ES8304058A1 - 3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic Acid - Google Patents
3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic AcidInfo
- Publication number
- ES8304058A1 ES8304058A1 ES509913A ES509913A ES8304058A1 ES 8304058 A1 ES8304058 A1 ES 8304058A1 ES 509913 A ES509913 A ES 509913A ES 509913 A ES509913 A ES 509913A ES 8304058 A1 ES8304058 A1 ES 8304058A1
- Authority
- ES
- Spain
- Prior art keywords
- tetramethyl
- hexadecapentaenoic acid
- hexadecapentaenoic
- acid
- keratinisation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- UUBHZHZSIKRVIV-KCXSXWJSSA-N (2e,6e,10e)-3,7,11,15-tetramethylhexadeca-2,4,6,10,14-pentaenoic acid Chemical compound CC(C)=CCC\C(C)=C\CC\C(C)=C\C=C\C(\C)=C\C(O)=O UUBHZHZSIKRVIV-KCXSXWJSSA-N 0.000 title abstract 2
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004494 ethyl ester group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 208000017520 skin disease Diseases 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
- C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Emergency Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Dermatology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic acid and its salts are anticancer agents and therapeutic agents for treatment of skin diseases with keratinisation. The preparation of the ethyl ester is described.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4455880A JPS56140949A (en) | 1980-04-07 | 1980-04-07 | 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid |
JP10442080A JPS5731615A (en) | 1980-07-31 | 1980-07-31 | Remedy for skin disease with keratinization |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8304058A1 true ES8304058A1 (en) | 1983-02-16 |
ES509913A0 ES509913A0 (en) | 1983-02-16 |
Family
ID=26384501
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES501124A Granted ES501124A0 (en) | 1980-04-07 | 1981-04-06 | A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10-14-HEXADECAPENTAENOICO. |
ES509913A Granted ES509913A0 (en) | 1980-04-07 | 1982-02-25 | A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10,14-HEXADECAPENTAENOICO. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES501124A Granted ES501124A0 (en) | 1980-04-07 | 1981-04-06 | A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10-14-HEXADECAPENTAENOICO. |
Country Status (11)
Country | Link |
---|---|
AU (1) | AU537402B2 (en) |
CA (1) | CA1179370A (en) |
CH (1) | CH646682A5 (en) |
DE (1) | DE3113149A1 (en) |
DK (1) | DK158457C (en) |
ES (2) | ES501124A0 (en) |
FR (1) | FR2479807A1 (en) |
GB (1) | GB2073750B (en) |
IT (1) | IT1194141B (en) |
NL (1) | NL191744C (en) |
SE (1) | SE447243B (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56140949A (en) * | 1980-04-07 | 1981-11-04 | Eisai Co Ltd | 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid |
DE3163920D1 (en) * | 1980-12-24 | 1984-07-05 | Eisai Co Ltd | Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases |
JPS57106638A (en) * | 1980-12-24 | 1982-07-02 | Eisai Co Ltd | Conjugated polyprenylcarboxylic acid and its derivative |
JPS58164508A (en) * | 1982-03-26 | 1983-09-29 | Eisai Co Ltd | Composition for external use containing isoprenyl-carboxylic acid |
JPS5973516A (en) * | 1982-10-21 | 1984-04-25 | Eisai Co Ltd | Antiphlogistic agent |
JPS6160612A (en) * | 1984-08-31 | 1986-03-28 | Eisai Co Ltd | Carcinostatic intensifier |
IL107587A (en) * | 1993-11-12 | 1998-08-16 | Univ Ramot | Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation |
WO2001080854A1 (en) | 2000-04-24 | 2001-11-01 | Nikken Chemicals Co., Ltd. | Activators for peroxisome proliferator-activated receptor |
CN116041172B (en) * | 2023-02-01 | 2024-08-02 | 宝鸡文理学院 | Preparation method of nervonic acid |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2171497A5 (en) * | 1972-02-02 | 1973-09-21 | Rhone Poulenc Sa | 1,5-dimethyl-1,5-hexadienylidene sulphone derivs - - intermediates for terpenes |
JPS52131507A (en) * | 1976-04-24 | 1977-11-04 | Sankyo Co Ltd | Polyprenyl derivatives |
-
1981
- 1981-04-01 NL NL8101630A patent/NL191744C/en not_active IP Right Cessation
- 1981-04-01 DE DE19813113149 patent/DE3113149A1/en active Granted
- 1981-04-01 GB GB8110160A patent/GB2073750B/en not_active Expired
- 1981-04-03 SE SE8102161A patent/SE447243B/en not_active IP Right Cessation
- 1981-04-06 FR FR8106874A patent/FR2479807A1/en active Granted
- 1981-04-06 ES ES501124A patent/ES501124A0/en active Granted
- 1981-04-06 DK DK155081A patent/DK158457C/en not_active IP Right Cessation
- 1981-04-06 CA CA000374715A patent/CA1179370A/en not_active Expired
- 1981-04-06 CH CH231781A patent/CH646682A5/en not_active IP Right Cessation
- 1981-04-07 AU AU69159/81A patent/AU537402B2/en not_active Ceased
- 1981-04-07 IT IT20967/81A patent/IT1194141B/en active
-
1982
- 1982-02-25 ES ES509913A patent/ES509913A0/en active Granted
Also Published As
Publication number | Publication date |
---|---|
NL8101630A (en) | 1981-11-02 |
DE3113149A1 (en) | 1982-01-28 |
FR2479807A1 (en) | 1981-10-09 |
FR2479807B1 (en) | 1984-07-20 |
ES509913A0 (en) | 1983-02-16 |
DK158457B (en) | 1990-05-21 |
ES8205190A1 (en) | 1982-06-01 |
IT8120967A0 (en) | 1981-04-07 |
DK158457C (en) | 1990-10-08 |
DK155081A (en) | 1981-10-08 |
GB2073750A (en) | 1981-10-21 |
CA1179370A (en) | 1984-12-11 |
IT1194141B (en) | 1988-09-14 |
SE8102161L (en) | 1981-10-08 |
DE3113149C2 (en) | 1988-11-10 |
AU6915981A (en) | 1981-10-15 |
GB2073750B (en) | 1984-02-22 |
ES501124A0 (en) | 1982-06-01 |
NL191744C (en) | 1996-06-04 |
NL191744B (en) | 1996-02-01 |
AU537402B2 (en) | 1984-06-21 |
CH646682A5 (en) | 1984-12-14 |
SE447243B (en) | 1986-11-03 |
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