ES8405370A1 - Un procedimiento para preparar diasteredisomeros derivados de pirrolidina - Google Patents

Un procedimiento para preparar diasteredisomeros derivados de pirrolidina

Info

Publication number
ES8405370A1
ES8405370A1 ES526077A ES526077A ES8405370A1 ES 8405370 A1 ES8405370 A1 ES 8405370A1 ES 526077 A ES526077 A ES 526077A ES 526077 A ES526077 A ES 526077A ES 8405370 A1 ES8405370 A1 ES 8405370A1
Authority
ES
Spain
Prior art keywords
toluoil
ethyl
tartrate
translation
derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES526077A
Other languages
English (en)
Other versions
ES526077A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Pharmaceutical Production AB
Astra USA Inc
Original Assignee
Astra Pharmaceutical Production AB
Astra Pharmaceutical Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Pharmaceutical Production AB, Astra Pharmaceutical Products Inc filed Critical Astra Pharmaceutical Production AB
Publication of ES8405370A1 publication Critical patent/ES8405370A1/es
Publication of ES526077A0 publication Critical patent/ES526077A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR DIASTEREDISOMEROS DERIVADOS DE 1-ETIL-2-AMINOMETILPIRROLIDINA.SE DISUELVE LA 1-ETIL-2-AMINOMETILPIRROLIDINA RACEMICA EN METANOL ACUOSO Y SE TRATA CON ACIDO (-)-DI-P-TOLUOIL-L-TARTARICO CON LO QUE CRISTALIZA (-)-DI-P-TOLUOIL-L-TARTRATO DE LEVO-1-ETIL-2-AMINOMETILPIRROLIDINA Y SE AISLA Y EL (-)-DI-P-TOLUOIL-L-TARTRATO DE DEXTRO-1-ETIL-2-AMINOMETILPIRROLIDINA PERMANECE EN LAS MADRES O SE TRATA 1-ETIL-2-AMINOMETILPIR ROLIDINA RACEMICA CON ACIDO (-)-DI-P-TOLUOIL-L-TARTARICO EN METANOL CON LO QUE CRISTALIZA (-)-DI-P-TOLUOIL-L-TARTR ATO DE DEXTRO-1-ETIL-2-AMINOMETILPIRROLIDINA Y SE AISLA DESPUES LO CUAL LA ADICIONDE AGUA A LAS AGUAS MADRES DE METANOL DA COMO RESULTADO LA CRISTALIZACION DE (-)-DI-P-TOLUOIL-L-TARTRATO DE LEVO-1-ETIL-2-AMCNOMETILPI RROLIDINA.SE USA COMO COMPUESTO INTERMEDIO EN LA FABRICACION DE PRODUCTOS FARMACEUTICOS.
ES526077A 1982-09-30 1983-09-29 Un procedimiento para preparar diasteredisomeros derivados de pirrolidina Granted ES526077A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8205568A SE447991B (sv) 1982-09-30 1982-09-30 Diastereomerer av di-p-toluoyltartrat med 1-etyl-2-aminometylpyrrolidin och forfarande for framstellning av dessa

Publications (2)

Publication Number Publication Date
ES8405370A1 true ES8405370A1 (es) 1984-06-01
ES526077A0 ES526077A0 (es) 1984-06-01

Family

ID=20348031

Family Applications (1)

Application Number Title Priority Date Filing Date
ES526077A Granted ES526077A0 (es) 1982-09-30 1983-09-29 Un procedimiento para preparar diasteredisomeros derivados de pirrolidina

Country Status (10)

Country Link
AT (1) AT377980B (es)
CA (1) CA1210014A (es)
DD (1) DD210261A5 (es)
DK (1) DK435283A (es)
ES (1) ES526077A0 (es)
FI (1) FI833512A (es)
HU (1) HU189751B (es)
NO (1) NO833439L (es)
SE (1) SE447991B (es)
SU (1) SU1240353A3 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5227526A (en) * 1992-06-16 1993-07-13 Mallinckrodt Specialty Chemicals Company Resolution of 3-dimethylamino-2-methylpropiophenone (3-DAMP)
GB0217447D0 (en) * 2002-07-29 2002-09-04 Betts John A Personal deodorant

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1528014A (fr) * 1967-04-24 1968-06-07 Ile De France Procédé de préparation des isomères optiques de la éthyl-1, aminométhyl-2-pyrrolidine

Also Published As

Publication number Publication date
FI833512A0 (fi) 1983-09-29
ATA347583A (de) 1984-10-15
SE447991B (sv) 1987-01-12
FI833512A (fi) 1984-03-31
HU189751B (en) 1986-07-28
SE8205568L (sv) 1984-03-31
AT377980B (de) 1985-05-28
SU1240353A3 (ru) 1986-06-23
DK435283D0 (da) 1983-09-23
SE8205568D0 (sv) 1982-09-30
NO833439L (no) 1984-04-02
DD210261A5 (de) 1984-06-06
ES526077A0 (es) 1984-06-01
CA1210014A (en) 1986-08-19
DK435283A (da) 1984-03-31

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