ES8601930A1 - Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol - Google Patents

Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol

Info

Publication number
ES8601930A1
ES8601930A1 ES528267A ES528267A ES8601930A1 ES 8601930 A1 ES8601930 A1 ES 8601930A1 ES 528267 A ES528267 A ES 528267A ES 528267 A ES528267 A ES 528267A ES 8601930 A1 ES8601930 A1 ES 8601930A1
Authority
ES
Spain
Prior art keywords
lower alkyl
substituted
lower alkylene
thia
aza
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES528267A
Other languages
English (en)
Other versions
ES528267A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8601930A1 publication Critical patent/ES8601930A1/es
Publication of ES528267A0 publication Critical patent/ES528267A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C247/00—Compounds containing azido groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE NUEVOS COMPUESTOS DE ARALQUITRIAZOL.CONSISTE EN HACER REACCIONAR UNA AZIDA DE FORMULA (II) CON UN COMPUESTO DE FORMULA (III) EN UN DISOLVENTE INERTE, COMO HIDROCARBUROS AROMATICOS O ARALIFATICOS TIPO BENCENO, TOLUENO, TETRAHIDROFURANO Y OTROS, UN AGENTE DE CONDENSACION Y, A TEMPERATURA DE EBULLICION, PARA OBTENER COMPUESTOS DE 1-FENILO-ALQUILO INFERIOR-1H-1,2,3-TRIAZOL DE FORMULA (I). SIENDO: ALK, ALQUILIDENO INFERIOR; R1, H, ALQUILO INFERIOR, ALCOXI INFERIOR, Y OTROS; R2 GRUPO CARBAMILO INSUSTITUIDO O SUSTITUIDO POR UN ACILO ALQUILO INFERIOR; R2 GRUPO CARBAMILO INSUSTITUIDO O SUSTITUIDO POR UN ACILO ALQUILO INFERIOR; PH, FENILO, SUSTITUIDO POR ALQUILO INFERIOR, HAL, Y/O TRIFLUORMETILO; Y, GRUPO AMINO DISUSTITUIDO; T2 E Y3 JUNTOS, ENLACE ADICIONAL, OXA O TIA-ALQUENILO; Y3, H.SE UTILIZAN COMO ANTICONVULSIVOS.
ES528267A 1982-12-23 1983-12-21 Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol Granted ES528267A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH752682 1982-12-23

Publications (2)

Publication Number Publication Date
ES8601930A1 true ES8601930A1 (es) 1985-11-16
ES528267A0 ES528267A0 (es) 1985-11-16

Family

ID=4326531

Family Applications (3)

Application Number Title Priority Date Filing Date
ES528267A Granted ES528267A0 (es) 1982-12-23 1983-12-21 Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol
ES543623A Expired ES8608495A1 (es) 1982-12-23 1985-05-29 Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol
ES543624A Expired ES8608496A1 (es) 1982-12-23 1985-05-29 Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES543623A Expired ES8608495A1 (es) 1982-12-23 1985-05-29 Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol
ES543624A Expired ES8608496A1 (es) 1982-12-23 1985-05-29 Procedimiento para la obtencion de nuevos compuestos de aralquiltriazol

Country Status (14)

Country Link
EP (1) EP0114347A3 (es)
JP (1) JPS59118775A (es)
AU (1) AU566730B2 (es)
DD (1) DD216456A5 (es)
DK (1) DK591983A (es)
ES (3) ES528267A0 (es)
FI (1) FI834666A (es)
GR (1) GR79452B (es)
HU (1) HU191388B (es)
IL (1) IL70508A (es)
NO (1) NO834770L (es)
NZ (1) NZ206696A (es)
PT (1) PT77867B (es)
ZA (1) ZA839478B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0151528B1 (en) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(amino or substituted amino)-1,2,3-triazoles
PH22568A (en) * 1985-04-18 1988-10-17 Ciba Geigy Ag Fluorinated benzyl triazoles and pharmaceutical compositions containing the same
US5880129A (en) * 1989-05-19 1999-03-09 The United States Of America As Represented By The Department Of Health And Human Services Methods of inhibiting invasion and metastasis of malignant solid tumors
US5359078A (en) * 1989-05-19 1994-10-25 The United States Of America As Represented By The Department Of Health And Human Services Signal transduction inhibitor compounds
US5498620A (en) * 1989-05-19 1996-03-12 The United States Of America As Represented By The Department Of Health And Human Services Signal transduction inhibitor 1,2,3-triazolo compounds
WO1997040025A1 (en) * 1996-04-19 1997-10-30 Novo Nordisk A/S Solid phase and combinatorial synthesis of substituted 1,2,3-triazoles and of arrays of substituted 1,2,3-triazoles
TW526195B (en) 1997-06-10 2003-04-01 Novartis Ag Crystal modifications of 1-(2,6-difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide and their use
GB0507298D0 (en) 2005-04-11 2005-05-18 Novartis Ag Organic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL50699A0 (en) * 1975-10-28 1976-12-31 Ici America Inc Triazole derivatives
CH632291A5 (de) * 1978-01-10 1982-09-30 Sandoz Ag Organische azoverbindungen.
CH639376A5 (en) * 1979-02-14 1983-11-15 Sandoz Ag Process for preparing disperse dyes of the triazolylazo class

Also Published As

Publication number Publication date
PT77867B (en) 1986-05-08
EP0114347A2 (de) 1984-08-01
AU2280783A (en) 1984-06-28
ES543624A0 (es) 1986-06-16
ZA839478B (en) 1984-08-29
DK591983D0 (da) 1983-12-22
DK591983A (da) 1984-06-24
PT77867A (en) 1984-01-01
NZ206696A (en) 1986-02-21
FI834666A (fi) 1984-06-24
AU566730B2 (en) 1987-10-29
FI834666A0 (fi) 1983-12-19
ES528267A0 (es) 1985-11-16
NO834770L (no) 1984-06-25
ES8608495A1 (es) 1986-06-16
ES543623A0 (es) 1986-06-16
HU191388B (en) 1987-02-27
GR79452B (es) 1984-10-30
EP0114347A3 (de) 1986-01-29
DD216456A5 (de) 1984-12-12
IL70508A (en) 1988-03-31
IL70508A0 (en) 1984-03-30
ES8608496A1 (es) 1986-06-16
JPS59118775A (ja) 1984-07-09

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