ES8107021A1 - Un procedimiento para preparar una solucion oftalmica que contiene una sal de 2-acetil-7-(2-hidroxi-3-isopropilamino- propoxi) benzofurano. - Google Patents

Un procedimiento para preparar una solucion oftalmica que contiene una sal de 2-acetil-7-(2-hidroxi-3-isopropilamino- propoxi) benzofurano.

Info

Publication number
ES8107021A1
ES8107021A1 ES494808A ES494808A ES8107021A1 ES 8107021 A1 ES8107021 A1 ES 8107021A1 ES 494808 A ES494808 A ES 494808A ES 494808 A ES494808 A ES 494808A ES 8107021 A1 ES8107021 A1 ES 8107021A1
Authority
ES
Spain
Prior art keywords
intraocular pressure
ophthalmic solution
component
cellulose
eye
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494808A
Other languages
English (en)
Other versions
ES494808A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kakenyaku Kako KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP11482079A external-priority patent/JPS5639013A/ja
Priority claimed from JP9206780A external-priority patent/JPS5716817A/ja
Priority claimed from JP10094780A external-priority patent/JPS5726614A/ja
Application filed by Kakenyaku Kako KK filed Critical Kakenyaku Kako KK
Publication of ES8107021A1 publication Critical patent/ES8107021A1/es
Publication of ES494808A0 publication Critical patent/ES494808A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE UNA SOLUCION OFTALMICA A BASE DE UNA SAL DE 2-ACETIL-7-(2-HIDROXI-3-ISOPROPILAMINOPROPOXI) BENZOFURANO. CONSTA DE LAS SIGUIENTES ETAPAS: 1. DISOLUCION DE UNO DE LOS SIGUIENTES COMPUESTOS: POLI (ALCOHOL VINILICO), METILCELULOSA, CARBOXIMETILCELULOSA, HIDROXIMETILCELULOSA, HIDROXIETILCELULOSA O HIDROXIPROPILMETILCELULOSA, EN UNA SOLUCION ACUOSA DE UN AGENTE TAMPON DE PH 5,0 A 8,0. 2. ADICION A DICHA SOLUCION DE UNA SAL DE 2-ACETIL-7-(2-HIDROXI-3-ISOPROPILOMINOPROPOXI) BENZOFURANO. 3. AJUSTAR A UNA CONCENTRACION DESEADA POR ADICION DE AGUA A LA SOLUCION RESULTANTE. 4. ESTERILIZAR LA SOLUCION RESULTANTE. T
ES494808A 1979-09-06 1980-09-05 Un procedimiento para preparar una solucion oftalmica que contiene una sal de 2-acetil-7-(2-hidroxi-3-isopropilamino- propoxi) benzofurano. Granted ES494808A0 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP11482079A JPS5639013A (en) 1979-09-06 1979-09-06 Ophthalmic solution for regulating intraocular tension
JP9206780A JPS5716817A (en) 1980-07-05 1980-07-05 Eye drop for adjusting intraocular pressure
JP10094780A JPS5726614A (en) 1980-07-22 1980-07-22 Eye drop for adjusting intraocular pressure

Publications (2)

Publication Number Publication Date
ES8107021A1 true ES8107021A1 (es) 1981-08-16
ES494808A0 ES494808A0 (es) 1981-08-16

Family

ID=27306929

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494808A Granted ES494808A0 (es) 1979-09-06 1980-09-05 Un procedimiento para preparar una solucion oftalmica que contiene una sal de 2-acetil-7-(2-hidroxi-3-isopropilamino- propoxi) benzofurano.

Country Status (5)

Country Link
US (1) US4382953A (es)
EP (1) EP0025202B1 (es)
CA (1) CA1141663A (es)
DE (1) DE3064137D1 (es)
ES (1) ES494808A0 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8426922D0 (en) * 1984-10-24 1984-11-28 Sandoz Ltd Galenic formulation
US4819617A (en) * 1986-09-04 1989-04-11 University Of Florida Viscoelastic material for ophthalmic surgery
US5252318A (en) * 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
DK1372611T3 (da) * 2001-03-26 2006-09-18 Novartis Ag Farmaceutisk sammensætning omfattende staurosporin med ringe vandoplöselighed, et overfladeaktivt stof og en vandoplöselig polymer
JP2006504701A (ja) * 2002-09-30 2006-02-09 マーク・エー・バビザイェフ 眼疾患の局所的治療方法、並びに、その治療用組成物及び治療用手段
WO2010102078A1 (en) 2009-03-04 2010-09-10 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US7851504B2 (en) 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
CN100396667C (zh) * 2006-02-20 2008-06-25 中国医学科学院医药生物技术研究所 一组具有上调骨形成蛋白bmp-2表达活性的五元不饱和杂环化合物
US9522153B2 (en) 2009-12-22 2016-12-20 Allergan, Inc. Compositions and methods for lowering intraocular pressure
US20150031712A1 (en) 2013-03-12 2015-01-29 Moshe Rogosnitzky Therapeutic Compositions Containing Dipyridamole and Treatment Packs Including Such Compositions and Methods for Producing Same
WO2016013993A1 (en) 2014-07-25 2016-01-28 Imuneks Farma Llac Sanayi Ve Ticaret A.Ş. Stable preservative free ophthalmic formulations of opioid antagonists
EA201890014A1 (ru) 2015-06-08 2018-07-31 О.Д. Окьюлар Дискавери Лтд. Терапевтические композиции, содержащие дипиридамол, наборы для лечения, содержащие эти композиции, и способы их производства
US10973775B2 (en) 2017-09-22 2021-04-13 University Of Manitoba Antibacterial nanofiber

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056626A (en) * 1971-05-13 1977-11-01 Kakenyaku Kako Co., Ltd. Pharmaceutical composition containing benzofuran derivative
US3824313A (en) * 1973-03-16 1974-07-16 Nelson Res & Dev Topical opthalmic composition and methods of use
US4127674A (en) * 1977-03-21 1978-11-28 Allergan Pharmaceuticals, Inc. Method of treatment for glaucoma
US4189496A (en) * 1978-02-16 1980-02-19 Merck & Co., Inc. 2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid
US4237130A (en) * 1979-06-21 1980-12-02 Merck & Co., Inc. 2,3-Dihydro-6,7-disubstituted-5-(substituted sulfonyl)benzofuran-2-carboxylic acids
US4229467A (en) * 1979-08-16 1980-10-21 Richardson-Merrell Inc. Alkoxy benzofuran carboxylic acids and salts and esters thereof as hypolipidemic agents

Also Published As

Publication number Publication date
CA1141663A (en) 1983-02-22
EP0025202B1 (en) 1983-07-13
DE3064137D1 (en) 1983-08-18
EP0025202A2 (en) 1981-03-18
US4382953A (en) 1983-05-10
ES494808A0 (es) 1981-08-16
EP0025202A3 (en) 1981-06-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201