ES8300318A1 - "procedimiento de preparar acidos aroilaminicos y similares". - Google Patents

"procedimiento de preparar acidos aroilaminicos y similares".

Info

Publication number
ES8300318A1
ES8300318A1 ES508706A ES508706A ES8300318A1 ES 8300318 A1 ES8300318 A1 ES 8300318A1 ES 508706 A ES508706 A ES 508706A ES 508706 A ES508706 A ES 508706A ES 8300318 A1 ES8300318 A1 ES 8300318A1
Authority
ES
Spain
Prior art keywords
cycloalkyl
hydroxy
alkyl
amino
dialkylamino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES508706A
Other languages
English (en)
Other versions
ES508706A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
USV Pharmaceutical Corp
Original Assignee
USV Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by USV Pharmaceutical Corp filed Critical USV Pharmaceutical Corp
Publication of ES8300318A1 publication Critical patent/ES8300318A1/es
Publication of ES508706A0 publication Critical patent/ES508706A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00—Thiocarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE ACIDOS AROILAMINICOS Y SIMILARES, ASI COMO DE SUS SALES DE ALCALINOS, ALCALINOTERREOS Y AMINICAS FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE N VALE DE 1 A 4; Q ES OXIGENO, AZUFRE O NH; Y LOS DEMAS SIMBOLOS PUEDEN SER VARIOS RADICALES. CONSISTE EN LA REACCION DE AMIDIFICACION ENTRE UN COMPUESTO DE FORMULA (II) Y UN AMINOACIDO DE FORMULA (III), EN LAS QUE TODOS LOS SIMBOLOS TIENEN LOS MISMOS SIGNIFICADOS QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ACUOSO U ORGANICO A UNA TEMPERATURA ENTRE 0<025>C Y LA DE REFLUJO DE LA MEZCLA DE REACCION. TAMBIEN SE PUEDE HACER REACCIONAR UN COMPUESTO DE FORMULA (IV) CON UN COMPUESTO OMEGA-HALO DE FORMULA (V) EN LAS QUE HAL ES HALOGENO Y LOS DEMAS SIMBOLOS REPRESENTAN LO MISMO QUE EN LA FORMULA (I). ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIHIPERTENSORA E INHIBIDORA DE LA ENZINA DE CONVERSION DE LA ANGIOTENSINA.
ES508706A 1980-12-22 1981-12-22 "procedimiento de preparar acidos aroilaminicos y similares". Granted ES508706A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/219,051 US4440941A (en) 1980-12-22 1980-12-22 Aroyl-aminoacids, amides and esters thereof

Publications (2)

Publication Number Publication Date
ES8300318A1 true ES8300318A1 (es) 1982-11-01
ES508706A0 ES508706A0 (es) 1982-11-01

Family

ID=22817640

Family Applications (1)

Application Number Title Priority Date Filing Date
ES508706A Granted ES508706A0 (es) 1980-12-22 1981-12-22 "procedimiento de preparar acidos aroilaminicos y similares".

Country Status (13)

Country Link
US (1) US4440941A (es)
EP (1) EP0054936B1 (es)
JP (1) JPS57131749A (es)
KR (1) KR830007542A (es)
AT (1) ATE20234T1 (es)
AU (1) AU546887B2 (es)
CA (1) CA1191139A (es)
DE (1) DE3174787D1 (es)
ES (1) ES508706A0 (es)
IE (1) IE52164B1 (es)
IL (1) IL64616A (es)
NZ (1) NZ199358A (es)
ZA (1) ZA818870B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0059536B1 (en) * 1981-03-04 1987-04-22 Imperial Chemical Industries Plc Amide derivatives, processes for preparing them, their use as fungicides and pesticidal compositions containing them
US4717736A (en) * 1984-01-23 1988-01-05 Merck Frosst Canada, Inc. Antagonists of slow reacting substances of anaphylaxis
US5240957A (en) * 1984-01-31 1993-08-31 Astra Lakemedel Akteibolag Oxysalicylamido derivatives
US4560506A (en) * 1984-05-25 1985-12-24 E. R. Squibb & Sons, Inc. Mercaptocycloalkylcarbonyl and mercaptoarylcarbonyl dipeptides
US4647555A (en) * 1984-10-25 1987-03-03 The United States Of America As Represented By The Secretary Of The Army Esters of boron analogues of amino acids
GB8704671D0 (en) * 1987-02-27 1987-04-01 Shell Int Research Glycine compounds
EP0284510A3 (en) * 1987-03-24 1990-08-22 Asahi Breweries, Ltd. N-[N alpha-(1(S)-carboxy-3-cyclohexyl-propyl)-1-lysyl] N-cyclopentylglycine as antihypertensives
EP0384636A1 (en) * 1989-02-21 1990-08-29 FISONS plc Pharmaceutically active compounds
US5801195A (en) * 1994-12-30 1998-09-01 Celgene Corporation Immunotherapeutic aryl amides
EP1886681A3 (en) * 2004-10-07 2008-11-19 Sulfidris S.r.l. 5-(p-hydroxyphenyl)-3H-1,2-dithiol-3-thione valproate ester

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2895992A (en) * 1959-07-21 Process for the production of benzoic
US2603617A (en) * 1946-08-30 1952-07-15 American Cyanamid Co Plasticizing natural and synthetic elastomers by incorporation of n-isopropyl thiosalicylamide
NL281394A (es) * 1961-07-25
JPS5530505B2 (es) * 1973-02-14 1980-08-11
JPS5530506B2 (es) * 1973-04-17 1980-08-11
LU78805A1 (de) * 1977-12-30 1979-07-20 Byk Gulden Lomberg Chem Fab Acylhydrocarbylaminoalkansaeuren,ihre herstellung und verwendung sowie sie enthaltende arzneimittel
JPS54163558A (en) * 1978-06-14 1979-12-26 Biiku Guruden Ronberugu Chem F Substituted amino acid containing medicine* its application and manufacture
DE2923698A1 (de) * 1978-06-14 1980-01-03 Byk Gulden Lomberg Chem Fab Substituierte aminoalkansaeuren, ihre verwendung und herstellung und sie enthaltende arzneimittel
JPS5742662A (en) * 1980-08-29 1982-03-10 Chugai Pharmaceut Co Ltd Benzoic acid amide derivative

Also Published As

Publication number Publication date
IE52164B1 (en) 1987-07-22
IL64616A0 (en) 1982-03-31
AU546887B2 (en) 1985-09-26
IE813039L (en) 1982-06-22
AU7876181A (en) 1982-07-01
CA1191139A (en) 1985-07-30
NZ199358A (en) 1985-04-30
DE3174787D1 (de) 1986-07-10
ES508706A0 (es) 1982-11-01
EP0054936A1 (en) 1982-06-30
US4440941A (en) 1984-04-03
IL64616A (en) 1985-11-29
ZA818870B (en) 1982-11-24
EP0054936B1 (en) 1986-06-04
JPH0231707B2 (es) 1990-07-16
ATE20234T1 (de) 1986-06-15
KR830007542A (ko) 1983-10-21
JPS57131749A (en) 1982-08-14

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