ES8305308A1 - Process for the production of an amide of a D-amino acid - Google Patents
Process for the production of an amide of a D-amino acidInfo
- Publication number
- ES8305308A1 ES8305308A1 ES513405A ES513405A ES8305308A1 ES 8305308 A1 ES8305308 A1 ES 8305308A1 ES 513405 A ES513405 A ES 513405A ES 513405 A ES513405 A ES 513405A ES 8305308 A1 ES8305308 A1 ES 8305308A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- alkyl
- ethyl
- image
- methyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Peptides Or Proteins (AREA)
- Seasonings (AREA)
Abstract
Amides of dipeptides of L-aspartyl-D-amino acid of formula: <IMAGE> and their addition salts with acids and physiologically acceptable cations where Ra is CH2OH or CH2OCH3, R is a branched radical selected from the group comprising phenkyl, diisopropyl carbinyl, d-methyl-t-butyl carbinyl, d-ethyl-t-butyl carbinyl, di-t-butyl carbinyl, 2- methylthio-2,4-dimethyl pentan-2-yl, <IMAGE> where at least one of the radicals R3, R4, R5 and R6 is alkyl having from 1 to 4 carbon atoms and the remainder are hydrogen or alkyl having from 1 to 4 carbon atoms, X is O, S, SO, SO2, C=O or CHOH, m is 0 or 1-4, n and p are each 0, 1, 2 or 3, where the sum of n + p is not greater than 3 and the sum of the carbon atoms in R3, R4, R5 and R6 is not more than 6 and when R3 and R4 or R5 and R6 are both ethyl, they are then methyl or ethyl, <IMAGE> where one of the radicals R7, R8 or R9 is alkyl from 1 to 4 carbon atoms and the remainder are hydrogen or alkyl having from 1 to 4 carbon atoms and the sum of the carbon atoms in R7, R8 and R9 is not more than 6, m and q are the same or different and each have the values previously specified for m, <IMAGE> where each of the radicals R12 and R13 is methyl or ethyl or R12 is hydrogen and R13 is alkyl having from 1 to 4 carbon atoms, Z is O or NH and t is 1 or 2, <IMAGE> where w is 1-4, R14 and R16 are each alkyl having from 1 to 4 carbon atoms, R15 is H, OH, methyl or ethyl and the sum of the carbon atoms in R14, R15 and R16 is not more than 6 and when R14 and R15 are both alkyl, then they are methyl or ethyl and <IMAGE> where R17 and R19 are alkyl having from 1 to 4 carbon atoms, R18 and R20 are H or alkyl with 1 or 2 carbon atoms, A is OH and B is H, OH or CH3 and A and B when joined together represent radicals of formula <IMAGE> in which the sum of the carbon atoms in R17, R18, R19 and R20 is not more than 6 and when R17 and R18 or R19 and R20 are both alkyl, they are then methyl or ethyl; these amides are powerful sweeteners which have advantages over the prior art; the invention also relates to edible compositions containing these amides, methods for their use in edible compositions and new amide intermediaries useful in their production.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES513405A ES8305308A1 (en) | 1982-06-23 | 1982-06-23 | Process for the production of an amide of a D-amino acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES513405A ES8305308A1 (en) | 1982-06-23 | 1982-06-23 | Process for the production of an amide of a D-amino acid |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES513405A0 ES513405A0 (en) | 1983-04-01 |
| ES8305308A1 true ES8305308A1 (en) | 1983-04-01 |
Family
ID=8484367
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES513405A Expired ES8305308A1 (en) | 1982-06-23 | 1982-06-23 | Process for the production of an amide of a D-amino acid |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES8305308A1 (en) |
-
1982
- 1982-06-23 ES ES513405A patent/ES8305308A1/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES513405A0 (en) | 1983-04-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NZ240050A (en) | Substituted piperazine derivatives; pharmaceutical compositions and preparatory processes | |
| RU94046457A (en) | Aspartam derivatives, process for preparation thereof and sweetening agent that contains said derivatives | |
| DE3062609D1 (en) | Muramyldipeptide derivatives, process for preparing said compounds and pharmaceutical compositions containing said compounds | |
| JPS5681561A (en) | Anilide derivative* its manufacture and its use | |
| DE3070912D1 (en) | Pharmaceutical heterocyclic compounds, processes for their preparation and compositions containing them | |
| ES8303291A1 (en) | Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions. | |
| DE3372362D1 (en) | Polyprenylcarboxylic acid amides and process for preparing the same | |
| IE800669L (en) | Cephalosporins. | |
| IL92660A0 (en) | Enzyme-inhibiting amino acid derivatives,a process for the preparation thereof,compositions containing these,and the use thereof | |
| HU9303406D0 (en) | 15-deoxyspergualin analogs and their method of preparation | |
| JPS5368721A (en) | Disubstd. aliphatic carboxylic acid amide amines, and detergents and cosmeticcompositions containing the same | |
| ES8305308A1 (en) | Process for the production of an amide of a D-amino acid | |
| DE3165993D1 (en) | Salts of endo-8-methyl-8-syn-alkyl-8-azoniabicyclo-(3.2.1)-octane-3-alkylcarboxylates, process for their preparation and therapeutic compositions containing them | |
| ES8204413A1 (en) | Process for the production of a dipeptide amide of an L-aspartyl-D-amino acid | |
| PT85978A (en) | PROCESS FOR THE PREPARATION OF POLYFLUORIN COMPOUNDS | |
| ES8504182A1 (en) | Piperidinoquinoxaline derivatives, their preparation and use. | |
| ES8305699A1 (en) | Process for the production of a dipeptide amide of an L-aspartyl-D-amino acid | |
| DE3475402D1 (en) | Endo-8,8-dialkyl-8-azoniabicyclo (3.2.1) octane-6,7-exo-epoxy-3-alkyl-carboxylate salts, a process for their preparation, and therapeutic compositions which contain them as active principle | |
| CH612180A5 (en) | Process for the preparation of novel pyroglutamyl compounds | |
| GB881510A (en) | Iodine-containing benzoic acid amides and a method of producing same | |
| EP0331756A4 (en) | Agents for prophylaxis and treatment of thrombopenia |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC1A | Transfer granted |