ES8205190A1 - 3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic Acid - Google Patents

3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic Acid

Info

Publication number
ES8205190A1
ES8205190A1 ES501124A ES501124A ES8205190A1 ES 8205190 A1 ES8205190 A1 ES 8205190A1 ES 501124 A ES501124 A ES 501124A ES 501124 A ES501124 A ES 501124A ES 8205190 A1 ES8205190 A1 ES 8205190A1
Authority
ES
Spain
Prior art keywords
tetramethyl
hexadecapentaenoic acid
hexadecapentaenoic
acid
keratinisation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES501124A
Other languages
Spanish (es)
Other versions
ES501124A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4455880A external-priority patent/JPS56140949A/en
Priority claimed from JP10442080A external-priority patent/JPS5731615A/en
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of ES8205190A1 publication Critical patent/ES8205190A1/en
Publication of ES501124A0 publication Critical patent/ES501124A0/en
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/52—Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
    • C07C69/587—Monocarboxylic acid esters having at least two carbon-to-carbon double bonds

Abstract

3,7,11,15-Tetramethyl- 2,4,6,10,14-hexadecapentaenoic acid and its salts are anticancer agents and therapeutic agents for treatment of skin diseases with keratinisation. The preparation of the ethyl ester is described.
ES501124A 1980-04-07 1981-04-06 A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10-14-HEXADECAPENTAENOICO. Granted ES501124A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4455880A JPS56140949A (en) 1980-04-07 1980-04-07 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid
JP10442080A JPS5731615A (en) 1980-07-31 1980-07-31 Remedy for skin disease with keratinization

Publications (2)

Publication Number Publication Date
ES8205190A1 true ES8205190A1 (en) 1982-06-01
ES501124A0 ES501124A0 (en) 1982-06-01

Family

ID=26384501

Family Applications (2)

Application Number Title Priority Date Filing Date
ES501124A Granted ES501124A0 (en) 1980-04-07 1981-04-06 A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10-14-HEXADECAPENTAENOICO.
ES509913A Granted ES509913A0 (en) 1980-04-07 1982-02-25 A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10,14-HEXADECAPENTAENOICO.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES509913A Granted ES509913A0 (en) 1980-04-07 1982-02-25 A PROCEDURE FOR THE PREPARATION OF ACID 3,7,11,15-TETRAMETIL-2,4,6,10,14-HEXADECAPENTAENOICO.

Country Status (11)

Country Link
AU (1) AU537402B2 (en)
CA (1) CA1179370A (en)
CH (1) CH646682A5 (en)
DE (1) DE3113149A1 (en)
DK (1) DK158457C (en)
ES (2) ES501124A0 (en)
FR (1) FR2479807A1 (en)
GB (1) GB2073750B (en)
IT (1) IT1194141B (en)
NL (1) NL191744C (en)
SE (1) SE447243B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56140949A (en) * 1980-04-07 1981-11-04 Eisai Co Ltd 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenic acid
JPS57106638A (en) * 1980-12-24 1982-07-02 Eisai Co Ltd Conjugated polyprenylcarboxylic acid and its derivative
DE3163920D1 (en) * 1980-12-24 1984-07-05 Eisai Co Ltd Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases
JPS58164508A (en) * 1982-03-26 1983-09-29 Eisai Co Ltd Composition for external use containing isoprenyl-carboxylic acid
JPS5973516A (en) * 1982-10-21 1984-04-25 Eisai Co Ltd Antiphlogistic agent
JPS6160612A (en) * 1984-08-31 1986-03-28 Eisai Co Ltd Carcinostatic intensifier
IL107587A (en) * 1993-11-12 1998-08-16 Univ Ramot Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation
CA2407421C (en) 2000-04-24 2009-11-03 Nikken Chemicals Co., Ltd. Activators of peroxisome proliferator-activated receptors
CN116041172A (en) * 2023-02-01 2023-05-02 宝鸡文理学院 Preparation method of nervonic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2171497A5 (en) * 1972-02-02 1973-09-21 Rhone Poulenc Sa 1,5-dimethyl-1,5-hexadienylidene sulphone derivs - - intermediates for terpenes
JPS52131507A (en) * 1976-04-24 1977-11-04 Sankyo Co Ltd Polyprenyl derivatives

Also Published As

Publication number Publication date
AU537402B2 (en) 1984-06-21
DK158457C (en) 1990-10-08
DE3113149A1 (en) 1982-01-28
FR2479807A1 (en) 1981-10-09
DE3113149C2 (en) 1988-11-10
GB2073750B (en) 1984-02-22
SE8102161L (en) 1981-10-08
NL8101630A (en) 1981-11-02
CA1179370A (en) 1984-12-11
IT8120967A0 (en) 1981-04-07
FR2479807B1 (en) 1984-07-20
NL191744B (en) 1996-02-01
SE447243B (en) 1986-11-03
ES8304058A1 (en) 1983-02-16
DK158457B (en) 1990-05-21
DK155081A (en) 1981-10-08
IT1194141B (en) 1988-09-14
CH646682A5 (en) 1984-12-14
AU6915981A (en) 1981-10-15
NL191744C (en) 1996-06-04
ES509913A0 (en) 1983-02-16
ES501124A0 (en) 1982-06-01
GB2073750A (en) 1981-10-21

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000301