ES8502677A1 - Hydroxylated Diphenylazomethines, their Preparation and Pharmaceutical Compositions Containing Them - Google Patents

Hydroxylated Diphenylazomethines, their Preparation and Pharmaceutical Compositions Containing Them

Info

Publication number
ES8502677A1
ES8502677A1 ES531605A ES531605A ES8502677A1 ES 8502677 A1 ES8502677 A1 ES 8502677A1 ES 531605 A ES531605 A ES 531605A ES 531605 A ES531605 A ES 531605A ES 8502677 A1 ES8502677 A1 ES 8502677A1
Authority
ES
Spain
Prior art keywords
hydroxylated
alkyl
diphenylazomethines
preparation
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES531605A
Other languages
Spanish (es)
Other versions
ES531605A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of ES8502677A1 publication Critical patent/ES8502677A1/en
Publication of ES531605A0 publication Critical patent/ES531605A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Hydroxylated diphenylazomethine of the formula (I> < IMAGE > in which n is an integer from 1 to 4, X1, X2 and X3, which may be the same or different, each represent a hydrogen atom, a halogen atom, -OCH3 or a straight-chain or branched C1-4-alkyl group, R represents NH2, -OH or -OM/p (wherein M represents an alkali metal or alkaline earth metal of valency p) and Z represents -COOH, -COOalkyl, -CONH2, -CONHalkyl, -CON(alkyl)2, -CH2OH, -CH2Oalkyl, -Oalkyl, -NO2,- -NH2, -NHalkyl or -N(alkyl)2, each alkyl moiety having 1 to 4 carbon atoms act on the central nervous system and find use as antidepressants and anticonvulsants.
ES531605A 1983-04-14 1984-04-13 PROCEDURE FOR PREPARING HYDROXYLATED DIPHENYLAZOMETINS Granted ES531605A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8306082A FR2544309B1 (en) 1983-04-14 1983-04-14 HYDROXYLATED DIPHENYLAZOMETHINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
ES8502677A1 true ES8502677A1 (en) 1985-01-16
ES531605A0 ES531605A0 (en) 1985-01-16

Family

ID=9287836

Family Applications (1)

Application Number Title Priority Date Filing Date
ES531605A Granted ES531605A0 (en) 1983-04-14 1984-04-13 PROCEDURE FOR PREPARING HYDROXYLATED DIPHENYLAZOMETINS

Country Status (20)

Country Link
JP (1) JPS59199665A (en)
AU (1) AU2682584A (en)
BE (1) BE899423A (en)
DE (1) DE3414051A1 (en)
DK (1) DK191684A (en)
ES (1) ES531605A0 (en)
FI (1) FI841484A (en)
FR (1) FR2544309B1 (en)
GB (1) GB2138000A (en)
GR (1) GR79857B (en)
HU (1) HUT34153A (en)
IL (1) IL71540A0 (en)
IT (1) IT1176042B (en)
LU (1) LU85311A1 (en)
NL (1) NL8401189A (en)
NO (1) NO841486L (en)
NZ (1) NZ207840A (en)
PT (1) PT78429B (en)
SE (1) SE8402082L (en)
ZA (1) ZA842798B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1212000B (en) * 1987-12-24 1989-11-08 Sigma Tau Ind Farmaceuti PHENYLBENZYLIDEN-DERIVATIVES OF ACID 3) AMINOPROPANSULPHONIC WITH ANTI-CONVULSIVE ACTIVITY AND THEIR PHARMACEUTICAL COMPOSITIONS FOR THE THERAPEUTIC TREATMENT OF EPILEPSY
FR2788691B1 (en) 1999-01-21 2002-06-14 Oreal COMPOSITIONS FOR OXIDATION DYEING OF KERATINIC FIBERS COMPRISING A CATIONIC COUPLER, NOVEL CATIONIC COUPLERS, THEIR USE FOR OXIDATION DYEING, AND DYEING METHODS
FR2788768B1 (en) 1999-01-21 2001-02-16 Oreal NEW CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS COMPRISING THEM, AND DYEING METHODS

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2319338A1 (en) * 1975-08-01 1977-02-25 Synthelabo NEW A-PHENYL BENZYLIDENIC DERIVATIVES OF AMINO ACIDS, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM
FR2516509B1 (en) * 1981-11-18 1985-07-26 Synthelabo BENZYLIDENIC DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2430936A1 (en) * 1978-07-13 1980-02-08 Synthelabo Alpha-phenyl 2-hydroxy-benzylidene amino-alkanoic acid derivs. - and novel di:phenyl-ketone intermediates, useful as anticonvulsants for treating epilepsy

Also Published As

Publication number Publication date
ZA842798B (en) 1984-11-28
PT78429B (en) 1986-08-22
DK191684D0 (en) 1984-04-13
DE3414051A1 (en) 1984-10-18
IT1176042B (en) 1987-08-12
SE8402082D0 (en) 1984-04-13
JPS59199665A (en) 1984-11-12
IL71540A0 (en) 1984-07-31
FR2544309B1 (en) 1986-01-10
FI841484A (en) 1984-10-15
AU2682584A (en) 1984-10-18
HUT34153A (en) 1985-02-28
DK191684A (en) 1984-10-15
PT78429A (en) 1984-05-01
BE899423A (en) 1984-10-15
ES531605A0 (en) 1985-01-16
GR79857B (en) 1984-10-31
NL8401189A (en) 1984-11-01
FI841484A0 (en) 1984-04-13
NO841486L (en) 1984-10-15
LU85311A1 (en) 1985-11-27
SE8402082L (en) 1984-10-15
FR2544309A1 (en) 1984-10-19
NZ207840A (en) 1986-02-21
IT8420528A0 (en) 1984-04-13
GB2138000A (en) 1984-10-17

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