ES8200104A1 - Procedure for obtaining 5,11-dihydro-11- (4-methyl-piperacin-1-il) -acethyl) -6h-pirido (2,3-b) (1, k4) benzodiazepin-6-ona and its you go out (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for obtaining 5,11-dihydro-11- (4-methyl-piperacin-1-il) -acethyl) -6h-pirido (2,3-b) (1, k4) benzodiazepin-6-ona and its you go out (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES8200104A1 ES8200104A1 ES497388A ES497388A ES8200104A1 ES 8200104 A1 ES8200104 A1 ES 8200104A1 ES 497388 A ES497388 A ES 497388A ES 497388 A ES497388 A ES 497388A ES 8200104 A1 ES8200104 A1 ES 8200104A1
- Authority
- ES
- Spain
- Prior art keywords
- piperacin
- pirido
- benzodiazepin
- ona
- dihydro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for obtaining 5-11-dihydro-11- (methyl-piperacin-1-il) -acetyl) -6h-pirido (2,3-b) (1,4) benzodiazepin-6-ona, from formula structural (I), and of their pharmaceutically acceptable adhesion salts. Understands the following stages: 1. Through a reaction of aminolysis between the compound 2-chlorine-3-aminopyridine and the isatoic anhydride, carried out with effect with solvents, such as toluene and dioxane at ebullition temperature, the intermediate product is worked 2 -cloro-3- (2 '' - aminobenzoil) -aminopiridine, of structural formula (II); 2. This intermediate product is subjected to an intramolecular cyclation, through a reaction of aminolysis with the deprivation of hydrogen chloride; 3. The compound obtained in the second stage is submitted to acetilation with chloride of chloroactic acid. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES497388A ES497388A0 (en) | 1980-12-03 | 1980-12-03 | PROCEDURE FOR OBTAINING 5,11-DIHYDRO-11- (4-METHYL-PIPERACIN-1-IL) -ACETIL) -6H-PIRIDO (2,3-B) (1, K4) BENZODIAZEPIN-6-ONA AND ITS YOU GO OUT |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES497388A ES497388A0 (en) | 1980-12-03 | 1980-12-03 | PROCEDURE FOR OBTAINING 5,11-DIHYDRO-11- (4-METHYL-PIPERACIN-1-IL) -ACETIL) -6H-PIRIDO (2,3-B) (1, K4) BENZODIAZEPIN-6-ONA AND ITS YOU GO OUT |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8200104A1 true ES8200104A1 (en) | 1981-10-16 |
ES497388A0 ES497388A0 (en) | 1981-10-16 |
Family
ID=8481495
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES497388A Granted ES497388A0 (en) | 1980-12-03 | 1980-12-03 | PROCEDURE FOR OBTAINING 5,11-DIHYDRO-11- (4-METHYL-PIPERACIN-1-IL) -ACETIL) -6H-PIRIDO (2,3-B) (1, K4) BENZODIAZEPIN-6-ONA AND ITS YOU GO OUT |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES497388A0 (en) |
-
1980
- 1980-12-03 ES ES497388A patent/ES497388A0/en active Granted
Also Published As
Publication number | Publication date |
---|---|
ES497388A0 (en) | 1981-10-16 |
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