ES466867A1 - 2,4 - dichlorophenyl - imidazolyl - ethan - ones and -ols a process for their preparation and their use as medicaments - Google Patents

2,4 - dichlorophenyl - imidazolyl - ethan - ones and -ols a process for their preparation and their use as medicaments

Info

Publication number
ES466867A1
ES466867A1 ES466867A ES466867A ES466867A1 ES 466867 A1 ES466867 A1 ES 466867A1 ES 466867 A ES466867 A ES 466867A ES 466867 A ES466867 A ES 466867A ES 466867 A1 ES466867 A1 ES 466867A1
Authority
ES
Spain
Prior art keywords
ethan
ols
dichlorophenyl
imidazolyl
medicaments
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES466867A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES466867A1 publication Critical patent/ES466867A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Abstract

2,4-Dichlorophenylimidazolyl ethanones or ethanols of the general formula < IMAGE > in which A represents a keto group or a CH(OH) group, X represents halogen, alkyl, or optionally substituted phenyl, and n represents zero or an integer from 1 to 3, and their physiologically tolerated salts, are therapeutically active and are obtained by reacting a compound of the formula II with imidazole. Surprisingly, the active compounds according to the invention demonstrate better antimycotic, therapeutically useful, activity than do the phenoxyimidazolyl derivatives known from the state of the art, which derivatives are the most closely related compounds from the point of view of their chemistry and the nature of their effect.
ES466867A 1977-02-11 1978-02-10 2,4 - dichlorophenyl - imidazolyl - ethan - ones and -ols a process for their preparation and their use as medicaments Expired ES466867A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19772705677 DE2705677A1 (en) 1977-02-11 1977-02-11 2,4-DICHLOROPHENYL-IMIDAZOLYL-AETHANONE (OLE), METHOD FOR MANUFACTURING AND USING THEY AS A MEDICINAL PRODUCT

Publications (1)

Publication Number Publication Date
ES466867A1 true ES466867A1 (en) 1978-10-01

Family

ID=6000864

Family Applications (1)

Application Number Title Priority Date Filing Date
ES466867A Expired ES466867A1 (en) 1977-02-11 1978-02-10 2,4 - dichlorophenyl - imidazolyl - ethan - ones and -ols a process for their preparation and their use as medicaments

Country Status (17)

Country Link
JP (1) JPS53101375A (en)
AT (1) AT361910B (en)
AU (1) AU516580B2 (en)
BE (1) BE863851A (en)
CA (1) CA1097356A (en)
CH (1) CH634058A5 (en)
DE (1) DE2705677A1 (en)
DK (1) DK61378A (en)
ES (1) ES466867A1 (en)
FI (1) FI66851C (en)
FR (1) FR2380263A1 (en)
GB (1) GB1554841A (en)
IL (1) IL54001A (en)
IT (1) IT1093702B (en)
NL (1) NL177214C (en)
NO (1) NO147448C (en)
SE (1) SE442401B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2713777C3 (en) * 1977-03-29 1979-10-31 Bayer Ag, 5090 Leverkusen Process for the preparation of l-azolyl-33-dimethyl-l-phenoxy-butan-2-ones
AT394800B (en) * 1979-09-06 1992-06-25 Bristol Myers Squibb Co Composition for inhibiting the growth of fungi and bacteria
AT382147B (en) * 1979-09-06 1987-01-12 Bristol Myers Co METHOD FOR PRODUCING NEW 1-PHENAETHYLIMIDAZOLE DERIVATIVES
EP0049060A1 (en) * 1980-09-13 1982-04-07 Beecham Group Plc Imidazoles

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2105490C3 (en) * 1971-02-05 1979-06-13 Bayer Ag, 5090 Leverkusen 1-imidazolyl ketone derivatives

Also Published As

Publication number Publication date
GB1554841A (en) 1979-10-31
AU516580B2 (en) 1981-06-11
CA1097356A (en) 1981-03-10
FI780431A (en) 1978-08-12
AT361910B (en) 1981-04-10
IT1093702B (en) 1985-07-26
IL54001A0 (en) 1978-04-30
ATA94378A (en) 1980-09-15
NL177214C (en) 1985-08-16
NO147448B (en) 1983-01-03
CH634058A5 (en) 1983-01-14
FI66851B (en) 1984-08-31
NL177214B (en) 1985-03-18
AU3324378A (en) 1979-08-23
JPS53101375A (en) 1978-09-04
FR2380263A1 (en) 1978-09-08
SE7801526L (en) 1978-08-12
FI66851C (en) 1984-12-10
NO780315L (en) 1978-08-14
IL54001A (en) 1981-09-13
FR2380263B1 (en) 1982-11-19
NL7801579A (en) 1978-08-15
DE2705677A1 (en) 1978-08-17
IT7820129A0 (en) 1978-02-09
SE442401B (en) 1985-12-23
BE863851A (en) 1978-08-10
DK61378A (en) 1978-08-12
NO147448C (en) 1983-04-13

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