ES8405441A1 - Un procedimiento para la preparacion de glutation. - Google Patents

Un procedimiento para la preparacion de glutation.

Info

Publication number
ES8405441A1
ES8405441A1 ES521152A ES521152A ES8405441A1 ES 8405441 A1 ES8405441 A1 ES 8405441A1 ES 521152 A ES521152 A ES 521152A ES 521152 A ES521152 A ES 521152A ES 8405441 A1 ES8405441 A1 ES 8405441A1
Authority
ES
Spain
Prior art keywords
microorganisms
glutation
preparation
glutathione
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521152A
Other languages
English (en)
Other versions
ES521152A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES8405441A1 publication Critical patent/ES8405441A1/es
Publication of ES521152A0 publication Critical patent/ES521152A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/848—Escherichia
    • Y10S435/849—Escherichia coli

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE GLUTATION.COMPRENDE: A) CULTIVAR EN UN MEDIO DE CULTIVO UNA NUEVA CEPA MUTANTE DEL GENERO ESCHERICHIA, ACTIVA SOBRE UN SISTEMA ENZIMATICO Y-GLUTAMIL-L-CISTEINA-SINTETASA Y GLUTATION SINTETASA, DERIVADA DE UNA CEPA MADRE IGUALMENTE ACTIVA Y CAPAZ DE DESPRENDER EL ENZIMA DE LA INHIBICION POR GLUTATION, INTEGRADA CON UN ADN CROMOSOMICO DE UNA CEPA DEL GENERO ESCHERICHIA COLI QUE IMPLICA LA INFORMACION GENETICA SOBRE EL ENZIMA; B) COLOCAR EL SISTEMA ENZIMATICO ASI OBTENIDO EN CONTACTO CON UNA DISOLUCION DE SUSTRATO DE ACIDO L-GLUTANICO, L-CISTEINAY GLICINA, PARA EFECTUAR UNA REACCION ENZIMATICA PARA FORMACION DE GLUTATION, RECUPERANDO ESTE DE LA DISOLUCION DE REACCION.TIENE APLICACIONES COMO MEDICAMENTO PARA TRATAR LAS ENFERMEDADES DEL HIGADO, COMO ANTIDOTO Y COMO REACTIVO BIOQUIMICO.
ES521152A 1981-07-30 1983-03-30 Un procedimiento para la preparacion de glutation. Granted ES521152A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56120546A JPS5820188A (ja) 1981-07-30 1981-07-30 新規微生物及びそれを用いるグルタチオンの製造法

Publications (2)

Publication Number Publication Date
ES8405441A1 true ES8405441A1 (es) 1984-06-01
ES521152A0 ES521152A0 (es) 1984-06-01

Family

ID=14788972

Family Applications (2)

Application Number Title Priority Date Filing Date
ES514572A Expired ES8308362A1 (es) 1981-07-30 1982-07-30 "un procedimiento para la preparacion de glutation".
ES521152A Granted ES521152A0 (es) 1981-07-30 1983-03-30 Un procedimiento para la preparacion de glutation.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES514572A Expired ES8308362A1 (es) 1981-07-30 1982-07-30 "un procedimiento para la preparacion de glutation".

Country Status (6)

Country Link
US (1) US4598046A (es)
EP (1) EP0071486B1 (es)
JP (1) JPS5820188A (es)
CA (1) CA1187430A (es)
DE (1) DE3279949D1 (es)
ES (2) ES8308362A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59192088A (ja) * 1982-09-29 1984-10-31 Hikari Kimura 遺伝子組換えで造成されるプラスミド
JPS60105499A (ja) * 1983-11-15 1985-06-10 Kyowa Hakko Kogyo Co Ltd グルタチオンの製造方法
US4927808A (en) * 1986-07-07 1990-05-22 Teijin Limited γ-L-glutamyl-L-cysteine ethyl ester and pharmaceutical compositions containing the same as an effective ingredient
DE3909105A1 (de) * 1989-03-20 1990-09-27 Gerd Hoermansdoerfer Waermerohr
US5510243A (en) * 1994-06-21 1996-04-23 Gelman Sciences, Inc. Multiple chromogen enzyme targeting (MCET) for use in bacterial contamination monitoring
CN105906688A (zh) * 2016-05-01 2016-08-31 江苏诚信药业有限公司 一种谷胱甘肽的提取工艺系统及工艺方法
JP7181712B2 (ja) * 2018-06-27 2022-12-01 国立大学法人大阪大学 グルタチオンの製造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4237224A (en) * 1974-11-04 1980-12-02 Board Of Trustees Of The Leland Stanford Jr. University Process for producing biologically functional molecular chimeras
JPS6041599B2 (ja) * 1979-12-07 1985-09-18 田辺製薬株式会社 グルタチオンの製法

Also Published As

Publication number Publication date
ES514572A0 (es) 1983-08-16
EP0071486B1 (en) 1989-09-20
EP0071486A3 (en) 1984-03-28
EP0071486A2 (en) 1983-02-09
ES521152A0 (es) 1984-06-01
CA1187430A (en) 1985-05-21
JPS5820188A (ja) 1983-02-05
DE3279949D1 (en) 1989-10-26
US4598046A (en) 1986-07-01
ES8308362A1 (es) 1983-08-16

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