ES8500620A1 - E-homo-eburnane derivatives - Google Patents

E-homo-eburnane derivatives

Info

Publication number
ES8500620A1
ES8500620A1 ES523696A ES523696A ES8500620A1 ES 8500620 A1 ES8500620 A1 ES 8500620A1 ES 523696 A ES523696 A ES 523696A ES 523696 A ES523696 A ES 523696A ES 8500620 A1 ES8500620 A1 ES 8500620A1
Authority
ES
Spain
Prior art keywords
homo
series
eburnane derivatives
eburnane
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523696A
Other languages
Spanish (es)
Other versions
ES523696A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES8500620A1 publication Critical patent/ES8500620A1/en
Publication of ES523696A0 publication Critical patent/ES523696A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

E-homo-eburnane derivatives of formula ÄIÜ, < IMAGE > wherein R<1> and R<2> each independently represents an alkyl group having 1 to 6 carbon atoms, and acid addition salts thereof are pharmaceutically active. Certain representatives, in particular from the cis-series, show antidepressant activity, while others, especially the compounds of the trans-series, are antihypoxial agents.
ES523696A 1982-06-30 1983-06-29 PROCEDURE FOR THE PREPARATION OF RACEMIC OR OPTICALLY ACTIVE E-HOMO-EBURNAN DERIVATIVES AND THEIR ACIDIC ADDITIONAL SALTS. Granted ES523696A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU822130A HU190399B (en) 1982-06-30 1982-06-30 Process for the production of e-homo-eburnane-derivatives

Publications (2)

Publication Number Publication Date
ES8500620A1 true ES8500620A1 (en) 1984-11-01
ES523696A0 ES523696A0 (en) 1984-11-01

Family

ID=10957916

Family Applications (1)

Application Number Title Priority Date Filing Date
ES523696A Granted ES523696A0 (en) 1982-06-30 1983-06-29 PROCEDURE FOR THE PREPARATION OF RACEMIC OR OPTICALLY ACTIVE E-HOMO-EBURNAN DERIVATIVES AND THEIR ACIDIC ADDITIONAL SALTS.

Country Status (17)

Country Link
JP (1) JPS5913782A (en)
AU (1) AU553966B2 (en)
BE (1) BE897147A (en)
CA (1) CA1192189A (en)
CH (1) CH660735A5 (en)
DE (1) DE3323584A1 (en)
DK (1) DK300383A (en)
ES (1) ES523696A0 (en)
FR (1) FR2529554B1 (en)
GB (1) GB2122994B (en)
GR (1) GR78602B (en)
HU (1) HU190399B (en)
IL (1) IL69106A (en)
NL (1) NL8302297A (en)
NZ (1) NZ204756A (en)
PT (1) PT76950B (en)
SE (1) SE8303718L (en)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU181496B (en) * 1979-08-13 1983-07-28 Richter Gedeon Vegyeszet Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes

Also Published As

Publication number Publication date
GB2122994A (en) 1984-01-25
GR78602B (en) 1984-09-27
IL69106A0 (en) 1983-10-31
DK300383D0 (en) 1983-06-29
AU553966B2 (en) 1986-07-31
GB2122994B (en) 1985-08-29
HU190399B (en) 1986-08-28
PT76950B (en) 1986-01-24
BE897147A (en) 1983-12-28
FR2529554A1 (en) 1984-01-06
AU1639583A (en) 1984-01-05
FR2529554B1 (en) 1985-08-09
NL8302297A (en) 1984-01-16
CA1192189A (en) 1985-08-20
SE8303718L (en) 1983-12-31
JPS5913782A (en) 1984-01-24
DK300383A (en) 1983-12-31
IL69106A (en) 1986-02-28
GB8317611D0 (en) 1983-08-03
DE3323584A1 (en) 1984-02-09
CH660735A5 (en) 1987-06-15
ES523696A0 (en) 1984-11-01
PT76950A (en) 1983-07-01
NZ204756A (en) 1985-09-13
SE8303718D0 (en) 1983-06-29

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