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Laboratorios Frumtost Prem SA
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Laboratorios Frumtost Prem SA
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Application filed by Laboratorios Frumtost Prem SAfiledCriticalLaboratorios Frumtost Prem SA
Priority to ES499110ApriorityCriticalpatent/ES8201992A1/en
Publication of ES499110A0publicationCriticalpatent/ES499110A0/en
Publication of ES8201992A1publicationCriticalpatent/ES8201992A1/en
PROCEDURE FOR THE OBTAINING OF THIAZOLES, OF FORMULA (I) M IN WHICH R1 AND R3 ARE ARILO OR ARILO SUBSTITUTED RADICALS, AND R2 IS AN ALIPHATIC CHAIN WITH A CARBOXYL OR LOW MOLECULAR WEIGHT GROUP. THEY CONSIST OF THE REACTION OF AN A-HALOCETONE OF FORUMALA (II) WITH ARYLAMIDES OF FORMULA R3-CONH2, IN WHICH R1, R2 AND R3 HAVE THE SAME MEANING THAT IN FORMULA (I) AND X MAY BE CHLORINE, JOKE OR IODINE. THE REACTION IS CARRIED OUT IN AN ORGANIC SOLVENT, IN THE PRESENCE OF AN EXCESS OF 50 TO 100 PER 100 PENTASULFIDE OF PHOSPHORUS, AT A TEMPERATURE BETWEEN 80 AND 115C. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS AS ANTI-INFLAMMATORY AGENTS. (Machine-translation by Google Translate, not legally binding)
ES499110A1981-02-041981-02-04Procedure for obtaining tiazoles (Machine-translation by Google Translate, not legally binding)
ExpiredES8201992A1
(en)
Procedure for the preparation of new 2-amino-5-nitrotriazoles replaced in the amino group. (Machine-translation by Google Translate, not legally binding)