ES8200334A1 - Procedure for the obtaining of pharmacologically active alkylthyphenilaminoalcanols (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the obtaining of pharmacologically active alkylthyphenilaminoalcanols (Machine-translation by Google Translate, not legally binding)

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Publication number
ES8200334A1
ES8200334A1 ES496794A ES496794A ES8200334A1 ES 8200334 A1 ES8200334 A1 ES 8200334A1 ES 496794 A ES496794 A ES 496794A ES 496794 A ES496794 A ES 496794A ES 8200334 A1 ES8200334 A1 ES 8200334A1
Authority
ES
Spain
Prior art keywords
translation
procedure
obtaining
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES496794A
Other languages
Spanish (es)
Other versions
ES496794A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fabrica Espanola de Productos Quimicos y Farmaceuticos FAES SA
Original Assignee
Fabrica Espanola de Productos Quimicos y Farmaceuticos FAES SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fabrica Espanola de Productos Quimicos y Farmaceuticos FAES SA filed Critical Fabrica Espanola de Productos Quimicos y Farmaceuticos FAES SA
Priority to ES496794A priority Critical patent/ES8200334A1/en
Publication of ES496794A0 publication Critical patent/ES496794A0/en
Publication of ES8200334A1 publication Critical patent/ES8200334A1/en
Expired legal-status Critical Current

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Abstract

PROCEDURE FOR THE OBTAINING OF FORMULA ALKYLTHIOPHENYLAMANALCANOLS (I), IN WHICH R AND R1 ARE LINEAR OR BRANCHED ALKYL CHAIN RADICALS. IT CONSISTS OF THE REACTION OF THE FOMRULA RX HALIDE, IN WHICH X IS A HALOGEN, WITH A SODIUM OR POTASSIUM THIOPHENATE IN AQUEOUS MEDIUM, FOLLOWED BY THE REACTION WITH CHLORIDE OF THE N-DIACETIL-AMINOPROPIONIC ACID, OF A REACELITION OF A REACTION -CRAFTS, USING ANHYDROUS ALUMINUM TRICHLORIDE AS A CATALYST. THE PRODUCT OBTAINED IS REACTED WITH A FORMULA R1X HALIDE, WHICH FORMS THE SECONDARY AMINE, WHICH IS LATER TRANSFORMED IN THE AMINOALCANOL BY REDUCING THE CARBON GROUP WITH ZINC GRANALLA IN A HALF ACID. THESE COMPOUNDS HAVE PHARMACOLOGICAL APPLICATIONS FOR THEIR VASCULAR AND SPASMOLITIC ACTIVITY. *FORMULA* (Machine-translation by Google Translate, not legally binding)
ES496794A 1980-11-13 1980-11-13 Procedure for the obtaining of pharmacologically active alkylthyphenilaminoalcanols (Machine-translation by Google Translate, not legally binding) Expired ES8200334A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES496794A ES8200334A1 (en) 1980-11-13 1980-11-13 Procedure for the obtaining of pharmacologically active alkylthyphenilaminoalcanols (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES496794A ES8200334A1 (en) 1980-11-13 1980-11-13 Procedure for the obtaining of pharmacologically active alkylthyphenilaminoalcanols (Machine-translation by Google Translate, not legally binding)

Publications (2)

Publication Number Publication Date
ES496794A0 ES496794A0 (en) 1981-11-01
ES8200334A1 true ES8200334A1 (en) 1981-11-01

Family

ID=8481381

Family Applications (1)

Application Number Title Priority Date Filing Date
ES496794A Expired ES8200334A1 (en) 1980-11-13 1980-11-13 Procedure for the obtaining of pharmacologically active alkylthyphenilaminoalcanols (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES8200334A1 (en)

Also Published As

Publication number Publication date
ES496794A0 (en) 1981-11-01

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