ES8304058A1 - 3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic Acid - Google Patents

3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic Acid

Info

Publication number
ES8304058A1
ES8304058A1 ES509913A ES509913A ES8304058A1 ES 8304058 A1 ES8304058 A1 ES 8304058A1 ES 509913 A ES509913 A ES 509913A ES 509913 A ES509913 A ES 509913A ES 8304058 A1 ES8304058 A1 ES 8304058A1
Authority
ES
Spain
Prior art keywords
tetramethyl
hexadecapentaenoic acid
hexadecapentaenoic
acid
keratinisation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES509913A
Other languages
Spanish (es)
Other versions
ES509913A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4455880A external-priority patent/JPS56140949A/en
Priority claimed from JP10442080A external-priority patent/JPS5731615A/en
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of ES8304058A1 publication Critical patent/ES8304058A1/en
Publication of ES509913A0 publication Critical patent/ES509913A0/en
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • C07C317/44Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03Monocarboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/587Monocarboxylic acid esters having at least two carbon-to-carbon double bonds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic acid and its salts are anticancer agents and therapeutic agents for treatment of skin diseases with keratinisation. The preparation of the ethyl ester is described.
ES509913A 1980-04-07 1982-02-25 A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10,14-HEXADECAPENTAENOICO. Granted ES509913A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4455880A JPS56140949A (en) 1980-04-07 1980-04-07 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid
JP10442080A JPS5731615A (en) 1980-07-31 1980-07-31 Remedy for skin disease with keratinization

Publications (2)

Publication Number Publication Date
ES8304058A1 true ES8304058A1 (en) 1983-02-16
ES509913A0 ES509913A0 (en) 1983-02-16

Family

ID=26384501

Family Applications (2)

Application Number Title Priority Date Filing Date
ES501124A Granted ES501124A0 (en) 1980-04-07 1981-04-06 A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10-14-HEXADECAPENTAENOICO.
ES509913A Granted ES509913A0 (en) 1980-04-07 1982-02-25 A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10,14-HEXADECAPENTAENOICO.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES501124A Granted ES501124A0 (en) 1980-04-07 1981-04-06 A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10-14-HEXADECAPENTAENOICO.

Country Status (11)

Country Link
AU (1) AU537402B2 (en)
CA (1) CA1179370A (en)
CH (1) CH646682A5 (en)
DE (1) DE3113149A1 (en)
DK (1) DK158457C (en)
ES (2) ES501124A0 (en)
FR (1) FR2479807A1 (en)
GB (1) GB2073750B (en)
IT (1) IT1194141B (en)
NL (1) NL191744C (en)
SE (1) SE447243B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56140949A (en) * 1980-04-07 1981-11-04 Eisai Co Ltd 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid
DE3163920D1 (en) * 1980-12-24 1984-07-05 Eisai Co Ltd Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases
JPS57106638A (en) * 1980-12-24 1982-07-02 Eisai Co Ltd Conjugated polyprenylcarboxylic acid and its derivative
JPS58164508A (en) * 1982-03-26 1983-09-29 Eisai Co Ltd Composition for external use containing isoprenyl-carboxylic acid
JPS5973516A (en) * 1982-10-21 1984-04-25 Eisai Co Ltd Antiphlogistic agent
JPS6160612A (en) * 1984-08-31 1986-03-28 Eisai Co Ltd Carcinostatic intensifier
IL107587A (en) * 1993-11-12 1998-08-16 Univ Ramot Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation
WO2001080854A1 (en) 2000-04-24 2001-11-01 Nikken Chemicals Co., Ltd. Activators for peroxisome proliferator-activated receptor
CN116041172B (en) * 2023-02-01 2024-08-02 宝鸡文理学院 Preparation method of nervonic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2171497A5 (en) * 1972-02-02 1973-09-21 Rhone Poulenc Sa 1,5-dimethyl-1,5-hexadienylidene sulphone derivs - - intermediates for terpenes
JPS52131507A (en) * 1976-04-24 1977-11-04 Sankyo Co Ltd Polyprenyl derivatives

Also Published As

Publication number Publication date
NL8101630A (en) 1981-11-02
DE3113149A1 (en) 1982-01-28
FR2479807A1 (en) 1981-10-09
FR2479807B1 (en) 1984-07-20
ES509913A0 (en) 1983-02-16
DK158457B (en) 1990-05-21
ES8205190A1 (en) 1982-06-01
IT8120967A0 (en) 1981-04-07
DK158457C (en) 1990-10-08
DK155081A (en) 1981-10-08
GB2073750A (en) 1981-10-21
CA1179370A (en) 1984-12-11
IT1194141B (en) 1988-09-14
SE8102161L (en) 1981-10-08
DE3113149C2 (en) 1988-11-10
AU6915981A (en) 1981-10-15
GB2073750B (en) 1984-02-22
ES501124A0 (en) 1982-06-01
NL191744C (en) 1996-06-04
NL191744B (en) 1996-02-01
AU537402B2 (en) 1984-06-21
CH646682A5 (en) 1984-12-14
SE447243B (en) 1986-11-03

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