ES8304130A1 - Manufacture of pyrido-(2,3-b)-(1,4)-benzodiazepines - Google Patents
Manufacture of pyrido-(2,3-b)-(1,4)-benzodiazepinesInfo
- Publication number
- ES8304130A1 ES8304130A1 ES511647A ES511647A ES8304130A1 ES 8304130 A1 ES8304130 A1 ES 8304130A1 ES 511647 A ES511647 A ES 511647A ES 511647 A ES511647 A ES 511647A ES 8304130 A1 ES8304130 A1 ES 8304130A1
- Authority
- ES
- Spain
- Prior art keywords
- pyrido
- benzodiazepines
- manufacture
- image
- dehydration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- RYCQVMPEIVZMII-UHFFFAOYSA-N 11h-pyrido[2,3-b][1,4]benzodiazepine Chemical class C1=NC2=CC=CN=C2NC2=CC=CC=C21 RYCQVMPEIVZMII-UHFFFAOYSA-N 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 230000018044 dehydration Effects 0.000 abstract 2
- 238000006297 dehydration reaction Methods 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- LDZJARBEIDPEEY-UHFFFAOYSA-N pyrido[2,3-b][1,4]benzodiazepin-2-one Chemical compound C1=C2C=CC=CC2=NC2=NC(=O)C=CC2=N1 LDZJARBEIDPEEY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/74—Oxygen atoms
- C07D211/76—Oxygen atoms attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
The invention relates to the preparation of pyrido[2,3-b]- [1,4]benzodiazepinone of the following formula (I): < IMAGE > by dehydration of the compound of the formula (II): < IMAGE > with metal catalysts and by means of other known dehydration systems.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT8121352A IT1211027B (en) | 1981-04-24 | 1981-04-24 | PINA PROCEDURE FOR THE PREPARATION OF _ A PYRID- [2,3-B] [1,4] BENZODIAZE |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8304130A1 true ES8304130A1 (en) | 1983-03-01 |
ES511647A0 ES511647A0 (en) | 1983-03-01 |
Family
ID=11180527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES511647A Granted ES511647A0 (en) | 1981-04-24 | 1982-04-23 | "PROCEDURE FOR THE PREPARATION OF THE PIRIDO- (2,3-B) - (1,4) -BENZODIACEPIN-6-ONA". |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS57183790A (en) |
DE (1) | DE3211973A1 (en) |
ES (1) | ES511647A0 (en) |
GR (1) | GR75993B (en) |
IT (1) | IT1211027B (en) |
NL (1) | NL8201587A (en) |
SE (1) | SE8202067L (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL97249A (en) * | 1990-02-23 | 1995-01-24 | Takeda Chemical Industries Ltd | 4,5,6,7- Tetrahydrothiazolo (5,4-b) pyridine and 5,6-dihydro-4h pyrrolo (3,2-d) thiazolo compounds, their production and pharmaceutical compositions containing them |
-
1981
- 1981-04-24 IT IT8121352A patent/IT1211027B/en active
-
1982
- 1982-03-31 SE SE8202067A patent/SE8202067L/en not_active Application Discontinuation
- 1982-03-31 DE DE19823211973 patent/DE3211973A1/en not_active Ceased
- 1982-04-15 NL NL8201587A patent/NL8201587A/en not_active Application Discontinuation
- 1982-04-19 JP JP57066169A patent/JPS57183790A/en active Pending
- 1982-04-21 GR GR67954A patent/GR75993B/el unknown
- 1982-04-23 ES ES511647A patent/ES511647A0/en active Granted
Also Published As
Publication number | Publication date |
---|---|
IT8121352A0 (en) | 1981-04-24 |
SE8202067L (en) | 1982-10-25 |
ES511647A0 (en) | 1983-03-01 |
JPS57183790A (en) | 1982-11-12 |
GR75993B (en) | 1984-08-03 |
DE3211973A1 (en) | 1982-11-11 |
IT1211027B (en) | 1989-09-29 |
NL8201587A (en) | 1982-11-16 |
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