ES8504783A1 - Procedimiento para preparar imidazolamidas - Google Patents

Procedimiento para preparar imidazolamidas

Info

Publication number
ES8504783A1
ES8504783A1 ES530037A ES530037A ES8504783A1 ES 8504783 A1 ES8504783 A1 ES 8504783A1 ES 530037 A ES530037 A ES 530037A ES 530037 A ES530037 A ES 530037A ES 8504783 A1 ES8504783 A1 ES 8504783A1
Authority
ES
Spain
Prior art keywords
imidazol
omega
amides
alkyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530037A
Other languages
English (en)
Other versions
ES530037A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES8504783A1 publication Critical patent/ES8504783A1/es
Publication of ES530037A0 publication Critical patent/ES530037A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D411/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D411/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D411/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen and sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR IMIDAZOLAMIDAS.COMPRENDE: A) CONDENSAR UN ACIDO DE FORMULA (II), CON 1,1-CARBONILDIIMIDAZOL, PARA OBTENER UN COMPUESTO DE FORMULA (III); Y B) HACER REACCIONAR A (III) CON UNA DIAMINA DE FORMULA (IV) EN UN DISOLVENTE INERTE Y A TEMPERATURA DE REFLUJO, PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES DE ADICION DE ACIDO FARMACOLOGICAMENTE ACEPTABLES, SIENDO HET UNA MITAD HETEROCICLICA DE FORMULA (V), (VI) U OTROS; Q UNA MITAD DIVALENTE DE FORMULA (-CMH2M), (-CHFCH-) U OTROS; A UNA MITAD DIVALENTE DE FORMULA (-CNH2N) O (-CH2-CHFCH-CH2); R1, R2 Y R3, ALQUILO DE C 1 A 3 Y OTROS; R4, H, HALOGENO Y OTROS; Y (-O-) O (-S-); N DE 2 A 8; Y M, 0, 1, 2 O 3.
ES530037A 1983-04-06 1984-02-24 Procedimiento para preparar imidazolamidas Granted ES530037A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US48238883A 1983-04-06 1983-04-06

Publications (2)

Publication Number Publication Date
ES8504783A1 true ES8504783A1 (es) 1985-05-01
ES530037A0 ES530037A0 (es) 1985-05-01

Family

ID=23915864

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530037A Granted ES530037A0 (es) 1983-04-06 1984-02-24 Procedimiento para preparar imidazolamidas

Country Status (11)

Country Link
EP (1) EP0127727A3 (es)
JP (1) JPS59190991A (es)
KR (1) KR840008358A (es)
AU (1) AU2461584A (es)
DD (1) DD216927A5 (es)
DE (1) DE3406414A1 (es)
DK (1) DK119484A (es)
ES (1) ES530037A0 (es)
GR (1) GR79911B (es)
HU (1) HUT34021A (es)
ZA (1) ZA84949B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4696930A (en) * 1985-04-12 1987-09-29 Hoffmann-La Roche Inc. N-(heteroarylalkyl)acylanilide derivatives as antiarrhythmic agents
IL87019A (en) * 1987-07-10 1993-07-08 Hoffmann La Roche Substituted alkene carboxamides and derivatives, their manufacture and pharmaceutical compositions containing them
US5100909A (en) * 1988-07-25 1992-03-31 The Upjohn Company Acetylenic imidazoles having central nervous system activity
AU620894B2 (en) * 1988-07-25 1992-02-27 Upjohn Company, The Acetylenic imidazoles having central nervous system activity
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
EP1487796A4 (en) * 2002-03-28 2005-11-16 Neurogen Corp SUBSTITUTED BIARYLAMIDES AS MODULATORS OF THE C5A RECEPTOR
US6858637B2 (en) 2002-03-28 2005-02-22 Neurogen Corporation Substituted biaryl amides as C5a receptor modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3646057A (en) * 1969-04-06 1972-02-29 Hoffmann La Roche 2-nitroimidazoles
DE2854598A1 (de) * 1978-12-18 1980-07-03 Basf Ag N-substituierte carbonsaeureanilide, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide

Also Published As

Publication number Publication date
KR840008358A (ko) 1984-12-14
DE3406414A1 (de) 1984-10-11
DK119484A (da) 1984-10-07
JPS59190991A (ja) 1984-10-29
AU2461584A (en) 1984-10-11
DK119484D0 (da) 1984-02-28
EP0127727A2 (en) 1984-12-12
ES530037A0 (es) 1985-05-01
HUT34021A (en) 1985-01-28
ZA84949B (en) 1984-09-26
GR79911B (es) 1984-10-31
EP0127727A3 (en) 1986-08-20
DD216927A5 (de) 1985-01-02

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