Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Lasa Laboratorios SA
Original Assignee
Lasa Laboratorios SA
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Filing date
Publication date
Application filed by Lasa Laboratorios SAfiledCriticalLasa Laboratorios SA
Priority to ES544813ApriorityCriticalpatent/ES8604573A1/es
Publication of ES8604573A1publicationCriticalpatent/ES8604573A1/es
Publication of ES544813A0publicationCriticalpatent/ES544813A0/es
PROCEDIMIENTO PARA LA OBTENCION DE 2-IMIDAZOLINAS DE INTERES TERAPEUTICO. CONSISTE EN PARTIR DEL CORRESPONDIENTE BENZO-1,4-DIOXANO-2-CARBONITRILO, QUE POR TRATAMIENTO CON UN ACIDO FUERTE EN MEDIO ALCOHOLICO ANHIDRO SE TRANSFORMA EN UN IMINOESTER EN FORMA DE SAL DE ACIDO EMPLEADO, EL CUAL MEDIANTE UNA REACCION DE CICLACION EN MEDIO BASICO CON LA ETILENDIAMINA ADECUADAMENTE SUSTITUIDA, PERMITE OBTENER LAS 2-IMIDAZOLINAS DE FORMULA (I), DONDE R1 ES H, CH3O, HO, CL O NO2; R2 ES H, CH3, CH3CH2 O C3H7; Y R3, R4 Y R5 SON H O CH3. SON UTILIZADAS TERAPEUTICAMENTE COMO ANTIDEPRESIVOS POTENCIALES POR PRESENTAR ACTIVIDAD SOBRE LOS RECEPTORES A-ADRENERGICOS.
ES544813A1985-07-021985-07-02Procedimiento para la obtencion de 2-imidazolinas de intere-ses terapeutico
ExpiredES8604573A1
(es)