkyl, benzyloxy, phosphate or carboxypropionyloxy and R5 is H, alkyl or hydroxyalkyl). 3 cpds. are specifically claimed, e.g. 2-amino-9-(2-hydroxyethoxymethyl) -9H-purine. (I) are antiviral agents having a high level of absorption from the g.i. track. They are useful in treatment of diseases caused by e.g. herpes simplex, -raricella or -zoster, cytomegalovirus, ehpatitis B virus or Epstein-Barr virus. They may also be used for treatment or prophylaxis of papilloma or wart virus infections, and for treatment of equine rhinopneumonitis. Doses are 0.1-250, esp. 5-20 mg/kg/day, e.g. in units contg. 100-400 mg of active agent. Admin. may be enterally, parenterally or topically.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43439382A | 1982-10-14 | 1982-10-14 | |
| US43439482A | 1982-10-14 | 1982-10-14 | |
| US06/434,384 US4544634A (en) | 1982-10-14 | 1982-10-14 | Method of producing acyclovir |
| US06/434,395 US4609662A (en) | 1982-10-14 | 1982-10-14 | Method for using purine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES526433A0 ES526433A0 (en) | 1986-02-01 |
| ES8604588A1 true ES8604588A1 (en) | 1986-02-01 |
Family
ID=27503835
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES526433A Expired ES8604588A1 (en) | 1982-10-14 | 1983-10-13 | Antiviral purine derivs. esp. active against herpes viruses |
| ES533406A Expired ES8602794A1 (en) | 1982-10-14 | 1984-06-14 | Antiviral purine derivs. esp. active against herpes viruses |
| ES533405A Expired ES8603482A1 (en) | 1982-10-14 | 1984-06-14 | Antiviral purine derivs. esp. active against herpes viruses |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES533406A Expired ES8602794A1 (en) | 1982-10-14 | 1984-06-14 | Antiviral purine derivs. esp. active against herpes viruses |
| ES533405A Expired ES8603482A1 (en) | 1982-10-14 | 1984-06-14 | Antiviral purine derivs. esp. active against herpes viruses |
Country Status (3)
| Country | Link |
|---|---|
| CS (2) | CS244679B2 (en) |
| ES (3) | ES8604588A1 (en) |
| HU (1) | HU193273B (en) |
-
1983
- 1983-10-13 ES ES526433A patent/ES8604588A1/en not_active Expired
- 1983-10-13 CS CS753083A patent/CS244679B2/en unknown
- 1983-10-13 HU HU354683A patent/HU193273B/en not_active IP Right Cessation
-
1984
- 1984-06-14 ES ES533406A patent/ES8602794A1/en not_active Expired
- 1984-06-14 ES ES533405A patent/ES8603482A1/en not_active Expired
- 1984-08-21 CS CS846318A patent/CS244696B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES526433A0 (en) | 1986-02-01 |
| ES533406A0 (en) | 1985-12-01 |
| CS244679B2 (en) | 1986-08-14 |
| HU193273B (en) | 1987-09-28 |
| CS244696B2 (en) | 1986-08-14 |
| ES8602794A1 (en) | 1985-12-01 |
| ES533405A0 (en) | 1985-12-16 |
| ES8603482A1 (en) | 1985-12-16 |
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