ES8200104A1 - Procedure for obtaining 5,11-dihydro-11- (4-methyl-piperacin-1-il) -acethyl) -6h-pirido (2,3-b) (1, k4) benzodiazepin-6-ona and its you go out (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for obtaining 5,11-dihydro-11- (4-methyl-piperacin-1-il) -acethyl) -6h-pirido (2,3-b) (1, k4) benzodiazepin-6-ona and its you go out (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES8200104A1
ES8200104A1 ES497388A ES497388A ES8200104A1 ES 8200104 A1 ES8200104 A1 ES 8200104A1 ES 497388 A ES497388 A ES 497388A ES 497388 A ES497388 A ES 497388A ES 8200104 A1 ES8200104 A1 ES 8200104A1
Authority
ES
Spain
Prior art keywords
piperacin
pirido
benzodiazepin
ona
dihydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497388A
Other languages
Spanish (es)
Other versions
ES497388A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Invest Farmaceutica S A Centro
Original Assignee
Invest Farmaceutica S A Centro
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Invest Farmaceutica S A Centro filed Critical Invest Farmaceutica S A Centro
Priority to ES497388A priority Critical patent/ES497388A0/en
Publication of ES8200104A1 publication Critical patent/ES8200104A1/en
Publication of ES497388A0 publication Critical patent/ES497388A0/en
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Procedure for obtaining 5-11-dihydro-11- (methyl-piperacin-1-il) -acetyl) -6h-pirido (2,3-b) (1,4) benzodiazepin-6-ona, from formula structural (I), and of their pharmaceutically acceptable adhesion salts. Understands the following stages: 1. Through a reaction of aminolysis between the compound 2-chlorine-3-aminopyridine and the isatoic anhydride, carried out with effect with solvents, such as toluene and dioxane at ebullition temperature, the intermediate product is worked 2 -cloro-3- (2 '' - aminobenzoil) -aminopiridine, of structural formula (II); 2. This intermediate product is subjected to an intramolecular cyclation, through a reaction of aminolysis with the deprivation of hydrogen chloride; 3. The compound obtained in the second stage is submitted to acetilation with chloride of chloroactic acid. (Machine-translation by Google Translate, not legally binding)
ES497388A 1980-12-03 1980-12-03 PROCEDURE FOR OBTAINING 5,11-DIHYDRO-11- (4-METHYL-PIPERACIN-1-IL) -ACETIL) -6H-PIRIDO (2,3-B) (1, K4) BENZODIAZEPIN-6-ONA AND ITS YOU GO OUT Granted ES497388A0 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES497388A ES497388A0 (en) 1980-12-03 1980-12-03 PROCEDURE FOR OBTAINING 5,11-DIHYDRO-11- (4-METHYL-PIPERACIN-1-IL) -ACETIL) -6H-PIRIDO (2,3-B) (1, K4) BENZODIAZEPIN-6-ONA AND ITS YOU GO OUT

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES497388A ES497388A0 (en) 1980-12-03 1980-12-03 PROCEDURE FOR OBTAINING 5,11-DIHYDRO-11- (4-METHYL-PIPERACIN-1-IL) -ACETIL) -6H-PIRIDO (2,3-B) (1, K4) BENZODIAZEPIN-6-ONA AND ITS YOU GO OUT

Publications (2)

Publication Number Publication Date
ES8200104A1 true ES8200104A1 (en) 1981-10-16
ES497388A0 ES497388A0 (en) 1981-10-16

Family

ID=8481495

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497388A Granted ES497388A0 (en) 1980-12-03 1980-12-03 PROCEDURE FOR OBTAINING 5,11-DIHYDRO-11- (4-METHYL-PIPERACIN-1-IL) -ACETIL) -6H-PIRIDO (2,3-B) (1, K4) BENZODIAZEPIN-6-ONA AND ITS YOU GO OUT

Country Status (1)

Country Link
ES (1) ES497388A0 (en)

Also Published As

Publication number Publication date
ES497388A0 (en) 1981-10-16

Similar Documents

Publication Publication Date Title
AU4083589A (en) ((1-lower alkyloxy-1-methyl)ethoxy)amines
DE3378763D1 (en) Condensed pyrrolinone derivatives, and their production
FI906438A0 (en) Process for the preparation of new therapeutically useful A-nor-steroid-3-carboxylic acid derivatives
ES8800244A1 (en) and processes for producing the compounds.
NO882588D0 (en) PROCEDURE FOR THE PREPARATION OF SUBSTITUTED INOLOLINO DERIVATIVES.
FR2360643A1 (en) PROCESS FOR PREPARING SULPHURIC HEMI-ESTERS OF HYDROXY-ETHYLSULFONYL GROUPS OF ORGANIC DYES
ES8200104A1 (en) Procedure for obtaining 5,11-dihydro-11- (4-methyl-piperacin-1-il) -acethyl) -6h-pirido (2,3-b) (1, k4) benzodiazepin-6-ona and its you go out (Machine-translation by Google Translate, not legally binding)
ES478706A1 (en) Demethyl maytansinoids and methods for producing them.
AU557494B2 (en) 2-substituted-5-arylimidazoles
FR2446841A1 (en) PROCESS FOR THE PREPARATION OF 1A, 3B-DIHYDROXY-D5-STEROIDES
FI902590A0 (en) FREQUENCY FRAMING FOR 2-OXOINDOL-1-CARBOXAMIDER.
ES8308856A1 (en) 1,3-Disubstituted imidazoles and a process for their production.
FR2423487A1 (en) PROCESS FOR THE PREPARATION OF XANTHONE DERIVATIVES
JPS6419063A (en) Novel heterocyclic compound and use thereof
FR2394525A1 (en) NEW ACID DERIVATIVES (S-PHENENYL TRIS (SULFONYL-IMINO)) - 5.5 ', 5' 'CARBOXYL TRI-BENZENE, USEFUL IN PARTICULAR AS COMPLEMENT INHIBITORS, AND THEIR PROCESS FOR PREPARATION
ES8203332A2 (en) A procedure for preparing an angiotensin converter enzyme inhibitor. (Machine-translation by Google Translate, not legally binding)
JPS572285A (en) Production of benzoheteroring derivative
FR2370035A1 (en) PROCESS FOR THE PREPARATION OF HYDRAZINE AND SUBSTITUTED HYDRAZINES
FR2434142A1 (en) PROCESS FOR THE PREPARATION OF AMINO-HYDROXYANTHRAQUINONES
JPS56150046A (en) Production of 4-dimethylaminostilbene
ES8103087A1 (en) A procedure for preparing biotin (Machine-translation by Google Translate, not legally binding)
ES454265A1 (en) Method for preparing novel cephalosporins
FR2552430B1 (en) PROCESS FOR THE PREPARATION OF QUINOLINONES-4
JPS5759887A (en) Production of dibenzothiepinpropionamide derivative
JPS53112868A (en) Production of thienylacetic acid derivative