ES8307795A1 - Gastrointestinal-activepyrazolo-benza:di:azepine(s) - Google Patents
Gastrointestinal-activepyrazolo-benza:di:azepine(s)Info
- Publication number
- ES8307795A1 ES8307795A1 ES509227A ES509227A ES8307795A1 ES 8307795 A1 ES8307795 A1 ES 8307795A1 ES 509227 A ES509227 A ES 509227A ES 509227 A ES509227 A ES 509227A ES 8307795 A1 ES8307795 A1 ES 8307795A1
- Authority
- ES
- Spain
- Prior art keywords
- derivs
- formula
- tetraaza
- cpds
- tricyclic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Prepn. of pyrazolo-benzadiazepin (derivs.) of the formula (I) (where R1 is H or methyl; R2 is methyl or ethyl; and n is 2 or 3) is claimed. - The process comprises (i) methylating or ethylating the corresponding piperazinyl-tetraaza tricyclic cpds; or (ii) acylating the tetraaza tricyclic cpds. of the formula (II) (where R' is as above) with acetic acid derivs. of the formula (III) (where R2 and n are as above and Z is an exit gp.). Opt. the obtd. bases are converted to a and adduct salts or the acid adduct salts are converted to free bases or pharmacologically acceptable acid adduct salts. - (I) and their derivs. are gastrointestinally active. (First abstract equivalent to DK8200439-A) (Previously notified in Week 8349)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH64981 | 1981-02-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8307795A1 true ES8307795A1 (en) | 1983-08-01 |
| ES509227A0 ES509227A0 (en) | 1983-08-01 |
Family
ID=4191926
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES509227A Granted ES509227A0 (en) | 1981-02-02 | 1982-02-01 | "PROCEDURE FOR THE PREPARATION OF METHYL- AND ETHYL-PIPERAZINYLTETRAAZATRICICLES". |
| ES520850A Granted ES520850A0 (en) | 1981-02-02 | 1983-03-22 | PROCEDURE FOR THE PREPARATION OF METHYL- AND ETHYL-PIPERAZINYLTETRAAZATRICICLES. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES520850A Granted ES520850A0 (en) | 1981-02-02 | 1983-03-22 | PROCEDURE FOR THE PREPARATION OF METHYL- AND ETHYL-PIPERAZINYLTETRAAZATRICICLES. |
Country Status (7)
| Country | Link |
|---|---|
| DK (1) | DK43982A (en) |
| ES (2) | ES509227A0 (en) |
| FI (1) | FI820314L (en) |
| GR (1) | GR74735B (en) |
| HU (1) | HU185087B (en) |
| NO (1) | NO820304L (en) |
| PT (1) | PT74368B (en) |
-
1982
- 1982-02-01 ES ES509227A patent/ES509227A0/en active Granted
- 1982-02-01 GR GR67173A patent/GR74735B/el unknown
- 1982-02-01 FI FI820314A patent/FI820314L/en not_active Application Discontinuation
- 1982-02-01 NO NO820304A patent/NO820304L/en unknown
- 1982-02-01 PT PT7436882A patent/PT74368B/en unknown
- 1982-02-01 DK DK43982A patent/DK43982A/en not_active Application Discontinuation
- 1982-02-01 HU HU29382A patent/HU185087B/en unknown
-
1983
- 1983-03-22 ES ES520850A patent/ES520850A0/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| GR74735B (en) | 1984-07-11 |
| ES8404350A1 (en) | 1984-05-01 |
| NO820304L (en) | 1982-08-03 |
| HU185087B (en) | 1984-11-28 |
| ES509227A0 (en) | 1983-08-01 |
| DK43982A (en) | 1982-08-03 |
| PT74368A (en) | 1982-03-01 |
| FI820314L (en) | 1982-08-03 |
| ES520850A0 (en) | 1984-05-01 |
| PT74368B (en) | 1984-10-22 |
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