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Merck and Co Inc
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Merck and Co Inc
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Filing date
Publication date
Application filed by Merck and Co IncfiledCriticalMerck and Co Inc
Publication of ES8307784A1publicationCriticalpatent/ES8307784A1/es
Publication of ES513931A0publicationCriticalpatent/ES513931A0/es
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE ESTERES METILICOS DE (5-ALQUIL-2-OXO-1,3-DIOXOLEN-4-IL), DONDE EL GRUPO ALQUILICO TIENE 1 A 6 ATOMOS DE CARBONO, DE COMPUESTOS QUE CONTIENEN GRUPO CARBOXILICO. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (I), EN LA QUE R ES ALQUILO C<1<-<6, CON UN COMPUESTO QUE CONTIENE GRUPO CARBOXILICO, EN FORMA DE ACIDO LIBRE O SAL DE LITRO O PLATA. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE 0 C Y 50 C. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO ANTIBIOTICOS Y ANTIHIPERTENSIVOS.
ES513931A1981-07-131982-07-13Un procedimiento para la preparacion de esteres metilicos de (5-alquil-2-oxo-1,3-dioxolen-4-il)
GrantedES513931A0
(es)
Foerfarande foer framstaellning av d-2-(6-metoxi-2-naftyl)-propionsyra och dess farmaceutiskt godtagbara salter samt av nya mellanprodukter anvaenda vid deras framstaellning
Anvendelse av et hjelpestoff som tilsetning til beta-laktamantibiotikum for aa oeke absorpsjonsgraden av antibiotikumet i blodet ved oral administrering.
Analogifremgangsmaate for fremstilling av terapeutisk aktiv ester av 7beta-(2-(2-amino-tiazol-4-yl)acetamido)-3-(((1-(2-dimetylamino-etyl)-1h-tetrazol-5-yl)tio)metyl)-cef-3-em-4-karboksylsyre.
7-(-amino(5,6-dihydro-1,4-dithin and 1,4-oxathiin-2-yl)acetamido) cephalosporanic and desacetoxy cephalosporanic acids and esters, processes for their preparation and pharmaceutical compositions containing them
Analogifremgangsmaade til fremstilling af benzoxazol- eller benzthiazol-2-carboxylsyreestere eller farmaceutisk acceptable syreadditionssalte eller aminosyre- eller glucuronsyrekonjugatsalte heraf