ES8604501A2 - Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines - Google Patents

Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines

Info

Publication number
ES8604501A2
ES8604501A2 ES540192A ES540192A ES8604501A2 ES 8604501 A2 ES8604501 A2 ES 8604501A2 ES 540192 A ES540192 A ES 540192A ES 540192 A ES540192 A ES 540192A ES 8604501 A2 ES8604501 A2 ES 8604501A2
Authority
ES
Spain
Prior art keywords
formula
obtaining
alkyl
sulphonamidines
thio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES540192A
Other languages
Spanish (es)
Other versions
ES540192A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ferrer Internacional SA
Original Assignee
Ferrer Internacional SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferrer Internacional SA filed Critical Ferrer Internacional SA
Priority to ES540192A priority Critical patent/ES8604501A2/en
Priority to CA000477755A priority patent/CA1269382A/en
Priority to PH32140A priority patent/PH21779A/en
Priority to EP85104577A priority patent/EP0159012B1/en
Priority to DE8585104577T priority patent/DE3568041D1/en
Priority to US06/724,784 priority patent/US4728655A/en
Publication of ES540192A0 publication Critical patent/ES540192A0/en
Publication of ES8604501A2 publication Critical patent/ES8604501A2/en
Expired legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Process for obtaining sulphonamidines of general formula I". Comprises preparing a compound of formula I" where R" is 2-[[[2-[(aminoiminomethyl)amino]-4- thiazolyl]methyl]thio]ethyl and R"1 is phenyl substituted by halogen, alkoxy carbonyl, dialkylamino, nitro, alkyl sulphonyl, alkyl sulphonyl amino and alkyl thio, and their therapeutically acceptable salts, by reacting an amine of formula II" where R" has the same meaning as in I" with an excess of an orthoformate of formula III in which R2 is alkyl, thus obtaining the intermediate imidate of formula IV", where B" and R2 have the same meanings as in the previous structures, which in turn is caused to react with the sulphonamide of formula V", where R"1 has the same meaning as in I", in an alkanolic medium. Useful for inhibiting acid secretion through antagonism of H-2 histamine receptors. R"-NH-CH=N-SO2-R"1(I") R"-NH2 (II") H-C(OR2)3 (III) R"-N=CH-OR2 (IV") H2N-SO2-R"1 (V")
ES540192A 1984-04-18 1985-01-25 Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines Expired ES8604501A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
ES540192A ES8604501A2 (en) 1985-01-25 1985-01-25 Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines
CA000477755A CA1269382A (en) 1984-04-18 1985-03-28 Anti-ulceric sulfonamidines
PH32140A PH21779A (en) 1984-04-18 1985-04-15 Sulfonomidines and pharmaceutical compositions containing the same
EP85104577A EP0159012B1 (en) 1984-04-18 1985-04-16 Sulfonamidines, a process for preparing them and pharmaceutical compositions containing them
DE8585104577T DE3568041D1 (en) 1984-04-18 1985-04-16 Sulfonamidines, a process for preparing them and pharmaceutical compositions containing them
US06/724,784 US4728655A (en) 1984-04-18 1985-04-18 Sulfonamidines, process for the production thereof and pharmaceutical compositions containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES540192A ES8604501A2 (en) 1985-01-25 1985-01-25 Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines

Publications (2)

Publication Number Publication Date
ES540192A0 ES540192A0 (en) 1986-02-01
ES8604501A2 true ES8604501A2 (en) 1986-02-01

Family

ID=8488664

Family Applications (1)

Application Number Title Priority Date Filing Date
ES540192A Expired ES8604501A2 (en) 1984-04-18 1985-01-25 Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines

Country Status (1)

Country Link
ES (1) ES8604501A2 (en)

Also Published As

Publication number Publication date
ES540192A0 (en) 1986-02-01

Similar Documents

Publication Publication Date Title
EP0610958A3 (en) Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives.
DK0415456T3 (en) xanthine
ES557582A0 (en) A PROCEDURE FOR PREPARING DERIVATIVES OF (BENZOIL-4-PIPERIDINIL-1) -2-FENIL-1-ALCANOLES
SE8406141L (en) N-ACYLAMINO ACID DIAMIDE DERIVATIVES, SALTS THEREOF, PROCEDURES FOR THE PREPARATION OF THEIR AND ANTIULCER AGENTS CONTAINING THESE
ES557392A0 (en) A PROCEDURE FOR PREPARING TETRAZOLE-SUBSTITUTED-BENZENE-SULPHONAMIDES
ES8604501A2 (en) Improvements in the subject matter of patent of invention no. 532,242 relating to process for obtaining sulphonamidines
SE8008555L (en) TIOETYLAMIDDERIVAT
ES515872A0 (en) "PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF 4-PHENOXIALCARBOXYLIC ACID SUBSTITUTED WITH HATERO-CYCLIC RADICALS".
DE3162210D1 (en) A method and intermediates for preparing 3,3'-azo-bis-(6-hydroxy benzoic acid)
ES8604500A2 (en) Improvements in the subject matter of patent of invention no. 531,764 relating to process for obtaining new sulphonamidines
ES8604503A2 (en) Improvements in the subject matter of patent of invention no. 532,242 relating to Process for obtaining sulphonamidines
PL145084B1 (en) Method of obtaining novel derivatives of iminotriazolidine
PT83064A (en) Process for the preparation of acid 4-oh-quinoline-carboxylic new derivatives relieved in the position 2 by a eventually converted in ether or ester dihydroxylade group
ES8601910A1 (en) New amidine derivatives of 2-substituted 4-phenilimidazole.
ATE60779T1 (en) N-GLYCOLYLNEURAMINIC ACID DERIVATIVE.
ES532098A0 (en) A PROCEDURE FOR PREPARING SUBSTITUTED DERIVATIVES IN POSITION 1 OF AZETIDIN-3-OL
DE3675111D1 (en) NEW TETRAOXY CONNECTIONS.
ES8604502A2 (en) Improvements in the subject matter of patent of invention no. 531,764 relating to "Process for obtaining new sulphonamidines"
IE830293L (en) Pyrimidones and intermediates.
DK446183D0 (en) PROCEDURE FOR PREPARING 6H-BIBENZ (B, E) (1,4) OXATHIEPINES
ES2061494T3 (en) PROCESS FOR THE PREPARATION OF CEPHALOSPORIN DERIVATIVES.
DK385085D0 (en) CRYSTALLIC SODIUM SALT OF D-6- (ALFA - ((2-OXO-3-FURFURYLIDEN-AMINOIMIDAZOLIDIN-1-YL) CARBONYLAMINO) -THIENYL-2-ACETAMIDO) -PENICILLANIC ACID, EXCEPT PREPARED TO EXCEED
AR240920A2 (en) Quinoline derivatives, their preparation and therapeutic compositions containing the same
JPS6426564A (en) Hydantoin derivative
SE8207477D0 (en) A PROCESS FOR THE PREPARATION OF HETEROCYCLIC ACETIC ACID DERIVATIVES