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USV Pharmaceutical Corp
Original Assignee
USV Pharmaceutical Corp
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Publication date
Application filed by USV Pharmaceutical CorpfiledCriticalUSV Pharmaceutical Corp
Priority to ES497401ApriorityCriticalpatent/ES497401A0/en
Publication of ES8200084A1publicationCriticalpatent/ES8200084A1/en
Publication of ES497401A0publicationCriticalpatent/ES497401A0/en
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
PROCEDURE FOR THE PRODUCTION OF ORGANIC COMPOUNDS, AMINOBENZAMIDES OF FORMULA (I), IN WHICH AR AND AR'' ARE ARYLIC, ALICYCLIC OR HETERO-CYCLE GROUPS; R1, HIROXI, ALKYL, ALCOXY OR OTHERS; R2 AND R3 HYDROGEN, ALKYLENE OR OTHERS; AND R4 AND R5, HALOGEN OR TRIHALOMETILE. IT IS BASED ON THE ACILATION OF A FORMULA (II) HYDRAZINE WITH A FORMULA (III) SULFAMILAROIL HALIDE, IN WHICH X IS HALOGEN; OR WITH AN ACILATING DERIVATIVE OF EQUIVALENT ACID, LIKE A LOWER ALKYL ESTER, AN ANHYDRIDE, OR OTHERS. THE REACTION IS CARRIED OUT AT ROOM TEMPERATURE, IN AN ORGANIC SOLVENT IMMISCIBLE IN WATER, AND IN THE PRESENCE OF A BASE. APPLICATION AS ANTI-HYPERTENSIVE AND DIURETIC AGENTS IN PHARMACEUTICAL PREPARATIONS. (Machine-translation by Google Translate, not legally binding)
ES497401A1980-12-031980-12-03
PROCEDURE FOR PRODUCING AMINOBENZAMI-DICOS ORGANIC COMPOUNDS
GrantedES497401A0
(en)
A procedure for preparing a selected chemical compound of the group consisting of nitroimidazool-ethyl O-thiocarbamate. (Machine-translation by Google Translate, not legally binding)