ES8302007A1 - Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico - Google Patents

Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico

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Publication number
ES8302007A1
ES8302007A1 ES510270A ES510270A ES8302007A1 ES 8302007 A1 ES8302007 A1 ES 8302007A1 ES 510270 A ES510270 A ES 510270A ES 510270 A ES510270 A ES 510270A ES 8302007 A1 ES8302007 A1 ES 8302007A1
Authority
ES
Spain
Prior art keywords
oxo
methyl
thio
thiazolyl
triazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES510270A
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English (en)
Other versions
ES510270A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Servicios y Suministros Farmaceuticos SA
Original Assignee
Servicios y Suministros Farmaceuticos SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servicios y Suministros Farmaceuticos SA filed Critical Servicios y Suministros Farmaceuticos SA
Priority to ES510270A priority Critical patent/ES510270A0/es
Publication of ES8302007A1 publication Critical patent/ES8302007A1/es
Publication of ES510270A0 publication Critical patent/ES510270A0/es
Granted legal-status Critical Current

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Abstract

PROCEDIMIENTO PARA LA OBTENCION DE LA SAL DISODICA DEL ACIDO 7-2-(2-AMINO-4-TIAZOLIL)-2-METOXIIMINO-ACETAMIDO-3- (2,5-DIHIDRO-6-HIDROXI-2-METIL-5-OXO-AS-TRIAZIN-3-IL)TIO METI-8-OXO-5-TIA-1-AZABICICLO-4,2,0-OCT-2-ENE-2- CARBOXILICO. CONSISTE EN LA REACCION DEL ACIDO 7-AMINO CEFALOSPORANICO, QUE TIENE EL GRUPO AMINO PROTEGIDO, CON LA 2,5-DIHIDRO-6-HIDROXI-2-METIL-3-MERCAPTO-5-OXO-1,2,4-TRIAZINA, EN MEDIO ACUOSO, HIDROALCOHOLICO O HIDROACETONICO, A UNA TEMPERATURA ENTRE 35 GC Y 70 GC; SEGUIDA DE LA REACCION DE ACILACION CON CLORURO DEL ACIDO 2-(2-CLOROACETAMIDO-4-TIAZOLIL)-2-(Z)-METOXIIMINO-ACETICO, A UN PH MODERADAMENTE ACIDO Y A BAJA TEMPERATURA. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIBACTERIANA.
ES510270A 1982-03-10 1982-03-10 Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico Granted ES510270A0 (es)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES510270A ES510270A0 (es) 1982-03-10 1982-03-10 Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES510270A ES510270A0 (es) 1982-03-10 1982-03-10 Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico

Publications (2)

Publication Number Publication Date
ES8302007A1 true ES8302007A1 (es) 1983-01-16
ES510270A0 ES510270A0 (es) 1983-01-16

Family

ID=8483798

Family Applications (1)

Application Number Title Priority Date Filing Date
ES510270A Granted ES510270A0 (es) 1982-03-10 1982-03-10 Procedimiento para la obtencion de la sal disodica del acido 7-(2-(2-amino-4-tiazolil)-2-metoxiimino-acetamido)-3-((2,5-dihidro-6-hidroxi-2-metil-5-oxo-as-triazin-3-il)tio)metil)-8-oxo-5-tia-1-azabiciclo (4.2.0)oct-2-ene-2-carboxilico

Country Status (1)

Country Link
ES (1) ES510270A0 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0553792A2 (de) * 1992-01-28 1993-08-04 LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. Verfahren zur Herstellung von Ceftriaxon-dinatriumsalzhemiheptahydrat
WO2005105813A1 (en) * 2004-04-28 2005-11-10 Wockhardt Limited Improved process for the manufacture of ceftriaxone sodium

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0553792A2 (de) * 1992-01-28 1993-08-04 LEK, tovarna farmacevtskih in kemicnih izdelkov, d.d. Verfahren zur Herstellung von Ceftriaxon-dinatriumsalzhemiheptahydrat
EP0553792A3 (en) * 1992-01-28 1993-12-29 Lek Tovarna Farmacevtskih Process for the preparation of the disodium salt hemiheptahydrate of ceftriaxone
WO2005105813A1 (en) * 2004-04-28 2005-11-10 Wockhardt Limited Improved process for the manufacture of ceftriaxone sodium

Also Published As

Publication number Publication date
ES510270A0 (es) 1983-01-16

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