ES8103380A1 - A human serum DNA-binding protein - Google Patents

A human serum DNA-binding protein

Info

Publication number
ES8103380A1
ES8103380A1 ES490396A ES490396A ES8103380A1 ES 8103380 A1 ES8103380 A1 ES 8103380A1 ES 490396 A ES490396 A ES 490396A ES 490396 A ES490396 A ES 490396A ES 8103380 A1 ES8103380 A1 ES 8103380A1
Authority
ES
Spain
Prior art keywords
binding protein
human serum
dna
serum
serum dna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490396A
Other languages
Spanish (es)
Other versions
ES490396A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES490396A0 publication Critical patent/ES490396A0/en
Publication of ES8103380A1 publication Critical patent/ES8103380A1/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57411—Specifically defined cancers of cervix
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6875—Nucleoproteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4703—Regulators; Modulating activity
    • G01N2333/4704—Inhibitors; Supressors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/50—Fibroblast growth factors [FGF]

Abstract

Inhibitor protein X in its substantially pure form having the following characterising properties: (i) it is a protein isolatable from human blood serum (ii) it has a molecular weight of about 64,000 daltons and a Pl of 5.9 (iii) it inhibits bleomycin-induced degradation of PM-2 DNA by binding to the DNA and (iv) it is found in lower concentrations in the serum of human beings having cancer than in the serum of cancer-free human beings. h
ES490396A 1979-04-10 1980-04-09 A human serum DNA-binding protein Expired ES8103380A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2873279A 1979-04-10 1979-04-10

Publications (2)

Publication Number Publication Date
ES490396A0 ES490396A0 (en) 1981-02-16
ES8103380A1 true ES8103380A1 (en) 1981-02-16

Family

ID=21845111

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490396A Expired ES8103380A1 (en) 1979-04-10 1980-04-09 A human serum DNA-binding protein

Country Status (24)

Country Link
JP (1) JPS55143441A (en)
KR (1) KR830002502A (en)
AR (1) AR222700A1 (en)
AT (1) AT365343B (en)
AU (1) AU536522B2 (en)
BE (1) BE882669A (en)
CH (1) CH644453A5 (en)
DE (1) DE3013837A1 (en)
DK (1) DK149980A (en)
ES (1) ES8103380A1 (en)
FI (1) FI801078A (en)
FR (1) FR2454099A1 (en)
GB (1) GB2047712B (en)
GR (1) GR67692B (en)
HU (1) HU183122B (en)
IE (1) IE49981B1 (en)
IL (1) IL59772A (en)
IT (1) IT1143135B (en)
LU (1) LU82345A1 (en)
NL (1) NL8002094A (en)
NO (1) NO801018L (en)
PH (1) PH15637A (en)
SE (1) SE8002602L (en)
ZA (1) ZA802141B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3524644A1 (en) * 1985-07-10 1987-01-15 Heyl Chem Pharm UNDULIN AND ITS PEPTIDE FRAGMENTS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE

Also Published As

Publication number Publication date
GB2047712B (en) 1983-02-23
LU82345A1 (en) 1980-12-16
AU5719380A (en) 1980-10-16
IT8048370A0 (en) 1980-04-09
DK149980A (en) 1980-10-11
BE882669A (en) 1980-10-06
HU183122B (en) 1984-04-28
FR2454099A1 (en) 1980-11-07
NO801018L (en) 1980-10-13
ES490396A0 (en) 1981-02-16
ZA802141B (en) 1981-04-29
CH644453A5 (en) 1984-07-31
AT365343B (en) 1982-01-11
IE800693L (en) 1980-10-10
IL59772A (en) 1983-05-15
AR222700A1 (en) 1981-06-15
SE8002602L (en) 1980-12-09
FR2454099B1 (en) 1984-01-27
DE3013837A1 (en) 1980-10-30
NL8002094A (en) 1980-10-14
FI801078A (en) 1980-10-11
IE49981B1 (en) 1986-01-22
IT1143135B (en) 1986-10-22
JPS55143441A (en) 1980-11-08
ATA195780A (en) 1981-05-15
AU536522B2 (en) 1984-05-10
IL59772A0 (en) 1980-06-30
KR830002502A (en) 1983-05-30
GB2047712A (en) 1980-12-03
GR67692B (en) 1981-09-07
PH15637A (en) 1983-03-11

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