ES8300338A1 - A procedure for the preparation of derivatives of phosphinic and phosphonic acid. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the preparation of derivatives of phosphinic and phosphonic acid. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES8300338A1
ES8300338A1 ES508363A ES508363A ES8300338A1 ES 8300338 A1 ES8300338 A1 ES 8300338A1 ES 508363 A ES508363 A ES 508363A ES 508363 A ES508363 A ES 508363A ES 8300338 A1 ES8300338 A1 ES 8300338A1
Authority
ES
Spain
Prior art keywords
formula
rent
phosphinic
translation
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES508363A
Other languages
Spanish (es)
Other versions
ES508363A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Priority to ES508363A priority Critical patent/ES8300338A1/en
Publication of ES508363A0 publication Critical patent/ES508363A0/en
Publication of ES8300338A1 publication Critical patent/ES8300338A1/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for the obtaining of derivatives of phosphinic and phosphonic acids and of their salts, of formula (I), in which r is rent and r is hydrogen or lower rent, or together with the carbon atomo to which they are united form a cyclocal ring c <003>; r and r are lower rent; and x is hydrogen, hydroxyl, rent or aril. It consists in the reaction of a compound of formula (II) with a cetone of formula r cor, in which all symbols have the same meaning as in formula (I). The reaction is carried out in an aqueous-organic medium, at the reflux temperature of the reaction mixture. Diastereomeric mixing can be separated diastereomeric racematos or resolve the optical isomers. These compounds have pharmacological applications for the treatment of inflammatory states, degenerative articular diseases and wilson's disease. (Machine-translation by Google Translate, not legally binding)
ES508363A 1981-12-28 1981-12-28 A procedure for the preparation of derivatives of phosphinic and phosphonic acid. (Machine-translation by Google Translate, not legally binding) Expired ES8300338A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES508363A ES8300338A1 (en) 1981-12-28 1981-12-28 A procedure for the preparation of derivatives of phosphinic and phosphonic acid. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES508363A ES8300338A1 (en) 1981-12-28 1981-12-28 A procedure for the preparation of derivatives of phosphinic and phosphonic acid. (Machine-translation by Google Translate, not legally binding)

Publications (2)

Publication Number Publication Date
ES508363A0 ES508363A0 (en) 1982-11-01
ES8300338A1 true ES8300338A1 (en) 1982-11-01

Family

ID=8483428

Family Applications (1)

Application Number Title Priority Date Filing Date
ES508363A Expired ES8300338A1 (en) 1981-12-28 1981-12-28 A procedure for the preparation of derivatives of phosphinic and phosphonic acid. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES8300338A1 (en)

Also Published As

Publication number Publication date
ES508363A0 (en) 1982-11-01

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