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SCIENT ET IND de l ILE FR SOC
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SCIENT ET IND de l ILE FR SOC
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Priority to ES511814ApriorityCriticalpatent/ES8303330A1/es
Publication of ES511814A0publicationCriticalpatent/ES511814A0/es
Publication of ES8303330A1publicationCriticalpatent/ES8303330A1/es
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE LA N-(1-PROPIL-2-PIRROLIDINILMETIL)-2-METOXI-5-SULFAMOIL-BENZAMIDA, DE SUS SALES DE AMONIO CUATERNARIO, SU N-OXIDO, ISOMEROS Y SALES DE ADICION DE ACIDOS FISIOLOGICAMENTE COMPATIBLES. CONSISTE EN LA REACCION DE ACIDO 2-METOXI-5-SULFAMOILBENZOICO, O UNO DE SUS DERIVADOS REACTIVOS, CON 1-PROPIL-2-AMINOMETIL-PIRROLIDINA O UNO DE SUS DERIVADOS REACTIVOS. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE POLAR, TAL COMO GLICOL ATILENICO, A UNA TEMPERATURA ENTRE 50-55 C. EL PRODUCTO OBTENIDO SE CRISTALIZA MEDIANTE ADICION DE AGUA. ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS COMO ANTIDEPRESIVO.
ES511814A1982-04-291982-04-29"procedimiento de preparacion del n-(1-propil-2-pirrolidinilmetil)-2-metoxi-5-sulfamoil-benzamida".
ExpiredES8303330A1
(es)