ES8402820A1 - 4-difenilmetil-1-((oxoalquil)imino)metil-piperidinas y sus derivados. - Google Patents

4-difenilmetil-1-((oxoalquil)imino)metil-piperidinas y sus derivados.

Info

Publication number
ES8402820A1
ES8402820A1 ES518881A ES518881A ES8402820A1 ES 8402820 A1 ES8402820 A1 ES 8402820A1 ES 518881 A ES518881 A ES 518881A ES 518881 A ES518881 A ES 518881A ES 8402820 A1 ES8402820 A1 ES 8402820A1
Authority
ES
Spain
Prior art keywords
imino
derivatives
oxoalkyl
diphenylmethyl
piperidines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518881A
Other languages
English (en)
Other versions
ES518881A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
McNeilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeilab Inc filed Critical McNeilab Inc
Publication of ES8402820A1 publication Critical patent/ES8402820A1/es
Publication of ES518881A0 publication Critical patent/ES518881A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C07D209/49—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide and having in the molecule an acyl radical containing a saturated three-membered ring, e.g. chrysanthemumic acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE 4-DIFENILMETIL-1-(OXOALQUIL)IMINOMETIL-PIPERIDINAS Y SUS DERIVADOS, DE FORMULA GENERAL (I).CONSISTE EN HACER REACCIONAR UNA PIPERIDINA, DE FORMULA GENERAL (II), CON UN AGENTE ACTIVADOR Y EN HACER REACCIONAR LA PIPERIDINA ACTIVADA CON UNA AMINA DE FORMULA: H2N(CH2)NA(CH2)MCH3, EN LA QUE A ES C(OR1)2, PARA OBTENER UNA AMIDINA DE FORMULA (I).DE APLICACION COMO INHIBIDORES DE LA SECRECION DEL ACIDO GASTRICO.
ES518881A 1982-02-02 1983-01-11 4-difenilmetil-1-((oxoalquil)imino)metil-piperidinas y sus derivados. Granted ES518881A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/345,128 US4370335A (en) 1982-02-02 1982-02-02 Antisecretory 4-diphenylmethyl-1-[(oxoalkyl)imino]methyl-piperidines and their derivatives

Publications (2)

Publication Number Publication Date
ES8402820A1 true ES8402820A1 (es) 1984-03-01
ES518881A0 ES518881A0 (es) 1984-03-01

Family

ID=23353650

Family Applications (1)

Application Number Title Priority Date Filing Date
ES518881A Granted ES518881A0 (es) 1982-02-02 1983-01-11 4-difenilmetil-1-((oxoalquil)imino)metil-piperidinas y sus derivados.

Country Status (14)

Country Link
US (1) US4370335A (es)
EP (1) EP0087853B1 (es)
JP (1) JPS58146564A (es)
KR (1) KR840003251A (es)
AT (1) ATE19512T1 (es)
AU (1) AU552804B2 (es)
DE (1) DE3363208D1 (es)
DK (1) DK7983A (es)
ES (1) ES518881A0 (es)
FI (1) FI830105L (es)
IL (1) IL67674A0 (es)
NO (1) NO830042L (es)
PH (1) PH17775A (es)
ZA (1) ZA83109B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4528293A (en) * 1983-10-11 1985-07-09 Mcneilab, Inc. Heteroaromatic derivatives of iminomethyl piperidines and use to inhibit gastric acid secretion
US4594351A (en) * 1983-10-11 1986-06-10 Mcneilab, Inc. Furan or thiophene derivatives of iminomethyl piperidines and use to inhibit gastric secretion
JP5463055B2 (ja) * 2009-02-27 2014-04-09 公益財団法人相模中央化学研究所 フタルイミド誘導体及びそれらの製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE794596A (fr) * 1972-01-28 1973-05-16 Richardson Merrell Inc Piperidinoalcanone-oximes substituees et leur procede de preparation
US3946022A (en) * 1974-03-04 1976-03-23 Richardson-Merrell Inc. Piperidine derivatives
FR2314179A1 (fr) * 1975-06-12 1977-01-07 Ile De France Nouvelles enamines et leur procede de preparation
US4251655A (en) * 1978-03-29 1981-02-17 Mcneilab, Inc. Substituted N-iminomethylpiperidines

Also Published As

Publication number Publication date
DK7983A (da) 1983-08-03
EP0087853A2 (en) 1983-09-07
NO830042L (no) 1983-08-03
IL67674A0 (en) 1983-05-15
JPS58146564A (ja) 1983-09-01
ZA83109B (en) 1984-08-29
ATE19512T1 (de) 1986-05-15
AU552804B2 (en) 1986-06-19
DE3363208D1 (en) 1986-06-05
KR840003251A (ko) 1984-08-20
FI830105L (fi) 1983-08-03
US4370335A (en) 1983-01-25
AU1086283A (en) 1983-08-11
DK7983D0 (da) 1983-01-10
ES518881A0 (es) 1984-03-01
EP0087853A3 (en) 1983-10-05
FI830105A0 (fi) 1983-01-12
EP0087853B1 (en) 1986-04-30
PH17775A (en) 1984-12-11

Similar Documents

Publication Publication Date Title
PT81000A (en) Process for the preparation of heterocyclic derivatives
EP0243898A3 (en) Circuit for series compensation of amplifier non-linearities
AU1185383A (en) Heterocyclic normonyl derivatives
AU2279383A (en) Pharmaceutical compositions of buspirone
EP0160925A3 (en) N-substituted neuraminic acid derivatives and process for preparation thereof
ES8402820A1 (es) 4-difenilmetil-1-((oxoalquil)imino)metil-piperidinas y sus derivados.
AU534390B2 (en) Feeder voltage compensation
AP8800109A0 (en) "Heterocyclic insecticides".
NO162758C (no) Fremgangsmaate til fjernelse av kadmium fra raafosfat.
GB2149248B (en) Offset compensation of amplifiers
IL97954A0 (en) Elimination of cadmium from phosphoric acid
GR65192B (en) Substituted n-iminomethylpiperidines are disclosed which are useful for the inhibition of gastric acid secretion
ZA856671B (en) N-substituted derivatives of 2-(pyridylaklenesulfinyl)benzimidazoles as gastric antisecretory agents
NO862902L (no) Fremgangsmaate for fjerning av lignin fra blekeriavloepsvann
AU3208884A (en) Alkylenephosphoric acid piperazine derivatives as cement set retarders
JPS54107657A (en) Zeroopoint compensating circuit for dc amplifier
ZA853759B (en) Tetrahydronaphthalenols for the treatment of hypertension
DE3262346D1 (en) Method and circuit for the compensation of induced interference voltages
AU530684B2 (en) Inhibition of gastric acid secretion
IE842546L (en) Deoxygenation of cephalosporin 1-oxides
HUT43445A (en) Circuit arrangement for compensating the non-linearity of amplifying circuits
GB8307405D0 (en) Derivatives of nitrogencontaining heterocycles
PL263901A1 (en) Circuit arrangement of the external transmitter for implanted stimulators
GB8717996D0 (en) Stacking of coal &c
HUT38478A (en) Circuit arrangement for protecting the output of high-frequency amplifiers