ES8602581A1 - Un procedimiento para la preparacion de 2-cloro-3-trifluorme-tilbenzaldehido - Google Patents

Un procedimiento para la preparacion de 2-cloro-3-trifluorme-tilbenzaldehido

Info

Publication number
ES8602581A1
ES8602581A1 ES537782A ES537782A ES8602581A1 ES 8602581 A1 ES8602581 A1 ES 8602581A1 ES 537782 A ES537782 A ES 537782A ES 537782 A ES537782 A ES 537782A ES 8602581 A1 ES8602581 A1 ES 8602581A1
Authority
ES
Spain
Prior art keywords
pref
reacted
preparation
benzaldehyde derivative
lithium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES537782A
Other languages
English (en)
Other versions
ES537782A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp
Original Assignee
Pfizer Corp Belgium
Pfizer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp filed Critical Pfizer Corp Belgium
Publication of ES8602581A1 publication Critical patent/ES8602581A1/es
Publication of ES537782A0 publication Critical patent/ES537782A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/55—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/80—Separation; Purification; Stabilisation; Use of additives by liquid-liquid treatment

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE 2-CLORO-3-TRIFLUORMETILBENZALDEHIDO. COMPRENDE LAS SIGUIENTES ETAPAS: PRIMERA, SE HACE REACCIONAR 2-CLORO-1-TRIFLUORMETILBENCENO CON UN (ALQUIL C1-4)-LITIO O FENIL-LITIO, EFECTUANDOSE DICHA REACCION EN UN DISOLVENTE ORGANICO A -60 GRADOS; SEGUNDA, SE HACE REACCIONAR EL PRODUCTO OBTENIDO EN LA ETAPA ANTERIOR CON N,N-DIMETIL-FORMAMIDA A -60 GRADOS; Y POR ULTIMO, EL PRODUCTO OBTENIDO EN LA SEGUNDA ETAPA SE HACE REACCIONAR CON AGUA. DE APLICACION COMO UN COMPUESTO INTERMEDIO UTIL EN LA PREPARACION DE CIERTOS PRODUCTOS FARMACEUTICOS.
ES537782A 1983-11-22 1984-11-20 Un procedimiento para la preparacion de 2-cloro-3-trifluorme-tilbenzaldehido Granted ES537782A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB838331120A GB8331120D0 (en) 1983-11-22 1983-11-22 Benzaldehyde derivatives

Publications (2)

Publication Number Publication Date
ES8602581A1 true ES8602581A1 (es) 1985-12-01
ES537782A0 ES537782A0 (es) 1985-12-01

Family

ID=10552149

Family Applications (1)

Application Number Title Priority Date Filing Date
ES537782A Granted ES537782A0 (es) 1983-11-22 1984-11-20 Un procedimiento para la preparacion de 2-cloro-3-trifluorme-tilbenzaldehido

Country Status (11)

Country Link
EP (1) EP0145334A3 (es)
JP (1) JPS60123438A (es)
KR (1) KR870001315B1 (es)
DK (1) DK552284A (es)
ES (1) ES537782A0 (es)
FI (1) FI844572L (es)
GB (1) GB8331120D0 (es)
GR (1) GR80985B (es)
HU (1) HUT37113A (es)
IL (1) IL73566A0 (es)
PL (1) PL250463A1 (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0125803A3 (en) * 1983-04-27 1987-01-21 FISONS plc Pharmaceutically active dihydropyridines
DE3915495A1 (de) * 1989-05-12 1990-11-15 Bayer Ag Kernfluorierte trifluormethylbenzaldehyde
GB9201275D0 (en) * 1992-01-21 1992-03-11 Norsk Hydro As New compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2180772A (en) * 1935-10-25 1939-11-21 Gen Aniline Works Inc Trifluoromethyl benzaldehydes
GB1080167A (en) * 1963-06-14 1967-08-23 Smith Kline French Lab Improvements in or relating to the production of halogenated benzene derivatives
PL140069B1 (en) * 1982-12-21 1987-03-31 Pfizer Method of obtaining new derivatives of dihydropiridine

Also Published As

Publication number Publication date
GR80985B (en) 1985-03-19
KR870001315B1 (ko) 1987-07-13
FI844572L (fi) 1985-05-23
JPS60123438A (ja) 1985-07-02
PL250463A1 (en) 1985-06-18
DK552284A (da) 1985-05-23
DK552284D0 (da) 1984-11-21
EP0145334A3 (en) 1985-07-10
EP0145334A2 (en) 1985-06-19
FI844572A0 (fi) 1984-11-21
KR850004090A (ko) 1985-07-01
HUT37113A (en) 1985-11-28
ES537782A0 (es) 1985-12-01
GB8331120D0 (en) 1983-12-29
IL73566A0 (en) 1985-02-28

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