ES8300742A1 - Un procedimiento para la preparacion de dibenzo (b,f) tiepi-nas. - Google Patents

Un procedimiento para la preparacion de dibenzo (b,f) tiepi-nas.

Info

Publication number
ES8300742A1
ES8300742A1 ES497132A ES497132A ES8300742A1 ES 8300742 A1 ES8300742 A1 ES 8300742A1 ES 497132 A ES497132 A ES 497132A ES 497132 A ES497132 A ES 497132A ES 8300742 A1 ES8300742 A1 ES 8300742A1
Authority
ES
Spain
Prior art keywords
hydroxymethyldibenzo
thiepins
carboxaldehydes
thiepin
dibenzo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497132A
Other languages
English (en)
Other versions
ES497132A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme IA Corp
Merck Sharp and Dohme Corp
Original Assignee
Merck Sharp and Dohme IA Corp
Merck Sharp and Dohme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/097,755 external-priority patent/US4237160A/en
Application filed by Merck Sharp and Dohme IA Corp, Merck Sharp and Dohme Corp filed Critical Merck Sharp and Dohme IA Corp
Publication of ES8300742A1 publication Critical patent/ES8300742A1/es
Publication of ES497132A0 publication Critical patent/ES497132A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed

Abstract

PROCEDIMIENTO DE OBTENCION DE DIBENSO (B, F)-TIEPINAS. CONSISTE EN REDUCIR UN COMPUESTO DE FORMULA GENERAL (I) POR MEDIO DE UN HIDRURO DE ALUMINIO Y UN METAL ALCALINO O BORADO. SE OBTIENE EL COMPUESTO (II) EN QUE W ES <024>CHO O <024>CH OH, M ES 0 O N-1 (CUANDO W ES <024>CHO M ES CERO Y VICEVERSA); Z ES TIO, SULFINILO O SULFONILO; R Y/O R ES HIDROGENO, HALOGENO (CLORURO, BROMO, FLUOR O IODO) AMONO, ALQUILO, ALCONOILO, HIDROXILO ALCOXI, TIOL, ALQUILOIO, ALQUILSULFINILO, ALQUILSULFONILO, TRIFLUORMETILO, CIANO, NITRO, ARALQUILO O HIDROXIALQUILO.
ES497132A 1979-11-27 1980-11-25 Un procedimiento para la preparacion de dibenzo (b,f) tiepi-nas. Granted ES497132A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9775979A 1979-11-27 1979-11-27
US06/097,755 US4237160A (en) 1979-11-27 1979-11-27 3-Hydroxymethyldibenzo[b,f]thiepins as prostaglandin antagonists

Publications (2)

Publication Number Publication Date
ES8300742A1 true ES8300742A1 (es) 1982-11-16
ES497132A0 ES497132A0 (es) 1982-11-16

Family

ID=26793604

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497132A Granted ES497132A0 (es) 1979-11-27 1980-11-25 Un procedimiento para la preparacion de dibenzo (b,f) tiepi-nas.

Country Status (7)

Country Link
EP (1) EP0029587B1 (es)
DE (1) DE3068250D1 (es)
DK (1) DK502780A (es)
ES (1) ES497132A0 (es)
GR (1) GR71609B (es)
IE (1) IE50572B1 (es)
PT (1) PT72111B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4535171A (en) * 1982-11-18 1985-08-13 Merck Frosst Canada, Inc. Dibenzo[b,f]thiepin-3-carboxaldehydes as prostaglandin antagonists
US4622403A (en) * 1983-10-11 1986-11-11 Merck Frosst Canada, Inc. 6-H dibenz[b,f]thiepin compounds
US4663307A (en) * 1983-10-26 1987-05-05 Merck Frosst Canada, Inc. Anti-allergic and anti-thromboembolic 6H-dibenz-[b,e][1,4]-oxathiepin derivatives, compositions, and method of use therefor
US5334628A (en) * 1984-06-09 1994-08-02 Kaken Pharmaceutical Co., Ltd. Amine derivatives, processes for preparing the same and fungicides containing the same
DK0805155T3 (da) * 1994-09-28 2002-07-08 Nippon Suisan Kaisha Ltd Hidtil ukendt tricyklisk, kondenseret heterocyklisk antioxidantforbindelse
WO2002056995A1 (en) * 2001-01-18 2002-07-25 Nicholas Jackson Water filter

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4205170A (en) * 1976-12-03 1980-05-27 Nippon Chemiphar Company, Limited Propionic acid derivatives
PT68303A (en) * 1977-07-26 1978-08-01 Merck & Co Inc Process for the preparation of dibenzo/b,f/thiepin
IT7850376A0 (it) * 1977-07-26 1978-07-19 Merck & Co Inc Composizioni di dibenzo(b.f)tiepina e procedimento per la loro preparazione

Also Published As

Publication number Publication date
DE3068250D1 (en) 1984-07-19
DK502780A (da) 1981-05-28
PT72111B (en) 1982-06-25
GR71609B (es) 1983-06-17
ES497132A0 (es) 1982-11-16
EP0029587B1 (en) 1984-06-13
IE802455L (en) 1981-05-27
IE50572B1 (en) 1986-05-14
EP0029587A1 (en) 1981-06-03
PT72111A (en) 1980-12-01

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