ES8403457A1 - Procedimiento para la obtencion de un compuesto derivado de la 2-quinolinona. - Google Patents

Procedimiento para la obtencion de un compuesto derivado de la 2-quinolinona.

Info

Publication number
ES8403457A1
ES8403457A1 ES519384A ES519384A ES8403457A1 ES 8403457 A1 ES8403457 A1 ES 8403457A1 ES 519384 A ES519384 A ES 519384A ES 519384 A ES519384 A ES 519384A ES 8403457 A1 ES8403457 A1 ES 8403457A1
Authority
ES
Spain
Prior art keywords
bronchodilation
prodn
agent
acid
ch3ch2ch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES519384A
Other languages
English (en)
Other versions
ES519384A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
Original Assignee
Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sociedad Espanola de Especialidades Farmaco Terapeuticas SA filed Critical Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
Priority to ES519384A priority Critical patent/ES8403457A1/es
Publication of ES519384A0 publication Critical patent/ES519384A0/es
Publication of ES8403457A1 publication Critical patent/ES8403457A1/es
Expired legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE 8-HIDROXI-5-1-HIDROXI- 2-(1-METILETIL) AMINO BUTIL-2-(1H)-QUINOLINONA.CONSISTE EN LA REACCION DE 8-HIDROXI-2-(1H)-QUINOLINONA CON UN HALURO DE UN ACIDO A-HALOBUTIRICO, DE FORMULA (I), EN LA QUE X1 Y X2 PUEDEN SER CLORO O BROMO, EN PRESENCIA DE UN ACIDO DE LEWIS, TAL COMO EL TRICORURO DE ALUMINIO; SEGUIDA DEL TRATAMIENTO CON ISOPROPILAMINA; Y, FINALMENTE, REDUCCION DEL PRODUCTO FORMADO CON UN HIDRURO METALICO COMPLEJO, TAL COMO BOROHIDRURO SODICO.ESTE COMPUESTO TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD BRONCODILATADORA.
ES519384A 1983-01-28 1983-01-28 Procedimiento para la obtencion de un compuesto derivado de la 2-quinolinona. Expired ES8403457A1 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES519384A ES8403457A1 (es) 1983-01-28 1983-01-28 Procedimiento para la obtencion de un compuesto derivado de la 2-quinolinona.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES519384A ES8403457A1 (es) 1983-01-28 1983-01-28 Procedimiento para la obtencion de un compuesto derivado de la 2-quinolinona.

Publications (2)

Publication Number Publication Date
ES519384A0 ES519384A0 (es) 1984-03-16
ES8403457A1 true ES8403457A1 (es) 1984-03-16

Family

ID=8485267

Family Applications (1)

Application Number Title Priority Date Filing Date
ES519384A Expired ES8403457A1 (es) 1983-01-28 1983-01-28 Procedimiento para la obtencion de un compuesto derivado de la 2-quinolinona.

Country Status (1)

Country Link
ES (1) ES8403457A1 (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006522055A (ja) * 2003-04-02 2006-09-28 ノバルティス アクチエンゲゼルシャフト ５−（ハロアセチル）−８−（置換オキシ）−（１ｈ）−キノリン−２−オン類の製造法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006522055A (ja) * 2003-04-02 2006-09-28 ノバルティス アクチエンゲゼルシャフト ５−（ハロアセチル）−８−（置換オキシ）−（１ｈ）−キノリン−２−オン類の製造法
JP4726778B2 (ja) * 2003-04-02 2011-07-20 ノバルティス アーゲー ５−（ハロアセチル）−８−（置換オキシ）−（１ｈ）−キノリン−２−オン類の製造法

Also Published As

Publication number Publication date
ES519384A0 (es) 1984-03-16

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