ES8302007A1 - Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico - Google Patents
Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilicoInfo
- Publication number
- ES8302007A1 ES8302007A1 ES510270A ES510270A ES8302007A1 ES 8302007 A1 ES8302007 A1 ES 8302007A1 ES 510270 A ES510270 A ES 510270A ES 510270 A ES510270 A ES 510270A ES 8302007 A1 ES8302007 A1 ES 8302007A1
- Authority
- ES
- Spain
- Prior art keywords
- oxo
- methyl
- thio
- thiazolyl
- triazine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Cephalosporin Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE LA SAL DISODICA DEL ACIDO 7-2-(2-AMINO-4-TIAZOLIL)-2-METOXIIMINO-ACETAMIDO-3- (2,5-DIHIDRO-6-HIDROXI-2-METIL-5-OXO-AS-TRIAZIN-3-IL)TIO METI-8-OXO-5-TIA-1-AZABICICLO-4,2,0-OCT-2-ENE-2- CARBOXILICO. CONSISTE EN LA REACCION DEL ACIDO 7-AMINO CEFALOSPORANICO, QUE TIENE EL GRUPO AMINO PROTEGIDO, CON LA 2,5-DIHIDRO-6-HIDROXI-2-METIL-3-MERCAPTO-5-OXO-1,2,4-TRIAZINA, EN MEDIO ACUOSO, HIDROALCOHOLICO O HIDROACETONICO, A UNA TEMPERATURA ENTRE 35 GC Y 70 GC; SEGUIDA DE LA REACCION DE ACILACION CON CLORURO DEL ACIDO 2-(2-CLOROACETAMIDO-4-TIAZOLIL)-2-(Z)-METOXIIMINO-ACETICO, A UN PH MODERADAMENTE ACIDO Y A BAJA TEMPERATURA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIBACTERIANA.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES510270A ES8302007A1 (es) | 1982-03-10 | 1982-03-10 | Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES510270A ES8302007A1 (es) | 1982-03-10 | 1982-03-10 | Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico |
Publications (2)
Publication Number | Publication Date |
---|---|
ES510270A0 ES510270A0 (es) | 1983-01-16 |
ES8302007A1 true ES8302007A1 (es) | 1983-01-16 |
Family
ID=8483798
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES510270A Expired ES8302007A1 (es) | 1982-03-10 | 1982-03-10 | Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES8302007A1 (es) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0553792A2 (de) * | 1992-01-28 | 1993-08-04 | LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. | Verfahren zur Herstellung von Ceftriaxon-dinatriumsalzhemiheptahydrat |
WO2005105813A1 (en) * | 2004-04-28 | 2005-11-10 | Wockhardt Limited | Improved process for the manufacture of ceftriaxone sodium |
-
1982
- 1982-03-10 ES ES510270A patent/ES8302007A1/es not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0553792A2 (de) * | 1992-01-28 | 1993-08-04 | LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. | Verfahren zur Herstellung von Ceftriaxon-dinatriumsalzhemiheptahydrat |
EP0553792A3 (en) * | 1992-01-28 | 1993-12-29 | Lek Tovarna Farmacevtskih | Process for the preparation of the disodium salt hemiheptahydrate of ceftriaxone |
WO2005105813A1 (en) * | 2004-04-28 | 2005-11-10 | Wockhardt Limited | Improved process for the manufacture of ceftriaxone sodium |
Also Published As
Publication number | Publication date |
---|---|
ES510270A0 (es) | 1983-01-16 |
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