ES8106486A1 - Un procedimiento para la preparacion de formulaciones de de-rivados de guanidina y 2-imidazolina. - Google Patents

Un procedimiento para la preparacion de formulaciones de de-rivados de guanidina y 2-imidazolina.

Info

Publication number
ES8106486A1
ES8106486A1 ES494433A ES494433A ES8106486A1 ES 8106486 A1 ES8106486 A1 ES 8106486A1 ES 494433 A ES494433 A ES 494433A ES 494433 A ES494433 A ES 494433A ES 8106486 A1 ES8106486 A1 ES 8106486A1
Authority
ES
Spain
Prior art keywords
group
diarrhoea
veterinary composition
aromatic
group containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES494433A
Other languages
English (en)
Other versions
ES494433A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8106486A1 publication Critical patent/ES8106486A1/es
Publication of ES494433A0 publication Critical patent/ES494433A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE GUANIDINA Y 2-IMIDAZOLINA. CONSTA DE LAS SIGUIENTES ETAPAS: 1. SOMETER A REACCION DE SALIDIFICACION A UN COMPUESTO (I). 2. COMBINAR EL PRODUCTO OBTENIDO CON UN VEHICULO TAL COMO UN PRODUCTO ALIMENTICIO O AGUA. EL COMPUESTO DE FORMULA (I) SE SELECCIONA DE NAFAZOLINA, TIMAZOLINA, TENAFTOXALINA, TRAMAZOLINA, FEDRAZINA, TETRAHIDROZOLINA, XILOMETAZOLINA, OXIMETAZOLINA, KB277, H1032, CLONIDINA, BS 100-141, 2-METIHAFAZOLINA; ST 91. LA COMPOSICION OBTENIDA ESTA EN FORMA DE MULTIDOSIS QUE CONTIENE, AL MENOS, 5 G. DEL COMPUESTO (I), O EN FORMA DE DOSIS UNITARIA, QUE PESA AL MENOS UN GRAMO. TRATAMIENTO O PREVENCION DE DIARREA EN GANADERIA. *FORMULA*
ES494433A 1979-08-23 1980-08-22 Un procedimiento para la preparacion de formulaciones de de-rivados de guanidina y 2-imidazolina. Granted ES494433A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7929434 1979-08-23

Publications (2)

Publication Number Publication Date
ES8106486A1 true ES8106486A1 (es) 1981-07-01
ES494433A0 ES494433A0 (es) 1981-07-01

Family

ID=10507398

Family Applications (1)

Application Number Title Priority Date Filing Date
ES494433A Granted ES494433A0 (es) 1979-08-23 1980-08-22 Un procedimiento para la preparacion de formulaciones de de-rivados de guanidina y 2-imidazolina.

Country Status (14)

Country Link
US (2) US4332814A (es)
EP (2) EP0025269B1 (es)
JP (1) JPS5634628A (es)
AU (1) AU533436B2 (es)
CA (1) CA1156147A (es)
DE (1) DE3071229D1 (es)
DK (1) DK363180A (es)
ES (1) ES494433A0 (es)
GR (1) GR69871B (es)
IE (1) IE51143B1 (es)
IL (1) IL60809A0 (es)
NO (1) NO802497L (es)
NZ (1) NZ194591A (es)
ZA (1) ZA804795B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0025269B1 (en) * 1979-08-23 1985-11-13 Beecham Group Plc Anti-diarrhoea veterinary composition
DE3168754D1 (en) * 1980-07-09 1985-03-21 Beecham Group Plc Clonidine derivatives useful in the treatment of diarrhoea
DE3360148D1 (en) * 1982-02-10 1985-06-05 Beecham Group Plc Guanidine derivatives
GB8313588D0 (en) * 1983-05-17 1983-06-22 Beecham Group Plc Compounds
US4714707A (en) * 1984-01-13 1987-12-22 Rorer Pharmaceutical Corporation Aryl substituted heterocycles for treating gastrointestinal motility dysfunction
DE3428342A1 (de) * 1984-08-01 1986-02-13 Boehringer Ingelheim Vetmedica GmbH, 6507 Ingelheim Futtermittelzusatz zur verbesserung des wachstums bei landwirtschaftlichen nutztieren
US5171575A (en) * 1987-01-19 1992-12-15 Nisshin Flour Milling Co., Ltd. Process for preventing diarrhea in animals
CA1321751C (en) * 1989-02-21 1993-08-31 Eugene C. Crichlow Mechanism mediating ruminal stasis in ruminal lactic acidosis
US5352691A (en) * 1993-02-16 1994-10-04 Thomas Peter G Effective treatment modality for adult respiratory distress syndrome using L-histidine
US5576437A (en) * 1993-12-17 1996-11-19 The Procter & Gamble Company 7-(2-imidazolnylamino) quinoline compounds useful as alpha-2 adrenoceptor agonists
US5578607A (en) * 1993-12-17 1996-11-26 The Procter & Gamble Company 6-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists
AU699041B2 (en) * 1993-12-17 1998-11-19 Board Of Regents Of The University Of Nebraska, The 6-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists
DK0735877T3 (da) * 1993-12-17 2000-11-06 Procter & Gamble 6-(2-imidazolinylamino)quinoxalinforbindelser, der er egnede som alfa-2-adrenoceptoragonister.
US5478858A (en) * 1993-12-17 1995-12-26 The Procter & Gamble Company 5-(2-imidazolinylamino) benzimidazole compounds useful as alpha-2 adrenoceptor agonists
US5869458A (en) * 1994-10-14 1999-02-09 Waite; Christopher S. Frozen rehydration formulation and delivery system therefor
EP0827393B1 (en) * 1995-05-23 2002-10-30 SmithKline Beecham plc Pharmaceutical composition prepared by addition of a flavour vehicle to a medicament
US5916900A (en) 1995-06-29 1999-06-29 The Procter & Gamble Company 7-(2-imidazolinylamino)quinoline compounds useful as alpha-2 adrenoceptor agonists
US5741807A (en) * 1996-09-27 1998-04-21 Cytos Pharmaceuticals, L.P. Histidine compositions and methods for treating or preventing infectious and non-infectious diarrheas
CN1284073A (zh) 1997-11-24 2001-02-14 宝洁公司 5－(2－咪唑啉基氨基)－苯并咪唑衍生物,其制备和作为具有改进的代谢稳定性的a－肾上腺素能受体激动剂的应用
US20040071793A1 (en) * 2002-10-05 2004-04-15 Bobrowski Paul J. Oral rehydration methods and compositions
US20050136105A1 (en) * 2003-12-22 2005-06-23 Allen Marni L. Consumer customized dosage forms
US7371405B2 (en) * 2003-12-22 2008-05-13 Mcneil-Ppc, Inc. Consumer customized dosage forms
TW200806282A (en) * 2006-05-05 2008-02-01 Wyeth Corp Solid dosage formulations
KR200466495Y1 (ko) * 2010-12-14 2013-04-23 황연지 좌변기용 어린이 다리 받침장치

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2731471A (en) * 1956-01-17 Nxg hi
US2842478A (en) * 1955-08-25 1958-07-08 Pfizer & Co C Tetrahydrozoline-central nervous system depressant veterinary compositions and method of using same
FR1217629A (fr) * 1956-07-10 1960-05-04 Ciba Geigy Procédé de préparation de la 2-(p-tertio-butyl-o,o'-diméthyl-phényl-méthyl)-imidazoline et de ses sels
US2915431A (en) * 1956-07-17 1959-12-01 Lab Robert & Carriere Sa Des 2-(2'-isopropyl-4'-chloro-5'-methyl)-phenoxymethyl-2-imidazoline and its pharmaceutical uses
NL286080A (es) * 1961-11-30
BE754935A (fr) * 1969-08-13 1971-02-17 Hoechst Ag 2-(thienyl-3'-amino)-1,3-diazacycloalcenes et leur preparation
SE7407022L (es) * 1973-06-06 1974-12-09 Wander Ag Dr A
NZ183492A (en) * 1976-03-27 1980-04-28 Beecham Group Ltd Veterinary rehydration compositions containing monosaccharide amino acid and citric acid or citrate
CA1072962A (en) 1976-08-11 1980-03-04 George H. Douglas Process for preparing amidinoureas
US4122190A (en) * 1976-10-04 1978-10-24 Sandoz Ltd. Treating acromegaly
EP0025269B1 (en) * 1979-08-23 1985-11-13 Beecham Group Plc Anti-diarrhoea veterinary composition
US4312879A (en) * 1980-08-14 1982-01-26 Richardson-Merrell Inc. Clonidine and lofexidine as antidiarrheal agents

Also Published As

Publication number Publication date
GR69871B (es) 1982-07-20
JPS5634628A (en) 1981-04-06
IE801776L (en) 1981-02-23
IL60809A0 (en) 1980-10-26
IE51143B1 (en) 1986-10-15
EP0025269B1 (en) 1985-11-13
US4520014A (en) 1985-05-28
EP0086428B1 (en) 1987-07-29
AU533436B2 (en) 1983-11-24
US4332814A (en) 1982-06-01
NZ194591A (en) 1983-06-17
DE3071229D1 (en) 1985-12-19
EP0086428A1 (en) 1983-08-24
NO802497L (no) 1981-02-24
AU6163180A (en) 1981-04-09
ES494433A0 (es) 1981-07-01
DK363180A (da) 1981-02-24
ZA804795B (en) 1981-07-29
CA1156147A (en) 1983-11-01
EP0025269A1 (en) 1981-03-18

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