ES8302705A1 - Manufacture of 11-(2'-substituted)acetyl- 5, 11-dihydro-6h-pyrido-(2,3-b)(1,4)- benzodiazepine-6-one or acid addition salt of same - Google Patents
Manufacture of 11-(2'-substituted)acetyl- 5, 11-dihydro-6h-pyrido-(2,3-b)(1,4)- benzodiazepine-6-one or acid addition salt of sameInfo
- Publication number
- ES8302705A1 ES8302705A1 ES510887A ES510887A ES8302705A1 ES 8302705 A1 ES8302705 A1 ES 8302705A1 ES 510887 A ES510887 A ES 510887A ES 510887 A ES510887 A ES 510887A ES 8302705 A1 ES8302705 A1 ES 8302705A1
- Authority
- ES
- Spain
- Prior art keywords
- pyrido
- dihydro
- acetyl
- substituted
- benzodiazepine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A process for the preparation of 11-(2'-substituted)acetyl- 5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-ones of the general formula I and of their pharmaceutically tolerable salts is given by preparation of the corresponding benzodiazepine N-oxides of the general formula II and reduction of the pyrido-N-oxide group to the pyrido group.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20245/81A IT1194766B (en) | 1981-03-10 | 1981-03-10 | PROCESS FOR THE PREPARATION OF 11- (2'-REPLACED) -ACETYL-5,11-DIHYDRO-6H-PYRIDO- (2,3-B) (1,4) -BENZODIAZEPIN-6-ONI |
Publications (2)
Publication Number | Publication Date |
---|---|
ES510887A0 ES510887A0 (en) | 1983-02-01 |
ES8302705A1 true ES8302705A1 (en) | 1983-02-01 |
Family
ID=11165098
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES510887A Expired ES8302705A1 (en) | 1981-03-10 | 1982-03-09 | Manufacture of 11-(2'-substituted)acetyl- 5, 11-dihydro-6h-pyrido-(2,3-b)(1,4)- benzodiazepine-6-one or acid addition salt of same |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS57167984A (en) |
DE (1) | DE3208656A1 (en) |
ES (1) | ES8302705A1 (en) |
GR (1) | GR75888B (en) |
IT (1) | IT1194766B (en) |
NL (1) | NL8201001A (en) |
SE (1) | SE8201514L (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1212743B (en) * | 1983-05-17 | 1989-11-30 | Dompe Farmaceutici Spa | QUATERNARY SALTS OF BENZO DERIVATIVES [1,4] DIAZEPINONICS, PYRID [1,4] BENZODIAZEPINONICS, PRIDO [1,5] BENZODIAZEPINONICS AND THEIR PHARMACOLOGICAL LIFE ACTS |
IT1212742B (en) * | 1983-05-17 | 1989-11-30 | Dompe Farmaceutici Spa | DIBENZO DERIVATIVES [1,4] PYRID DIAZEPINONIC [1,4] BENZODIAZEPINONIC, PYRID [1,5] BENZODIAZEPINONIC AND THEIR PHARMACOLOGICAL ACTIVITY |
CA2052946A1 (en) * | 1990-10-19 | 1992-04-20 | Karl G. Grozinger | Method for the preparation of 5,11-dihydro-6h-dipyrido ¬3,2-b:2', 3'-e| ¬1,4|diazepines |
-
1981
- 1981-03-10 IT IT20245/81A patent/IT1194766B/en active
-
1982
- 1982-03-08 GR GR67518A patent/GR75888B/el unknown
- 1982-03-09 ES ES510887A patent/ES8302705A1/en not_active Expired
- 1982-03-10 DE DE19823208656 patent/DE3208656A1/en not_active Withdrawn
- 1982-03-10 JP JP57038825A patent/JPS57167984A/en active Pending
- 1982-03-10 NL NL8201001A patent/NL8201001A/en not_active Application Discontinuation
- 1982-03-10 SE SE8201514A patent/SE8201514L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ES510887A0 (en) | 1983-02-01 |
IT8120245A0 (en) | 1981-03-10 |
IT8120245A1 (en) | 1982-09-10 |
JPS57167984A (en) | 1982-10-16 |
NL8201001A (en) | 1982-10-01 |
DE3208656A1 (en) | 1982-10-21 |
GR75888B (en) | 1984-08-02 |
IT1194766B (en) | 1988-09-28 |
SE8201514L (en) | 1982-09-11 |
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