ES8201157A1 - Procedimiento para la preparacion de nuevos imidazoles subs-tituidos - Google Patents
Procedimiento para la preparacion de nuevos imidazoles subs-tituidosInfo
- Publication number
- ES8201157A1 ES8201157A1 ES498768A ES498768A ES8201157A1 ES 8201157 A1 ES8201157 A1 ES 8201157A1 ES 498768 A ES498768 A ES 498768A ES 498768 A ES498768 A ES 498768A ES 8201157 A1 ES8201157 A1 ES 8201157A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- general formula
- formula
- represent
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE NUEVOS IMIDAZOLES SUSTITUIDOS, DE FORMULA GENERAL (I), DONDE R1 Y R2 REPRESENTAN UN AOTMO DE HIDROGENO, UN GRUPO ALQUILO INFERIOR CON 4 ATOMOS DE CARBONO, A LO SUMO, O UN GRUPO NITRO, Y DE SUS SALES DE ADICION CON ACIODS ORGANICOS O INORGANICOS FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR, POR CONDENSACION, COMPUESTOS DE FORMULA GENERAL (II), DONDE R1 Y R2 TIENEN LOS SIGNIFICADOS YA INDICADOS, CON COMPUESTOS DE FORMULA GENERAL (III), DONDE X REPRESENTA UN ATOMO DE CLORO, DE BROMO O UN GRUPO DE P-TOSILOXILO, EN UN DISOLVENTE INERTE, Y A TEMPERATURAS COMPRENDIAS ENTRE LA AMBIENTE Y LA REFLUJO DEL DISOLVENTE UTILIZADO.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT19423/80A IT1193371B (it) | 1980-01-24 | 1980-01-24 | 11-(2'-imidazol-1''-il)-acetil-5,11-diidro-6h-pirido 2,3-b 1,4 benzodiazepin-6-oni,metodo per la loro preparazione e la loro applicazione nella terapia dell'ulcera |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8201157A1 true ES8201157A1 (es) | 1981-12-01 |
| ES498768A0 ES498768A0 (es) | 1981-12-01 |
Family
ID=11157749
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES498768A Granted ES498768A0 (es) | 1980-01-24 | 1981-01-23 | Procedimiento para la preparacion de nuevos imidazoles subs-tituidos |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS56113783A (es) |
| BE (1) | BE887069A (es) |
| DE (1) | DE3102152A1 (es) |
| DK (1) | DK32481A (es) |
| ES (1) | ES498768A0 (es) |
| FR (1) | FR2474501A1 (es) |
| GB (1) | GB2068944A (es) |
| GR (1) | GR72993B (es) |
| IT (1) | IT1193371B (es) |
| PT (1) | PT72392B (es) |
| SE (1) | SE8100333L (es) |
| YU (1) | YU16981A (es) |
| ZA (1) | ZA81510B (es) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4210648A (en) * | 1977-05-31 | 1980-07-01 | Boehringer Ingelheim Gmbh | II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof |
-
1979
- 1979-01-22 GR GR63939A patent/GR72993B/el unknown
-
1980
- 1980-01-24 IT IT19423/80A patent/IT1193371B/it active
-
1981
- 1981-01-14 BE BE0/203478A patent/BE887069A/fr unknown
- 1981-01-19 GB GB8101518A patent/GB2068944A/en not_active Withdrawn
- 1981-01-21 SE SE8100333A patent/SE8100333L/xx not_active Application Discontinuation
- 1981-01-22 YU YU00169/81A patent/YU16981A/xx unknown
- 1981-01-23 ES ES498768A patent/ES498768A0/es active Granted
- 1981-01-23 FR FR8101328A patent/FR2474501A1/fr active Pending
- 1981-01-23 DE DE19813102152 patent/DE3102152A1/de not_active Withdrawn
- 1981-01-23 ZA ZA00810510A patent/ZA81510B/xx unknown
- 1981-01-23 DK DK32481A patent/DK32481A/da unknown
- 1981-01-23 JP JP889481A patent/JPS56113783A/ja active Pending
- 1981-01-23 PT PT72392A patent/PT72392B/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SE8100333L (sv) | 1981-07-25 |
| DE3102152A1 (de) | 1981-12-10 |
| DK32481A (da) | 1981-07-25 |
| PT72392B (en) | 1981-12-21 |
| BE887069A (fr) | 1981-05-04 |
| FR2474501A1 (fr) | 1981-07-31 |
| GR72993B (es) | 1984-01-25 |
| ZA81510B (en) | 1982-05-26 |
| JPS56113783A (en) | 1981-09-07 |
| YU16981A (en) | 1983-10-31 |
| IT1193371B (it) | 1988-06-15 |
| ES498768A0 (es) | 1981-12-01 |
| PT72392A (en) | 1981-02-01 |
| GB2068944A (en) | 1981-08-19 |
| IT8019423A0 (it) | 1980-01-24 |
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