ES8604501A2 - Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines - Google Patents
Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidinesInfo
- Publication number
- ES8604501A2 ES8604501A2 ES540192A ES540192A ES8604501A2 ES 8604501 A2 ES8604501 A2 ES 8604501A2 ES 540192 A ES540192 A ES 540192A ES 540192 A ES540192 A ES 540192A ES 8604501 A2 ES8604501 A2 ES 8604501A2
- Authority
- ES
- Spain
- Prior art keywords
- formula
- obtaining
- alkyl
- sulphonamidines
- thio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Process for obtaining sulphonamidines of general formula I". Comprises preparing a compound of formula I" where R" is 2-[[[2-[(aminoiminomethyl)amino]-4- thiazolyl]methyl]thio]ethyl and R"1 is phenyl substituted by halogen, alkoxy carbonyl, dialkylamino, nitro, alkyl sulphonyl, alkyl sulphonyl amino and alkyl thio, and their therapeutically acceptable salts, by reacting an amine of formula II" where R" has the same meaning as in I" with an excess of an orthoformate of formula III in which R2 is alkyl, thus obtaining the intermediate imidate of formula IV", where B" and R2 have the same meanings as in the previous structures, which in turn is caused to react with the sulphonamide of formula V", where R"1 has the same meaning as in I", in an alkanolic medium. Useful for inhibiting acid secretion through antagonism of H-2 histamine receptors. R"-NH-CH=N-SO2-R"1(I") R"-NH2 (II") H-C(OR2)3 (III) R"-N=CH-OR2 (IV") H2N-SO2-R"1 (V")
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES540192A ES8604501A2 (en) | 1985-01-25 | 1985-01-25 | Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines |
CA000477755A CA1269382A (en) | 1984-04-18 | 1985-03-28 | Anti-ulceric sulfonamidines |
PH32140A PH21779A (en) | 1984-04-18 | 1985-04-15 | Sulfonomidines and pharmaceutical compositions containing the same |
EP85104577A EP0159012B1 (en) | 1984-04-18 | 1985-04-16 | Sulfonamidines, a process for preparing them and pharmaceutical compositions containing them |
DE8585104577T DE3568041D1 (en) | 1984-04-18 | 1985-04-16 | Sulfonamidines, a process for preparing them and pharmaceutical compositions containing them |
US06/724,784 US4728655A (en) | 1984-04-18 | 1985-04-18 | Sulfonamidines, process for the production thereof and pharmaceutical compositions containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES540192A ES8604501A2 (en) | 1985-01-25 | 1985-01-25 | Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines |
Publications (2)
Publication Number | Publication Date |
---|---|
ES540192A0 ES540192A0 (en) | 1986-02-01 |
ES8604501A2 true ES8604501A2 (en) | 1986-02-01 |
Family
ID=8488664
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES540192A Expired ES8604501A2 (en) | 1984-04-18 | 1985-01-25 | Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8604501A2 (en) |
-
1985
- 1985-01-25 ES ES540192A patent/ES8604501A2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES540192A0 (en) | 1986-02-01 |
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